| Singles | |
|---|---|
| 2018 Open de Guadeloupe | |
| Champion |  Dušan Lajović |
| Runner-up |  Denis Kudla |
| Final score | 6–4, 6–0 |
Malek Jaziri was the defending champion but chose not to defend his title.
Dušan Lajović won the title after defeating Denis Kudla 6–4, 6–0 in the final.
Stefanos Tsitsipas (second round)
Gastão Elias (second round) Dušan Lajović (champion)
Ruben Bemelmans (semifinals)
Peter Polansky (second round) Denis Kudla (final)
Calvin Hemery (quarterfinals) Bradley Klahn (quarterfinals)| Semifinals | Final | ||||||||||||
 Christian Garín | 2 | 2 | |||||||||||
| 3/WC | Dušan Lajović | 6 | 6 | ||||||||||
| 3/WC | Dušan Lajović | 6 | 6 | ||||||||||
| 6 | Denis Kudla | 4 | 0 | ||||||||||
| 4 | Ruben Bemelmans | 2 | 66 | ||||||||||
| 6 | Denis Kudla | 6 | 78 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1/WC | S Tsitsipas | 6 | 6 | ||||||||||||||||||||||||
| WC | C Denolly | 3 | 3 | 1/WC | S Tsitsipas | 64 | 5 | ||||||||||||||||||||
| C Garín | 4 | 6 | 77 | C Garín | 77 | 7 | |||||||||||||||||||||
 V Galović | 6 | 2 | 63 | C Garín | 7 | 78 | |||||||||||||||||||||
 J-P Smith | 7 | 4 | J-P Smith | 5 | 66 | ||||||||||||||||||||||
| A Santillan | 5 | 3r | J-P Smith | 77 | 6 | ||||||||||||||||||||||
| Q | Laurent Rochette | 0 | 5 | 5 | P Polansky | 63 | 3 | ||||||||||||||||||||
| 5 | P Polansky | 6 | 7 | C Garín | 2 | 2 | |||||||||||||||||||||
| 3/WC | D Lajović | 6 | 6 | 3/WC | D Lajović | 6 | 6 | ||||||||||||||||||||
| B Bonzi | 3 | 3 | 3/WC | D Lajović | 6 | 6 | |||||||||||||||||||||
 D King | 65 | 6 | 6 | D King | 3 | 4 | |||||||||||||||||||||
| Q | Tom Jomby | 77 | 1 | 2 | 3/WC | D Lajović | 77 | 2 | 6 | ||||||||||||||||||
| C Harrison | 6 | 6 | 8 | B Klahn | 65 | 6 | 3 | ||||||||||||||||||||
| WC | G Mina | 4 | 2 | C Harrison | 6 | 64 | 4 | ||||||||||||||||||||
 A Ward | 2 | 0 | 8 | B Klahn | 3 | 77 | 6 | ||||||||||||||||||||
| 8 | B Klahn | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | C Hemery | 6 | 4 | ||||||||||||||||||||||||
 R Olivo | 3 | 1r | 7 | C Hemery | 2 | 7 | 7 | ||||||||||||||||||||
| Q | S Gillé | 4 | 0 | Alt |  K Uchida | 6 | 5 | 5 | |||||||||||||||||||
| Alt | K Uchida | 6 | 6 | 7 | C Hemery | 2 | 4 | ||||||||||||||||||||
| Q | Evan Song | 7 | 77 | 4 | R Bemelmans | 6 | 6 | ||||||||||||||||||||
| B Schnur | 5 | 61 | Q | E Song | 4 | 4 | |||||||||||||||||||||
| Y Mertens | 5 | 1 | 4 | R Bemelmans | 6 | 6 | |||||||||||||||||||||
| 4 | R Bemelmans | 7 | 6 | 4 | R Bemelmans | 2 | 66 | ||||||||||||||||||||
| 6 | D Kudla | 77 | 2 | 6 | 6 | D Kudla | 6 | 78 | |||||||||||||||||||
| M Bourgue | 61 | 6 | 1 | 6 | D Kudla | 6 | 6 | ||||||||||||||||||||
| PR |  S Giraldo | 2 | 6 | 69 | A Pavić | 1 | 1 | ||||||||||||||||||||
| A Pavić | 6 | 3 | 711 | 6 | D Kudla | 6 | 6 | ||||||||||||||||||||
| Alt | L Glasspool | 4 | 1 | F Peliwo | 3 | 4 | |||||||||||||||||||||
| F Peliwo | 6 | 6 | F Peliwo | 6 | 7 | ||||||||||||||||||||||
| D Novikov | 68 | 4 | 2 | G Elias | 4 | 5 | |||||||||||||||||||||
| 2 | G Elias | 710 | 6 | ||||||||||||||||||||||||
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