| Doubles | |
|---|---|
| 2021 Campeonato Internacional de Tênis de Campinas | |
| Champions |  Rafael Matos Felipe Meligeni Alves |
| Runners-up | Gilbert Klier Júnior Matheus Pucinelli de Almeida |
| Score | 6–3, 6–1 |
Sadio Doumbia and Fabien Reboul were the defending champions [1] but chose not to defend their title.
Rafael Matos and Felipe Meligeni Alves won the title after defeating Gilbert Klier Júnior and Matheus Pucinelli de Almeida 6–3, 6–1 in the final.
Rafael Matos / Felipe Meligeni Alves (champions) Orlando Luz / 
Luis David Martínez (first round)
Mark Vervoort / 
Federico Zeballos (quarterfinals)
Pedro Cachin / Facundo Mena (first round)Guillermo Durán and Roberto Quiroz were the defending champions but only Quiroz chose to defend his title, partnering Yannick Hanfmann. Quiroz lost in the first round to Luis David Martínez and Felipe Meligeni Alves.
Guido Andreozzi and Guillermo Durán were the defending champions but only Durán chose to defend his title, partnering Mariano Kestelboim. Durán lost in the first round to Facundo Mena and Camilo Ugo Carabelli.
Ariel Behar and Gonzalo Escobar were the defending champions but only Escobar chose to defend his title, partnering Diego Hidalgo. Escobar lost in the first round to Íñigo Cervantes and Oriol Roca Batalla.
Orlando Luz and Rafael Matos were the defending champions but only Matos chose to defend his title, partnering João Menezes. Matos withdrew from the tournament before his quarterfinal match.
Marcelo Demoliner and Matwé Middelkoop were the defending champions, but Middelkoop decide to participate in the 2021 Open Sud de France instead. Demoliner was pairing up with Santiago González, but they lost in the first round to Guillermo Durán and Andrés Molteni.
Franco Agamenone and Fernando Romboli were the defending champions but chose not to defend their title.
Sadio Doumbia and Fabien Reboul were the defending champions and successfully defended their title, defeating Guido Andreozzi and Guillermo Durán 7–5, 6–3 in the final.
Lloyd Glasspool and Matt Reid were the defending champions but chose not to defend their title.
Evan King and Julian Lenz were the defending champions but only King chose to defend his title, partnering Jan Zieliński. King lost in the first round to Franco Agamenone and Omar Giacalone.
Rafael Matos and João Menezes were the defending champions but chose not to defend their title.
Radu Albot and Enrique López Pérez were the defending champions but chose not to defend their title.
Andre Begemann and Florin Mergea were the defending champions but chose not to defend their title.
This was the first edition of the tournament.
Facundo Bagnis and Andrés Molteni were the defending champions but chose not to defend their title.
Luis David Martínez and Felipe Meligeni Alves were the defending champions but chose to defend their title with different partners. Martínez partnered Fernando Romboli but lost in the semifinals to Nicolás Barrientos and Alejandro Gómez. Meligeni Alves partnered Rafael Matos but withdrew before the final due to a positive test for COVID-19.
Santiago González and Andrés Molteni defeated Andrej Martin and Tristan-Samuel Weissborn in the final, 7–5, 6–3, to win the doubles tennis title at the 2022 Córdoba Open. It was their third career ATP Tour doubles title together. As alternates, Martin and Weissborn were competing in their second event as a team.
Simone Bolelli and Máximo González were the defending champions but Bolelli chose not to participate. González was scheduled to partner Nicolás Jarry, but Jarry withdrew with a right elbow injury before their first round match.
Rafael Matos and Felipe Meligeni Alves were the defending champions but chose not to defend their title.
Rafael Matos and Felipe Meligeni Alves were the defending champions but only Meligeni Alves chose to defend his title, partnering Matheus Pucinelli de Almeida. Meligeni Alves withdrew before his first round match due to injury.
Rafael Matos and Felipe Meligeni Alves were the defending champions but only Meligeni Alves chose to defend his title, partnering Matheus Pucinelli de Almeida. They withdrew before their first round match.
