| Singles | |
|---|---|
| 2023 Cali Open | |
| Champion |  Federico Delbonis |
| Runner-up | Guido Andreozzi |
| Score | 6–4, 6–7(6–8), 6–3 |
Facundo Mena was the defending champion [1] but chose not to defend his title.
Federico Delbonis won the title after defeating Guido Andreozzi 6–4, 6–7(6–8), 6–3 in the final.
Alejandro Tabilo (quarterfinals) Román Andrés Burruchaga (first round)
Alexis Galarneau (second round)
Nicolás Mejía (second round) Santiago Rodríguez Taverna (semifinals) Federico Delbonis (champion)
João Lucas Reis da Silva (first round) Guido Andreozzi (final)| Semifinals | Final | ||||||||||||
| 5 | Santiago Rodríguez Taverna | 63 | 3 | ||||||||||
| 6 | Federico Delbonis | 77 | 6 | ||||||||||
| 6 | Federico Delbonis | 6 | 66 | 6 | |||||||||
| 8 | Guido Andreozzi | 4 | 78 | 3 | |||||||||
| PR | Pedro Sakamoto | 4 | 4 | ||||||||||
| 8 | Guido Andreozzi | 6 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | A Tabilo | 715 | 6 | ||||||||||||||||||||||||
 Christian Langmo | 613 | 4 | 1 | A Tabilo | 6 | 6 | |||||||||||||||||||||
| Q | JI Londero | 6 | 6 | Q | JI Londero | 3 | 4 | ||||||||||||||||||||
| Q | Ignacio Monzón | 1 | 2 | 1 | A Tabilo | 6 | 3 | 65 | |||||||||||||||||||
| WC | Adrià Soriano Barrera | 3 | 65 | 5 | S Rodríguez Taverna | 4 | 6 | 77 | |||||||||||||||||||
 N Serdarušić | 6 | 77 | N Serdarušić | 65 | 4 | ||||||||||||||||||||||
 M Sasikumar | 63 | 65 | 5 | S Rodríguez Taverna | 77 | 6 | |||||||||||||||||||||
| 5 | S Rodríguez Taverna | 77 | 77 | 5 | S Rodríguez Taverna | 63 | 3 | ||||||||||||||||||||
| 4/WC | N Mejía | 6 | 6 | 6 | F Delbonis | 77 | 6 | ||||||||||||||||||||
| Q | Alejandro Hoyos | 2 | 1 | 4/WC | N Mejía | 2 | 2 | ||||||||||||||||||||
| Alt | G Heide | 6 | 6 | Alt | G Heide | 6 | 6 | ||||||||||||||||||||
 MH Rehberg | 3 | 3 | Alt | G Heide | 0 | 2 | |||||||||||||||||||||
 T Schoolkate | 77 | 7 | 6 | F Delbonis | 6 | 6 | |||||||||||||||||||||
| PR | T-S Kwiatkowski | 65 | 5 | T Schoolkate | 67 | 1 | |||||||||||||||||||||
| E Ribeiro | 2 | 3 | 6 | F Delbonis | 79 | 6 | |||||||||||||||||||||
| 6 | F Delbonis | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | JL Reis da Silva | 3 | 6 | 3 | |||||||||||||||||||||||
 G Melzer | 6 | 3 | 6 | G Melzer | 6 | 77 | |||||||||||||||||||||
| A Rybakov | 4 | 63 | Alt | O Luz | 4 | 65 | |||||||||||||||||||||
| Alt | O Luz | 6 | 77 | G Melzer | 77 | 4 | 68 | ||||||||||||||||||||
| PR | P Sakamoto | 7 | 6 | PR | P Sakamoto | 64 | 6 | 710 | |||||||||||||||||||
| P Kypson | 5 | 3 | PR | P Sakamoto | 77 | 6 | |||||||||||||||||||||
| Q | G Lama | 3 | 6 | 3 | 3 | A Galarneau | 65 | 2 | |||||||||||||||||||
| 3 | A Galarneau | 6 | 3 | 6 | PR | P Sakamoto | 4 | 4 | |||||||||||||||||||
| 8 | G Andreozzi | 6 | 6 | 8 | G Andreozzi | 6 | 6 | ||||||||||||||||||||
 B Lock | 4 | 4 | 8 | G Andreozzi | 77 | 6 | |||||||||||||||||||||
| MF Descotte | 6 | 7 | MF Descotte | 62 | 3 | ||||||||||||||||||||||
| WC | Johan Alexander Rodríguez | 3 | 5 | 8 | G Andreozzi | 6 | 6 | ||||||||||||||||||||
| PR |  R Statham | 1r | Q | P Boscardin Dias | 3 | 2 | |||||||||||||||||||||
| Q | P Boscardin Dias | 4 | Q | P Boscardin Dias | 6 | 6 | |||||||||||||||||||||
| Q | M Soto | 6 | 6 | Q | M Soto | 4 | 3 | ||||||||||||||||||||
| 2 | RA Burruchaga | 2 | 4 | ||||||||||||||||||||||||
Thiago Alves is the defending champion but lost in the quarterfinals to Gastão Elias.
Horacio Zeballos defeated Rogério Dutra da Silva 7–6(7–5), 6–2 in the final to win the title.
Horacio Zeballos defeated Rafael Nadal in the final, 6–7(2–7), 7–6(8–6), 6–4 to win the singles tennis title at the 2013 Chile Open. It was Nadal's first tournament in eight months.
Pablo Cuevas was the two-time defending champion and successfully defended his title, defeating Albert Ramos Viñolas in the final, 6–7(3–7), 6–4, 6–4.
Marco Cecchinato was the defending champion but lost in the semifinals to Federico Delbonis.
Renzo Olivo was the defending champion but lost in the quarterfinals to Horacio Zeballos.
Stefanos Tsitsipas was the defending champion but chose not to defend his title.
Richard Gasquet was the defending champion but chose not to defend his title.
Víctor Estrella Burgos was the defending champion but lost in the first round to Federico Delbonis.
Gerald Melzer was the defending champion but lost in the first round to Paolo Lorenzi.
Gerald Melzer was the defending champion but lost in the first round to Federico Coria.
Fabio Fognini defeated Dušan Lajović in the final, 6–3, 6–4 to win the singles tennis title at the 2019 Monte-Carlo Masters. It was his first ATP Tour Masters 1000 title.
Dominic Thiem defeated Daniil Medvedev in the final, 6–4, 6–0, to win the singles title at the 2019 Barcelona Open.
Pablo Andújar was the defending champion but chose not to defend his title.
Guido Andreozzi and Guillermo Durán were the defending champions but only Andreozzi chose to defend his title, partnering Andrés Molteni. Andreozzi successfully defended his title.
Cristian Garín was the defending champion but chose not to defend his title.
Cristian Garín was the defending champion but chose not to defend his title.
Dominic Thiem was the defending champion and chose not to defend his title, as he was still competing at the 2020 US Open.
Cristian Garín was the defending champion, but chose not to defend his title.
Rafael Matos and Felipe Meligeni Alves were the defending champions but only Meligeni Alves chose to defend his title, partnering Matheus Pucinelli de Almeida. Meligeni Alves withdrew before his first round match due to injury.
This was the first edition of the tournament.