AF4/FMR2 family member 3 is a protein that in humans is encoded by the AFF3 gene. [5] [6] [7]
AF4/FMR2 family member 3 is a protein that in humans is encoded by the AFF3 gene. [5] [6] [7]
This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [7]
Histone-lysine N-methyltransferase 2A also known as acute lymphoblastic leukemia 1 (ALL-1), myeloid/lymphoid or mixed-lineage leukemia1 (MLL1), or zinc finger protein HRX (HRX) is an enzyme that in humans is encoded by the KMT2A gene.
SCL-interrupting locus protein is a protein that in humans is encoded by the STIL gene.
Factor interacting with PAPOLA and CPSF1 is a protein that in humans is encoded by the FIP1L1 gene. A medically important aspect of the FIP1L1 gene is its fusion with other genes to form fusion genes which cause clonal hypereosinophilia and leukemic diseases in humans.
AF4/FMR2 family member 1 is a protein that in humans is encoded by the AFF1 gene. At its same location was a record for a separate PBM1 gene, which has since been withdrawn and considered an alias. It was previously known as AF4.
Hepatic leukemia factor is a protein that in humans is encoded by the HLF gene.
T-cell leukemia homeobox protein 1 is a protein that in humans is encoded by the TLX1 gene, which was initially named HOX11.
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.
Lysine N-methyltransferase 2C (KMT2C) also known as myeloid/lymphoid or mixed-lineage leukemia protein 3 (MLL3) is an enzyme that in humans is encoded by the KMT2C gene.
AF4/FMR2 family member 2 is a protein that in humans is encoded by the AFF2 gene. Mutations in AFF2 are implicated in cases of breast cancer.
T-cell leukemia homeobox protein 3 is a protein that in humans is encoded by the TLX3 gene.
Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.
Phosphatidylinositol binding clathrin assembly protein, also known as PICALM, is a protein which in humans is encoded by the PICALM gene.
Protein AF-9 is a protein that in humans is encoded by the MLLT3 gene.
NCK-interacting protein with SH3 domain is a protein that in humans is encoded by the NCKIPSD gene.
Protein ENL is a protein that in humans is encoded by the MLLT1 gene.
Myeloid/lymphoid or mixed-lineage leukemia 4, also known as MLL4, is a human gene.
AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene.
T-cell acute lymphocytic leukemia 2, also known as TAL2, is a protein which in humans is encoded by the TAL2 gene.
Lysine methyltransferase 2E is a protein that in humans is encoded by the KMT2E gene.
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