AGBL4

AGBL4
Identifiers
Aliases	AGBL4 , CCP6, ATP/GTP binding protein-like 4, ATP/GTP binding protein like 4, AGBL carboxypeptidase 4
External IDs	OMIM: 616476 MGI: 1918244 HomoloGene: 84880 GeneCards: AGBL4
Gene location (Human)
Chr.	Chromosome 1 (human)
End	50,023,954 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	111,521,521 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; Brodmann area 23; ; Brodmann area 9; ; middle temporal gyrus; ; right uterine tube; ; islet of Langerhans; ; pituitary gland; ; hypothalamus; ; anterior pituitary; ; nucleus accumbens;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; Jacobson's organ; ; superior frontal gyrus; ; substantia nigra; ; supraoptic nucleus; ; sensory ganglion; ; hippocampus proper; ; cerebellar cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	carboxypeptidase activity ; tubulin binding ; zinc ion binding ; peptidase activity ; hydrolase activity ; metallopeptidase activity ; metal ion binding ; metallocarboxypeptidase activity ;
Cellular component	cytoplasm ; ciliary basal body ; centriole ; cytosol ; Golgi apparatus ; cell projection ; cytoskeleton ;
Biological process	C-terminal protein deglutamylation ; protein side chain deglutamylation ; proteolysis ; protein deglutamylation ; defense response to virus ;
	Sources:Amigo / QuickGO
Orthologs
	84871
	78933
	ENSG00000186094
	ENSMUSG00000061298
	Q5VU57
	Q09LZ8
	NM_032785 ; NM_001323573 ; NM_001323574 ; NM_001323575
	NM_001048189 ; NM_001284190 ; NM_030231
	NP_001310502 ; NP_001310503 ; NP_001310504 ; NP_116174
	NP_001041654 ; NP_001271119 ; NP_084507
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 25, 2024

ATP/GTP binding protein like 4 is a protein that in humans is encoded by the AGBL4 gene. ^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000186094 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000061298 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: ATP/GTP binding protein like 4".

Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C (August 2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling". Gut. 58 (8): 1078–83. doi:10.1136/gut.2008.169052. PMID 19240061. S2CID 17111427.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Molecular Medicine. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464 . PMID 20379614.
Wu HY, Rong Y, Correia K, Min J, Morgan JI (January 2015). "Comparison of the enzymatic and functional properties of three cytosolic carboxypeptidase family members". The Journal of Biological Chemistry. 290 (2): 1222–32. doi: 10.1074/jbc.M114.604850 . PMC 4294487 . PMID 25416787.
Lin PC, Lin JK, Lin CH, Lin HH, Yang SH, Jiang JK, Chen WS, Chou CC, Tsai SF, Chang SC (December 2015). "Clinical Relevance of Plasma DNA Methylation in Colorectal Cancer Patients Identified by Using a Genome-Wide High-Resolution Array". Annals of Surgical Oncology. 22 (Suppl 3): S1419-27. doi:10.1245/s10434-014-4277-2. PMID 25472652. S2CID 13377596.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000186094 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000061298 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: ATP/GTP binding protein like 4".

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AGBL4

Related Research Articles

References

Further reading