AGPAT5

AGPAT5
Identifiers
Aliases	AGPAT5 , 1LPAATE, 1-acylglycerol-3-phosphate O-acyltransferase 5
External IDs	OMIM: 614796 MGI: 1196345 HomoloGene: 10153 GeneCards: AGPAT5
Gene location (Human)
Chr.	Chromosome 8 (human)
End	6,761,503 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	18,941,377 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; ganglionic eminence; ; endometrium; ; Achilles tendon; ; caudate nucleus; ; islet of Langerhans; ; nucleus accumbens; ; putamen; ; temporal lobe; ; amygdala;
	Top expressed in
	triceps brachii muscle; ; sternocleidomastoid muscle; ; temporal muscle; ; digastric muscle; ; seminal vesicula; ; pineal gland; ; belly cord; ; lacrimal gland; ; skin of back; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity ; protein binding ; acyltransferase activity ; 1-acylglycerol-3-phosphate O-acyltransferase activity ;
Cellular component	integral component of membrane ; nuclear envelope ; membrane ; endoplasmic reticulum membrane ; mitochondrial outer membrane ; mitochondrion ; endoplasmic reticulum ; nucleus ;
Biological process	phosphatidic acid biosynthetic process ; CDP-diacylglycerol biosynthetic process ; lipid metabolism ; hematopoietic progenitor cell differentiation ; phospholipid biosynthetic process ; metabolism ; acylglycerol metabolic process ; phospholipid metabolic process ;
	Sources:Amigo / QuickGO
Orthologs
	55326
	52123
	ENSG00000155189 ; ENSG00000284980
	ENSMUSG00000031467
	Q9NUQ2
	Q9D1E8
	NM_018361
	NM_026792
	NP_060831
	NP_081068
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 27, 2024

1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon is an enzyme that is encoded by the AGPAT5 gene in humans.^[5]

Related Research Articles

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References

1 2 3 ENSG00000284980 GRCh38: Ensembl release 89: ENSG00000155189, ENSG00000284980 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031467 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 "Entrez Gene: AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)".

External links

Human AGPAT5 genome location and AGPAT5 gene details page in the UCSC Genome Browser .

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Lu B, Jiang YJ, Zhou Y, et al. (2005). "Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart". Biochem. J. 385 (Pt 2): 469–77. doi:10.1042/BJ20041348. PMC 1134718 . PMID 15367102.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Agarwal AK, Barnes RI, Garg A (2006). "Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity". Arch. Biochem. Biophys. 449 (1–2): 64–76. doi:10.1016/j.abb.2006.03.014. PMID 16620771.

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[refGRCh38Ensembl-1] 1 2 3 ENSG00000284980 GRCh38: Ensembl release 89: ENSG00000155189, ENSG00000284980 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031467 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 "Entrez Gene: AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)".

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AGPAT5

Contents

Related Research Articles

References

External links

Further reading