AHCTF1

AHCTF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4I0O
Identifiers
Aliases	AHCTF1 , ELYS, MST108, TMBS62, MSTP108, AT-hook containing transcription factor 1
External IDs	OMIM: 610853; MGI: 1915033; HomoloGene: 9142; GeneCards: AHCTF1; OMA:AHCTF1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 246,839,098 bp [1] End 246,931,948 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1 H4|1 83.62 cM Start 179,572,459 bp [2] End 179,631,245 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell Achilles tendon secondary oocyte sperm ventricular zone Brodmann area 23 testicle internal globus pallidus left testis middle temporal gyrus Top expressed in tail of embryo spermatocyte spermatid genital tubercle epiblast seminiferous tubule zygote secondary oocyte otic placode otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm cytosol nuclear membrane nuclear periphery nuclear matrix nuclear pore nucleoplasm chromosome nuclear pore outer ring chromatin extracellular exosome chromosome, centromeric region nucleus kinetochore nuclear envelope Biological process mRNA transport nuclear pore complex assembly regulation of transcription, DNA-templated cytokinesis cell division protein transport cell cycle sister chromatid cohesion transport regulation of transcription by RNA polymerase II regulation of cytokinesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25909 226747 Ensembl ENSG00000153207 ENSMUSG00000026491 UniProt Q8WYP5 Q8CJF7 RefSeq (mRNA) NM_015446 NM_001323342 NM_001323343 NM_175865 NM_026375 RefSeq (protein) NP_001310271 NP_001310272 NP_056261 NP_080651 Location (UCSC) Chr 1: 246.84 – 246.93 Mb Chr 1: 179.57 – 179.63 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene. ^{[5] [6]}

See also

• AT-hook

References

1. GRCh38: Ensembl release 89: ENSG00000153207 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026491 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Natori O, Nobuhisa I, Taga T (Apr 2002). "Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues". Genes Cells. 7 (4): 435–46. doi:10.1046/j.1365-2443.2002.00529.x. PMID   11952839. S2CID   22977237.
6. "Entrez Gene: AHCTF1 AT hook containing transcription factor 1".

External links

• Human AHCTF1 genome location and AHCTF1 gene details page in the UCSC Genome Browser .

Further reading

• Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17801–6. doi: 10.1073/pnas.0608484103 . PMC   1635652 . PMID   17098863.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID   16964243. S2CID   14294292.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC   1459365 . PMID   16565220.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.