AKIP1

AKIP1
Identifiers
Aliases	AKIP1 , BCA3, C11orf17, A-kinase interacting protein 1
External IDs	OMIM: 609191; MGI: 3041226; HomoloGene: 10765; GeneCards: AKIP1; OMA:AKIP1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	8,920,084 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	109,311,396 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; right adrenal cortex; ; left adrenal cortex; ; stromal cell of endometrium; ; Descending thoracic aorta; ; germinal epithelium; ; ascending aorta; ; right coronary artery; ; muscle of thigh;
	Top expressed in
	right kidney; ; left lobe of liver; ; proximal tubule; ; seminiferous tubule; ; fetal liver hematopoietic progenitor cell; ; sciatic nerve; ; olfactory epithelium; ; lacrimal gland; ; transitional epithelium of urinary bladder; ; Paneth cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ;
Cellular component	nucleoplasm ; nucleus ;
Biological process	substrate adhesion-dependent cell spreading ; regulation of NIK/NF-kappaB signaling ;
	Sources:Amigo / QuickGO
Orthologs
	56672
	57373
	ENSG00000166452
	ENSMUSG00000031023
	Q9NQ31
	Q9JJR5
NM_001206645 ; NM_001206646 ; NM_001206647 ; NM_001206648 ; NM_020642 ;
	NM_182901
	NM_020616
	NP_001193575 ; NP_001193576 ; NP_001193577 ; NP_065693
	NP_065641
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated July 17, 2025

A kinase (PRKA) interacting protein 1 is a protein in humans that is encoded by the AKIP1 gene.^[5]

This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011].

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000166452 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031023 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: A kinase (PRKA) interacting protein 1".

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000166452 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031023 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: A kinase (PRKA) interacting protein 1".

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