ANP32B

ANP32B
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2ELL, 2RR6
Identifiers
Aliases	ANP32B , APRIL, PHAPI2, SSP29, acidic nuclear phosphoprotein 32 family member B
External IDs	HomoloGene: 21286 GeneCards: ANP32B
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q22.33 Start 97,983,341 bp [1] End 98,015,943 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cancellous bone optic nerve thymus internal globus pallidus corpus epididymis parotid gland caput epididymis inferior olivary nucleus inferior ganglion of vagus nerve hair follicle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function histone binding protein binding RNA polymerase binding Cellular component cytoplasm extracellular exosome nucleolus nucleus Biological process positive regulation of protein export from nucleus negative regulation of cell differentiation inner ear development nucleosome assembly roof of mouth development vasculature development activation of cysteine-type endopeptidase activity involved in apoptotic process ventricular system development histone exchange Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10541 n/a Ensembl ENSG00000136938 n/a UniProt Q92688 n/a RefSeq (mRNA) NM_006401 n/a RefSeq (protein) NP_006392 n/a Location (UCSC) Chr 9: 97.98 – 98.02 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) also known as "acidic protein rich in leucines" (APRIL) is a protein that in humans is encoded by the ANP32B gene. ^{[3] [4] [5]}

APRIL is also the acronym used for an entirely different protein, TNFSF13, a member of the tumor necrosis factor superfamily whose alternative name, A PRoliferation Inducing Ligand, shares the same acronym as that for ANP32B

See also

• ANP32A, ANP32C, ANP32D, ANP32E

References

1. GRCh38: Ensembl release 89: ENSG00000136938 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Zhu L, Perlaky L, Henning D, Valdez BC (Jan 1998). "Cloning and characterization of a new silver-stainable protein SSP29, a member of the LRR family". Biochem Mol Biol Int. 42 (5): 927–35. doi: 10.1080/15216549700203371 . PMID   9285060. S2CID   19749385.
4. Mencinger M, Panagopoulos I, Contreras JA, Mitelman F, Aman P (Mar 1998). "Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines". Biochim Biophys Acta. 1395 (2): 176–80. doi:10.1016/S0167-4781(97)00165-6. PMID   9473664.
5. "Entrez Gene: ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B".

External links

• Human ANP32B genome location and ANP32B gene details page in the UCSC Genome Browser .

Further reading

• Matilla A, Radrizzani M (2005). "The Anp32 family of proteins containing leucine-rich repeats". Cerebellum. 4 (1): 7–18. doi:10.1080/14734220410019020. PMID   15895553. S2CID   39153579.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Brennan CM, Gallouzi IE, Steitz JA (2000). "Protein ligands to HuR modulate its interaction with target mRNAs in vivo". J. Cell Biol. 151 (1): 1–14. doi:10.1083/jcb.151.1.1. PMC   2189805 . PMID   11018049.
• Gallouzi IE, Steitz JA (2001). "Delineation of mRNA export pathways by the use of cell-permeable peptides". Science. 294 (5548): 1895–901. doi:10.1126/science.1064693. PMID   11729309. S2CID   43726887.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Jiang X, Kim HE, Shu H, et al. (2003). "Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway". Science. 299 (5604): 223–6. doi:10.1126/science.1076807. PMID   12522243. S2CID   86628810.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Tao WA, Wollscheid B, O'Brien R, et al. (2005). "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry". Nat. Methods. 2 (8): 591–8. doi:10.1038/nmeth776. PMID   16094384. S2CID   20475874.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.