AP1G2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | AP1G2 , G2AD, adaptor related protein complex 1 gamma 2 subunit, adaptor related protein complex 1 subunit gamma 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 603534 MGI: 1328307 HomoloGene: 49141 GeneCards: AP1G2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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AP-1 complex subunit gamma-like 2 is a protein that in humans is encoded by the AP1G2 gene. [5] [6] [7]
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. There are two alternatively spliced transcript variants of this gene encoding the same protein. [7]
ADP-ribosylation factor-binding protein GGA1 is a protein that in humans is encoded by the GGA1 gene.
AP-2 complex subunit mu is a protein that in humans is encoded by the AP2M1 gene.
Coatomer subunit beta is a protein that in humans is encoded by the COPB1 gene.
AP-2 complex subunit alpha-1 is a protein that in humans is encoded by the AP2A1 gene.
AP-1 complex subunit mu-1 is a protein that in humans is encoded by the AP1M1 gene.
AP-1 complex subunit gamma-1 is a protein that in humans is encoded by the AP1G1 gene.
DNA damage-binding protein 1 is a protein that in humans is encoded by the DDB1 gene.
5'-AMP-activated protein kinase subunit gamma-2 is an enzyme that in humans is encoded by the PRKAG2 gene.
AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.
AP-1 complex subunit beta-1 is a protein that in humans is encoded by the AP1B1 gene.
AP-2 complex subunit beta is a protein that in humans is encoded by the AP2B1 gene.
Transcription initiation factor TFIID subunit 2 is a protein that in humans is encoded by the TAF2 gene.
AP-3 complex subunit delta-1 is a protein that in humans is encoded by the AP3D1 gene.
AP-1 complex subunit sigma-1A is a protein that in humans is encoded by the AP1S1 gene.
AP-3 complex subunit mu-1 is a protein that in humans is encoded by the AP3M1 gene.
AP-1 complex subunit sigma-2 is a protein that in humans is encoded by the AP1S2 gene.
Synergin gamma also known as AP1 subunit gamma-binding protein 1 (AP1GBP1) is a protein that in humans is encoded by the SYNRG gene.
AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene.
Vacuolar-sorting protein SNF8 is a protein that in humans is encoded by the SNF8 gene.
AP-4 complex subunit mu-1 is a protein that in humans is encoded by the AP4M1 gene.