Allergen of the Year is an annual "award" voted upon by the American Contact Dermatitis Society, aiming to raise awareness about common allergens. The purpose of the award is "to draw attention to the agents causing the most significant clinical effects, those that are underrecognized and those that have become obsolete or for which exposure patterns have changed". [1]
Year | Allergen | Description | References |
---|---|---|---|
2024 | Sulfites | Group of compounds used to preserve food and drink products. | [2] |
2023 | Lanolin | Natural wax from sheep's wool, often used in skincare products. | [3] |
2022 | Aluminium | Common metal. | [4] |
2021 | Acetophenone azine | Compound found in EVA foam, used in sporting equipment and footwear. | [5] [6] |
2020 | Isobornyl acrylate | Used in medical devices for diabetes patients. | [7] [8] |
2019 | Parabens (selected as a non-allergen) | "One of the least allergenic preservatives available". | [9] [10] |
2018 | Propylene glycol | Used in foods and cosmetics | [11] |
2017 | Alkyl glucoside | – | [12] |
2016 | Cobalt | Metal | [13] |
2015 | Formaldehyde | Preservative | [14] |
2014 | Benzophenones | – | [15] [16] |
2013 | Methylisothiazolinone | This chemical is used as a preservative in many cosmetics, lotions, and makeup removers; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area. | [17] |
2012 | Acrylate | – | [18] [19] |
2011 | Dimethyl fumarate | Chemical often used to inhibit the growth of mold. Has been banned in consumer products in the European Union since 2009. | [20] [21] [22] |
2010 | Neomycin | Common antibiotic. | [23] [24] |
2009 | Mixed dialkyl thiourea | Neoprene rubber is a common source. | [25] [26] |
2008 | Nickel | Cheap metal, widely used in coins and household items. | [27] [28] |
2007 | Fragrance | A variety of compounds with smells or odours. | [29] |
2006 | p-Phenylenediamine | Common hair dye chemical that is used to augment black henna tattoos. It has been shown to cause severe blistering and scarring, and its topical use is banned in some countries. | [30] [31] |
2005 | Corticosteroids | A class of steroid hormones, can be used to treat a variety of medical conditions. | [32] [33] |
2004 | Cocamidopropyl betaine | A mixture of closely related organic compounds, used in soaps and shampoos. | [34] [35] |
2003 | Bacitracin | Common antibiotic. | [36] [37] |
2002 | Thimerosal | Well-established antiseptic and antifungal agent, often used in medicines and vaccines. | [38] [39] |
2001 | Gold | Precious metal, used often in jewelry. | [40] [41] |
2000 | Disperse blue dye | Dye used to color synthetic textiles. | [42] [43] |
Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid. It is almost odorless and has a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH. As it contains two alcohol groups, it is classified as a diol. An aliphatic diol may also be called a glycol. It is miscible with a broad range of solvents, including water, acetone, and chloroform. In general, glycols are non-irritating and have very low volatility.
Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against Gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen. It is generally not effective against Gram-positive bacilli and anaerobic Gram-negative bacilli. Neomycin comes in oral and topical formulations, including creams, ointments, and eyedrops. Neomycin belongs to the aminoglycoside class of antibiotics that contain two or more amino sugars connected by glycosidic bonds.
p-Phenylenediamine (PPD) is an organic compound with the formula C6H4(NH2)2. This derivative of aniline is a white solid, but samples can darken due to air oxidation. It is mainly used as a component of engineering polymers and composites like kevlar. It is also an ingredient in hair dyes and is occasionally used as a substitute for henna.
Contact dermatitis is a type of acute or chronic inflammation of the skin caused by exposure to chemical or physical agents. Symptoms of contact dermatitis can include itchy or dry skin, a red rash, bumps, blisters, or swelling. These rashes are not contagious or life-threatening, but can be very uncomfortable.
An aroma compound, also known as an odorant, aroma, fragrance or flavoring, is a chemical compound that has a smell or odor. For an individual chemical or class of chemical compounds to impart a smell or fragrance, it must be sufficiently volatile for transmission via the air to the olfactory system in the upper part of the nose. As examples, various fragrant fruits have diverse aroma compounds, particularly strawberries which are commercially cultivated to have appealing aromas, and contain several hundred aroma compounds.
Quaternium-15 is a quaternary ammonium salt that has been used as a surfactant and preservative. It acts as an antimicrobial agent because it slowly releases formaldehyde, which is a preservative with biocidal properties.
Dyshidrosis is a type of dermatitis, characterized by itchy vesicles of 1–2 mm in size, on the palms of the hands, sides of fingers, or bottoms of the feet. Outbreaks usually conclude within three to four weeks, but often recur. Repeated attacks may result in fissures and skin thickening. The cause of the condition is not known.
Bronopol is an organic compound that is used as an antimicrobial. It is a white solid although commercial samples appear yellow.
A patch test is a diagnostic method used to determine which specific substances cause allergic inflammation of a patient's skin.
Cocamidopropyl betaine (CAPB) is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine. CAPB is available as a viscous pale yellow solution and it is used as a surfactant in personal care products and animal husbandry. The name reflects that the major part of the molecule, the lauric acid group, is derived from coconut oil. Cocamidopropyl betaine to a significant degree has replaced cocamide DEA.
Allergic contact dermatitis (ACD) is a form of contact dermatitis that is the manifestation of an allergic response caused by contact with a substance; the other type being irritant contact dermatitis (ICD).
Hydroxymethylpentylcyclohexenecarboxaldehyde is a synthetic fragrance known by the trade names Lyral, Kovanol, Mugonal, Landolal. It is found in some soaps, eau de toilettes, aftershaves and deodorants.
Diazolidinyl urea is an antimicrobial preservative used in cosmetics. It is chemically related to imidazolidinyl urea which is used in the same way. Diazolidinyl urea acts as a formaldehyde releaser.
Thiuram disulfides are a class of organosulfur compounds with the formula (R2NCSS)2. Many examples are known, but popular ones include R = Me and R = Et. They are disulfides obtained by oxidation of the dithiocarbamates. These compounds are used in sulfur vulcanization of rubber as well as in the manufacture of pesticides and drugs. They are typically white or pale yellow solids that are soluble in organic solvents.
Eyelid dermatitis is commonly related to atopic dermatitis or allergic contact dermatitis. Volatile substances, tosylamide, epoxy hardeners, insect sprays, and lemon peel oil may be implicated, with many cases of eyelid contact dermatitis being caused by substances transferred by the hands to the eyelids.
Iodopropynyl Butyl Carbamate (IPBC) is a water-soluble preservative used globally in the paints & coatings, wood preservatives, personal care, and cosmetics industries. IPBC is a member of the carbamate family of biocides. IPBC was invented in the 1970s and has a long history of effective use as an antifungal technology.
Methyldibromo glutaronitrile (MDBGN) is a widely used preservative.
Nickel allergy is any of several allergic conditions provoked by exposure to the chemical element nickel. Nickel allergy often takes the form of nickel allergic contact dermatitis (Ni-ACD), a form of allergic contact dermatitis (ACD). Ni-ACD typically causes a rash that is red and itchy and that may be bumpy or scaly. The main treatment for it is avoiding contact with nickel-releasing metals, such as inexpensive jewelry. Another form of nickel allergy is a systemic form: systemic nickel allergy syndrome (SNAS) can mimic some of the symptoms of irritable bowel syndrome (IBS) and also has a dermatologic component.
Lip licker's dermatitis is a type of skin inflammation around the lips due to damage by saliva from repetitive lip licking and is classified as a subtype of irritant contact cheilitis. The resulting scaling, redness, chapping, and crusting makes a well-defined ring around the lips. The rash may extend as far as the tongue can reach and usually does not occur at the corners of the mouth. It commonly occurs during winter months but some people can have it year-round if lip licking is a chronic habit.
Disperse blue dyes are blue-colored disperse dyes. Disperse dyes are used to color textiles. Disperse blue dyes are used to produce blue and other dark colors. Like other disperse dyes, they are only slightly soluble in water. However, they can be a source of water pollution.
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