Anne W. Rimoin | |
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Born | c. 1970 (age 53–54) |
Alma mater | Middlebury College (B.A. 1992) UCLA (M.P.H. 1996) Johns Hopkins University (Ph.D. 2003) |
Parent |
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Awards | Middlebury College Alumni Achievement Award, Fellow of the American Society of Tropical Medicine and Hygiene, Johns Hopkins Global Achievement Award |
Scientific career | |
Fields | Epidemiology |
Institutions | UCLA School of Public Health |
Thesis | Diagnosis and treatment of group A beta hemolytic streptococcal pharyngitis in children in low and middle income countries (2003) |
Doctoral advisor | Mark Steinhoff |
Anne Walsh Rimoin (born c. 1970) is an American infectious disease epidemiologist whose research focuses on emerging infectious diseases (EIDs), particularly those that are crossing species from animal to human populations. She is a professor of epidemiology at the UCLA Fielding School of Public Health [1] and Infectious Disease Division of the Geffen School of Medicine and is the Director of the Center for Global and Immigrant Health. She is an internationally recognized expert on the epidemiology of Ebola, human monkeypox, [2] [3] [4] and disease emergence in Central Africa. [5]
Rimoin's parents are Maryann Rimoin and David Rimoin, a Canadian-American physician noted for his contributions to research in the genetics of dwarfism and heritable diseases. [6] Rimoin went on to receive her Bachelor of Arts degree in African History at Middlebury College, her Masters in Public Health at the University of California, Los Angeles (UCLA) Fielding School of Public Health, and her PhD at the Johns Hopkins Bloomberg School of Public Health. She also served as a Peace Corps Volunteer in Benin, West Africa which is where she began her career in public health working on the guinea worm eradication initiative with UNICEF and the Carter Center.
She is a professor of epidemiology at both UCLA's Jonathan and Karin Fielding School of Public Health (FSPH) and the Infectious Disease Division of the David Geffen School of Medicine at UCLA. She is the UCLA Director of the Center for Global and Immigrant Health. Additionally, she is the Founder and Director of the UCLA-DRC Health Research and Training Program. In 2020, she spearheaded the COVID-19 rapid response initiative for the protection and testing of front line workers in Los Angeles and to conduct critical research on SARS-CoV-2 asymptomatic infection, immunity and associated epidemiology.
In 2021 she was appointed as the newly established Gordon–Levin Endowed Chair in Infectious Diseases and Public Health at the UCLA Fielding School of Public Health. She is well known as a strong advocate for global health equity and building research capacity in low resource settings, particularly in sub-Saharan Africa.
Since 2002, Rimoin has been working in the Democratic Republic of Congo, where she founded the UCLA-DRC Health Research and Training program to train U.S. and Congolese epidemiologists to conduct high-impact infectious disease research in low-resource, logistically complex settings. Her research there has yielded several important discoveries including the emergence of monkeypox since the cessation of smallpox vaccination, and novel strains of Simian foamy virus in humans. Her work led to fundamental understanding of the long-term consequence of Ebolavirus infection in the oldest known cohorts of Ebolavirus disease survivors and durability of immune responses to Ebolavirus vaccines in health workers.
She was recently inducted as a Fellow of the American Society of Tropical Medicine and Hygiene. [1]
Rimoin's expertise in emerging infectious disease and science communication have made her a regular subject-expert contributor for local, national and international news media outlets. She has appeared regularly on ABC, NBC, CBS, FOX, the BBC, Bloomberg, CNBC, FOX Business, CNN, and Spectrum News etc. and current affairs programs that include: The 11th Hour with Brian Williams and Real Time with Bill Maher to discuss COVID-19. Dr. Rimoin provided advice on COVID-19 Safety and presented a public service announcement at the 93rd Academy Awards about the importance of getting vaccinated against COVID-19. The segment aired on ABC's pre-Oscars "Into the Spotlight" show.
In print, Rimoin's work has been featured in The New York Times , [7] The Atlantic , [8] Scientific American , [9] Nature [10] and National Geographic as well as more than 100 research articles [11] and book chapters.
Mpox is an infectious viral disease that can occur in humans and other animals. Symptoms include a rash that forms blisters and then crusts over, fever, and swollen lymph nodes. The illness is usually mild, and most of infected individuals recover within a few weeks without treatment. The time from exposure to the onset of symptoms ranges from five to twenty-one days, and symptoms typically last from two to four weeks. However, cases may be severe, especially in children, pregnant women, or people with suppressed immune systems.
The species Bundibugyo ebolavirus is the taxonomic home of one virus, Bundibugyo virus (BDBV), that forms filamentous virions and is closely related to the infamous Ebola virus (EBOV). The virus causes severe disease in humans in the form of viral hemorrhagic fever and is a Select agent, World Health Organization Risk Group 4 Pathogen, National Institutes of Health/National Institute of Allergy and Infectious Diseases Category A Priority Pathogen, Centers for Disease Control and Prevention Category A Bioterrorism Agent, and is listed as a Biological Agent for Export Control by the Australia Group.
The monkeypox virus, is a species of double-stranded DNA virus that causes mpox disease in humans and other mammals. The monkeypox virus is a zoonotic virus belonging to the orthopoxvirus genus, making it closely related to the variola, cowpox, and vaccinia viruses. MPV is oval-shaped with a lipoprotein outer membrane. The genome is approximately 190 kb.
Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after infection. The first symptoms are usually fever, sore throat, muscle pain, and headaches. These are usually followed by vomiting, diarrhoea, rash and decreased liver and kidney function, at which point some people begin to bleed both internally and externally. It kills between 25% and 90% of those infected – about 50% on average. Death is often due to shock from fluid loss, and typically occurs between six and 16 days after the first symptoms appear. Early treatment of symptoms increases the survival rate considerably compared to late start. An Ebola vaccine was approved by the US FDA in December 2019.
In 2014, an outbreak of Ebola virus disease in the Democratic Republic of the Congo (DRC) occurred. Genome sequencing has shown that this outbreak was not related to the 2014–15 West Africa Ebola virus epidemic, but was of the same EBOV species. It began in August 2014 and was declared over in November of that year, after 42 days without any new cases. This is the 7th outbreak there, three of which occurred during the period of Zaire.
The 2018 Équateur province Ebola outbreak occurred in the north-west of the Democratic Republic of the Congo (DRC) from May to July 2018. It was contained entirely within Équateur province, and was the first time that vaccination with the rVSV-ZEBOV Ebola vaccine had been attempted in the early stages of an Ebola outbreak, with a total of 3,481 people vaccinated. It was the ninth recorded Ebola outbreak in the DRC.
Judith Glynn is a Professor of Epidemiology at the London School of Hygiene & Tropical Medicine. She worked on the Karonga Prevention Study on HIV and Tuberculosis in Malawi. She is also a sculptor.
Michael Joseph Ryan is an Irish epidemiologist and former trauma surgeon, specialising in infectious disease and public health. He is executive director of the World Health Organization's Health Emergencies Programme, leading the team responsible for the international containment and treatment of COVID-19. Ryan has held leadership positions and has worked on various outbreak response teams in the field to eradicate the spread of diseases including bacillary dysentery, cholera, Crimean–Congo hemorrhagic fever, Ebola, Marburg virus disease, measles, meningitis, relapsing fever, Rift Valley fever, SARS, and Shigellosis.
Maria DeJoseph Van Kerkhove is an American infectious disease epidemiologist. With a background in high-threat pathogens, Van Kerkhove specializes in emerging and re-emerging infectious diseases and is based in the Health Emergencies Program at the World Health Organization (WHO). She is the technical lead of COVID-19 response and the head of emerging diseases and zoonosis unit at WHO.
Marylyn Martina Addo is a German infectiologist who is a Professor and the German Center for Infection Research (DZIF) Head of Infectious Disease at the University Medical Center Hamburg-Eppendorf. Addo has developed and tested vaccinations that protect people from Ebola virus disease and the MERS coronavirus EMC/2012. She is currently developing a viral vector based COVID-19 vaccine.
Nahid Bhadelia is an American infectious-diseases physician, founding director of Center for Emerging Infectious Diseases Policy and Research (CEID) at Boston University and an associate professor at the Boston University School of Medicine. She served as the Senior Policy Advisor for Global COVID-19 Response on the White House COVID-19 Response Team.
Caitlin M. Rivers is an American epidemiologist who as Senior Scholar at the Johns Hopkins Center for Health Security and assistant professor at the Johns Hopkins Bloomberg School of Public Health, specializing on improving epidemic preparedness. Rivers is currently working on the American response to the COVID-19 pandemic with a focus on the incorporation of infectious disease modeling and forecasting into public health decision making.
Angela Lynn Rasmussen is an American virologist at the Vaccine and Infectious Disease Organization at the University of Saskatchewan in Canada.
Alexandra Louise Phelan is an associate professor at Johns Hopkins Bloomberg School of Public Health and senior scholar at the Johns Hopkins Center for Health Security. She specializes in international legal and policy issues that are related to emerging and reemerging infectious diseases, including upstream drivers of disease emergence like climate change.
Natalie E. Dean is an American biostatistician specializing in infectious disease epidemiology. Dean is currently an assistant professor of Biostatistics at the University of Florida. Her research involves epidemiological modeling of outbreaks, including Ebola, Zika and COVID-19.
In August–November 1976, an outbreak of Ebola virus disease occurred in Zaire. The first recorded case was from Yambuku, a small village in Mongala District, 1,098 kilometres (682 mi) northeast of the capital city of Kinshasa.
Atoltivimab/maftivimab/odesivimab, sold under the brand name Inmazeb, is a fixed-dose combination of three monoclonal antibodies for the treatment of Zaire ebolavirus. It contains atoltivimab, maftivimab, and odesivimab-ebgn and was developed by Regeneron Pharmaceuticals.
Ann Marie Kimball is an American physician. She is known for being the pioneer of electronic disease surveillance for infectious disease outbreaks and pandemics. She is currently a Professor Emerita in the Department of Epidemiology at the University of Washington, a Consulting Fellow at the Chatham House Royal Institute of Foreign Affairs, and was a Strategic Consultant in Global Health at the Rockefeller Foundation. Kimball served as a technical and strategic lead for the Bill and Melinda Gates Foundation infectious disease surveillance strategy formation.
Mpox is endemic in western and central Africa, with the majority of cases occurring in the Democratic Republic of the Congo (DRC), where the disease is reportable. There, the more virulent clade I has been affecting some of the world's poorest and socially excluded communities.