Annexin A3 is a protein that in humans is encoded by the ANXA3 gene. [5] [6]
It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. [7]
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [6]
Annexin is a common name for a group of cellular proteins. They are mostly found in eukaryotic organisms.
Annexin A1, also known as lipocortin I, is a protein that is encoded by the ANXA1 gene in humans.
Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene.
Annexin A5 is a cellular protein in the annexin group. In flow cytometry, annexin V is commonly used to detect apoptotic cells by its ability to bind to phosphatidylserine, a marker of apoptosis when it is on the outer leaflet of the plasma membrane. The function of the protein is unknown; however, annexin A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. These properties have been found by in vitro experiments.
Annexin A6 is a protein that in humans is encoded by the ANXA6 gene.
In enzymology, a glycerophosphoinositol inositolphosphodiesterase (EC 3.1.4.43) is an enzyme that catalyzes the chemical reaction
Annexin A4 is a protein that in humans is encoded by the ANXA4 gene.
Annexin A7 is a protein that in humans is encoded by the ANXA7 gene.
Annexin A11 is a protein that in humans is encoded by the ANXA11 gene.
Lipid phosphate phosphohydrolase 1 also known as phosphatidic acid phosphatase 2a is an enzyme that in humans is encoded by the PPAP2A gene.
60S ribosomal protein L4 is a protein that in humans is encoded by the RPL4 gene.
Annexin A8-like protein 2 is a protein that in humans is encoded by the ANXA8L2 gene.
Alpha-1,3/1,6-mannosyltransferase ALG2 is an enzyme that is encoded by the ALG2 gene. Mutations in the human gene are associated with congenital defects in glycosylation The protein encoded by the ALG2 gene belongs to two classes of enzymes: GDP-Man:Man1GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase and GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase.
Type I inositol-3,4-bisphosphate 4-phosphatase is an enzyme that in humans is encoded by the INPP4A gene.
Inositol-tetrakisphosphate 1-kinase is an enzyme that in humans is encoded by the ITPK1 gene.
Inositol hexakisphosphate kinase 1 is an enzyme that in humans is encoded by the IP6K1 gene.
Diphosphoinositol polyphosphate phosphohydrolase 1 is an enzyme that in humans is encoded by the NUDT3 gene.
Annexin A13 is a protein that in humans is encoded by the ANXA13 gene.
Annexin A9 is a protein that in humans is encoded by the ANXA9 gene.
2',3'-Cyclic-nucleotide 3'-phosphodiesterase also known as CNPase is an enzyme that in humans is encoded by the CNP gene.