Santos signed with the Colorado Rockies as an international free agent on July 2,2015.[1] He spent the 2015 season with the DSL Rockies,going 1–2 with a 0.75 ERA over 24 innings. He split the 2016 season between the DSL and the Boise Hawks,going a combined 6–4 with a 3.87 ERA over 81+⁄3 innings. He spent the 2017 season with the Asheville Tourists, going 9–10 with a 5.39 ERA over 147 innings. He split the 2018 season between Asheville and the Lancaster JetHawks, going a combined 5–13 with a 4.80 ERA over 152 innings. He split the 2019 season between Lancaster and the Hartford Yard Goats, going a combined 6–9 with a 4.53 ERA over 145 innings.[2] Santos played in the Arizona Fall League for the Salt River Rafters following the 2019 season.[3]
The Rockies added him to their 40-man roster after the 2019 season.[4]
On September 1, 2020, Santos was promoted to the major leagues for the first time and he made his debut that day against the San Francisco Giants.
New York Mets
The New York Mets claimed Santos off waivers on November 24, 2021. On March 13, 2022, he was removed from the 40-man roster and sent outright to the Triple-A Syracuse Mets.[5] In 29 games split between Syracuse and the Double–A Binghamton Rumble Ponies, Santos accumulated a 4–3 record and 5.74 ERA with 43 strikeouts in 42+1⁄3 innings pitched. He elected free agency following the season on November 10.[6]
On December 11, 2023, Santos signed with the Pericos de Puebla of the Mexican League.[9] In 4 starts for Puebla, Santos compiled a 2.49 ERA with 25 strikeouts across 21+2⁄3 innings pitched.
Chicago Cubs
On May 6, 2024, Santos' contract was purchased by the Chicago Cubs organization.[10]
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