Arsenamide

Last updated
Arsenamide
Arsenamide.png
Names
Preferred IUPAC name
2,2′-{[(4-Carbamoylphenyl)arsanediyl]bis(sulfanediyl)}diacetic acid
Other names
Thiacetarsamide
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
UNII
  • InChI=1S/C11H12AsNO5S2/c13-11(18)7-1-3-8(4-2-7)12(19-5-9(14)15)20-6-10(16)17/h1-4H,5-6H2,(H2,13,18)(H,14,15)(H,16,17) X mark.svgN
    Key: YBQWEUNEYYXYOI-UHFFFAOYSA-N X mark.svgN
  • InChI=1/C11H12AsNO5S2/c13-11(18)7-1-3-8(4-2-7)12(19-5-9(14)15)20-6-10(16)17/h1-4H,5-6H2,(H2,13,18)(H,14,15)(H,16,17)
    Key: YBQWEUNEYYXYOI-UHFFFAOYAK
  • O=C(N)c1ccc(cc1)[As](SCC(=O)O)SCC(=O)O
Properties
C11H12AsNO5S2
Molar mass 377.27 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
X mark.svgN  verify  (what is  Yes check.svgYX mark.svgN ?)

Arsenamide or thiacetarsamide (trade name Caparsolate) is an arsenical. [1] It is a proposed chemotherapeutic agent against canine filaria and trichomonas. [2]

Related Research Articles

<i>Ardipithecus</i> Extinct genus of hominins

Ardipithecus is a genus of an extinct hominine that lived during the Late Miocene and Early Pliocene epochs in the Afar Depression, Ethiopia. Originally described as one of the earliest ancestors of humans after they diverged from the chimpanzees, the relation of this genus to human ancestors and whether it is a hominin is now a matter of debate. Two fossil species are described in the literature: A. ramidus, which lived about 4.4 million years ago during the early Pliocene, and A. kadabba, dated to approximately 5.6 million years ago. Initial behavioral analysis indicated that Ardipithecus could be very similar to chimpanzees, however more recent analysis based on canine size and lack of canine sexual dimorphism indicates that Ardipithecus was characterised by reduced aggression, and that they more closely resemble bonobos.

<span class="mw-page-title-main">Akita (dog)</span> Dog breed

The Akita is a Japanese dog breed of large size. Originating from the mountains of northern Japan, the Akita has a short double coat similar to that of many other northern spitz breeds. Historically, they were used by matagi for guarding and the hunting of bears.

<span class="mw-page-title-main">Canine distemper</span> Viral disease affecting some mammals

Canine distemper virus (CDV) is a viral disease that affects a wide variety of mammal families, including domestic and wild species of dogs, coyotes, foxes, pandas, wolves, ferrets, skunks, raccoons, and felines, as well as pinnipeds, some primates, and a variety of other species. CDV does not affect humans.

<span class="mw-page-title-main">Dentition</span> Development and arrangement of teeth

Dentition pertains to the development of teeth and their arrangement in the mouth. In particular, it is the characteristic arrangement, kind, and number of teeth in a given species at a given age. That is, the number, type, and morpho-physiology of the teeth of an animal.

<i>Smilodon</i> Extinct genus of saber-toothed cat

Smilodon is a genus of felids belonging to the extinct subfamily Machairodontinae. It is one of the best known saber-toothed predators and prehistoric mammals. Although commonly known as the saber-toothed tiger, it was not closely related to the tiger or other modern cats. Smilodon lived in the Americas during the Pleistocene epoch. The genus was named in 1842 based on fossils from Brazil; the generic name means "scalpel" or "two-edged knife" combined with "tooth". Three species are recognized today: S. gracilis, S. fatalis, and S. populator. The two latter species were probably descended from S. gracilis, which itself probably evolved from Megantereon. The hundreds of specimens obtained from the La Brea Tar Pits in Los Angeles constitute the largest collection of Smilodon fossils.

<span class="mw-page-title-main">Canine tooth</span> Long pointed tooth in mammals

In mammalian oral anatomy, the canine teeth, also called cuspids, dog teeth, eye teeth, vampire teeth, or vampire fangs, are the relatively long, pointed teeth. In the context of the upper jaw, they are also known as fangs. They can appear more flattened however, causing them to resemble incisors and leading them to be called incisiform. They developed and are used primarily for firmly holding food in order to tear it apart, and occasionally as weapons. They are often the largest teeth in a mammal's mouth. Individuals of most species that develop them normally have four, two in the upper jaw and two in the lower, separated within each jaw by incisors; humans and dogs are examples. In most species, canines are the anterior-most teeth in the maxillary bone. The four canines in humans are the two upper maxillary canines and the two lower mandibular canines. They are specially prominent in dogs (Canidae), hence the name.

<span class="mw-page-title-main">Frank Rowlett</span> American cryptographer (1908–1998)

Frank Byron Rowlett was an American cryptologist.

<span class="mw-page-title-main">Musical canine freestyle</span> Dog sport

Musical canine freestyle, also known as musical freestyle, freestyle dance, and canine freestyle, is a modern dog sport that is a mixture of obedience training, tricks, and dance that allows for creative interaction between dogs and their owners. The sport has developed into competition forms in several countries around the world.

<span class="mw-page-title-main">Dobermann</span> Black and tan dog breed from Germany

The Dobermann is a German breed of medium-large domestic dog of pinscher type. It was originally bred in Thuringia in about 1890 by Louis Dobermann, a tax collector. It has a long muzzle and – ideally – an even and graceful gait. The ears were traditionally cropped and the tail docked, practices which are now illegal in many countries.

<i>Sander</i> (fish) Genus of fishes

Sander is a genus of predatory ray-finned fish in the family Percidae, which also includes the perches, ruffes, and darters. They are also known as "pike-perch" because of their resemblance to fish in the unrelated Esocidae (pike) family. They are the only genus in the monotypic tribe Luciopercini, which is one of two tribes in the subfamily Luciopercinae,

<span class="mw-page-title-main">Canine coronavirus</span> Species of virus

Canine coronavirus (CCoV) is an enveloped, positive-sense, single-stranded RNA virus which is a member of the species Alphacoronavirus 1. It causes a highly contagious intestinal disease worldwide in dogs. The infecting virus enters its host cell by binding to the APN receptor. It was discovered in 1971 in Germany during an outbreak in sentry dogs. The virus is a member of the genus Alphacoronavirus and subgenus Tegacovirus.

Therianthropy is the mythological ability or affliction of individuals to metamorphose into animals or hybrids by means of shapeshifting. It is possible that cave drawings found at Cave of the Trois-Frères, in France, depict ancient beliefs in the concept.

<span class="mw-page-title-main">WVTK</span> Radio station in Port Henry, New York

WVTK is an FM radio station airing a classic hits radio format, licensed to Port Henry, New York, near the New York State/Vermont border. It is owned by Vox AM/FM, LLC.

<span class="mw-page-title-main">True's shrew mole</span> Species of mammal

True's shrew mole is a species of mammal in the family Talpidae. It is endemic to Japan and is a common species above 1000 meters in grassland, shrubland and forest. Sometimes this species is called the lesser Japanese shrew mole and another species, Urotrichus talpoides, is called the "greater Japanese shrew mole".

<i>Microgomphodon</i> Genus of therapsid from the Middle Triassic of southern Africa

Microgomphodon is an extinct genus of therocephalian therapsid from the Middle Triassic of South Africa and Namibia. Currently only one species of Microgomphodon, M. oligocynus, is recognized. With fossils present in the Cynognathus Assemblage Zone (CAZ) of the Burgersdorp Formation in South Africa and Omingonde Formation of Namibia and ranging in age from late Olenekian to Anisian, it is one of the most geographically and temporally widespread therocephalian species. Moreover, its occurrence in the upper Omigonde Formation of Namibia makes Microgomphodon the latest-surviving therocephalian. Microgomphodon is a member of the family Bauriidae and a close relative of Bauria, another South African bauriid from the CAZ. Like other bauriids, it possesses several mammal-like features such as a secondary palate and broad, molar-like postcanine teeth, all of which evolved independently from mammals.

<i>Isle of Dogs</i> (film) 2018 film by Wes Anderson

Isle of Dogs is a 2018 stop-motion animated comedy film written, produced, and directed by Wes Anderson, narrated by Courtney B. Vance, and starring an ensemble cast that consists of Bryan Cranston, Koyu Rankin, Edward Norton, Liev Schreiber, Bill Murray, Bob Balaban, Jeff Goldblum, Scarlett Johansson, Kunichi Nomura, Tilda Swinton, Ken Watanabe, Akira Ito, Greta Gerwig, Akira Takayama, Frances McDormand, F. Murray Abraham, Yojiro Noda, Fisher Stevens, Mari Natsuki, Nijiro Murakami, Yoko Ono, Harvey Keitel, and Frank Wood. A U.S.–German co-production, Isle of Dogs was produced by Indian Paintbrush and Anderson's own American Empirical Pictures, in association with Studio Babelsberg. The film is set in the fictional Japanese city of Megasaki where Mayor Kenji Kobayashi has banished all dogs to Trash Island due to a canine influenza pandemic. Kobayashi's nephew Atari sets out to find his missing dog Spots with the help of a group of dogs led by stray dog Chief.

Proteopithecidae is an extinct family of primates which lived in the Priabonian and probably early Oligocene periods. Fossils that have been found are in the Jebel Qatrani Formation in Egypt. Currently two genera are recognised, each with a single species, those being Proteopithecus sylviae and Serapia eocaena.

Panthera shawi is an extinct prehistoric cat, of which a single canine tooth was excavated in Sterkfontein cave in South Africa by Robert Broom in the 1940s. It is thought to be the oldest known Panthera species in Africa.

References

  1. Arsenamide at PubChem
  2. Nagata, M.; Yamada, K. (1962-03-20). "Caparsolate Sodium in the Treatment of Canine Filariasis". Journal of the Japan Veterinary Medical Association (in Japanese). 15 (3): 94–98. doi: 10.12935/jvma1951.15.94 . ISSN   0446-6454.