Autographa californica multiple nucleopolyhedrovirus | |
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Virus classification | |
(unranked): | Virus |
Class: | Naldaviricetes |
Order: | Lefavirales |
Family: | Baculoviridae |
Genus: | Alphabaculovirus |
Species: | Autographa californica multiple nucleopolyhedrovirus |
Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is a nucleopolyhedrovirus belonging to the family Baculoviridae . [1] It has a double-stranded DNA genome that is 133,894 base pairs in length with 155 ORFs. [2] The virus forms occluded bodies called polyhedra each containing multiple virions. AcMNPV has been shown to infect more than thirty lepidopteran hosts from 10 families. [3]
Virus classification is the process of naming viruses and placing them into a taxonomic system similar to the classification systems used for cellular organisms.
Baculoviridae is a family of viruses. Arthropods, among the most studied being Lepidoptera, Hymenoptera and Diptera, serve as natural hosts. Currently, 85 species are placed in this family, assigned to four genera.
The International Committee on Taxonomy of Viruses (ICTV) authorizes and organizes the taxonomic classification of and the nomenclature for viruses. The ICTV develops a universal taxonomic scheme for viruses, and thus has the means to appropriately describe, name, and classify every virus taxon. The members of the International Committee on Taxonomy of Viruses are considered expert virologists. The ICTV was formed from and is governed by the Virology Division of the International Union of Microbiological Societies. Detailed work, such as identifying new taxa and delimiting the boundaries of species, genera, families, etc. typically is performed by study groups of experts in the families.
Nudiviruses are a family of animal viruses that constitute the family Nudiviridae. Insects and marine crustaceans serve as natural hosts. There are 11 species in this family, assigned to 4 genera. Diseases associated with this family include: death in larvae, chronic disease in adults.
Autographa californica, the alfalfa looper, is a moth of the family Noctuidae. The species was first described by Adolph Speyer in 1875. It is found in western North America from southern British Columbia to Baja California and to Manitoba, South Dakota, Colorado and New Mexico.
Hytrosaviridae is a family of double-stranded DNA viruses that infect insects. The name is derived from Hytrosa, sigla from the Greek Hypertrophia for 'hypertrophy' and 'sialoadenitis' for 'salivary gland inflammation.'
The PiggyBac (PB) transposon is a mobile genetic element that efficiently transposes between vectors and chromosomes via a "cut and paste" mechanism. During transposition, the PB transposase recognizes transposon-specific inverted terminal repeat sequences (ITRs) located on both ends of the transposon vector and efficiently moves the contents from the original sites and integrates them into TTAA chromosomal sites. The powerful activity of the PiggyBac transposon system enables genes of interest between the two ITRs in the PB vector to be easily mobilized into target genomes. The TTAA-specific transposon piggyBac is rapidly becoming a highly useful transposon for genetic engineering of a wide variety of species, particularly insects. They were discovered in 1989 by Malcolm Fraser at the University of Notre Dame.
Lymantria dispar multicapsid nuclear polyhedrosis virus or LdMNPV is a viral infection in spongy moths that causes infected larvae to die and disintegrate. Infected larvae climb to the top of a tree and die. The larvae then melt or disintegrate, falling onto the foliage below, where they infect more larvae.
V-cath endopeptidase is an enzyme. This enzyme catalyses the following chemical reaction
Quaranjavirus is a genus of enveloped RNA viruses, one of seven genera in the virus family Orthomyxoviridae. The genome is single-stranded, negative-sense segmented RNA, generally with six segments. The genus contains two species: Johnston Atoll virus and Quaranfil virus; it has been proposed to contain species or strains including Cygnet River virus, Lake Chad virus, Tyulek virus and Wellfleet Bay virus. Quaranjaviruses predominantly infect arthropods and birds; As of March 2015, Quaranfil quaranjavirus is the only member of the genus to have been shown to infect humans. The Quaranfil and Johnston Atoll viruses are transmitted between vertebrates by ticks, resembling members of Thogotovirus, another genus of Orthomyxoviridae.
The Early 35 kDa protein, or P35 in short, is a baculoviral protein that inhibits apoptosis in the cells infected by the virus. Although baculoviruses infect only invertebrates in nature, ectopic expression of P35 in vertebrate animals and cells also results in inhibition of apoptosis, thus indicating a universal mechanism. P35 has been shown to be a caspase inhibitor with a very wide spectrum of activity both in regard to inhibited caspase types and to species in which the mechanism is conserved.
Alphabaculovirus is a genus of viruses in the family Baculoviridae. The natural hosts of species in this family are invertebrates, among them winged insects, and decapods. However, species in this genus have been isolated only from the insect order Lepidoptera. There are 56 species in the genus.
Deltabaculovirus is a genus of viruses, in the family Baculoviridae. Mosquito larvae serve as natural hosts. There is only one species in this genus: Culex nigripalpus nucleopolyhedrovirus.
Gammabaculovirus is a genus of viruses, in the family Baculoviridae. Hymenoptera serve as natural hosts. There are two species in this genus.
Perina nuda, the clearwing tussock moth or banyan tussock moth, is a moth of the family Erebidae. The species was first described by Johan Christian Fabricius in 1787. It is found in the Indian subregion, Sri Lanka, to southern China Hong Kong, Thailand and Sundaland.
Metavirus is a genus of viruses in the family Metaviridae. They are retrotransposons that invade a eukaryotic host genome and may only replicate once the virus has infected the host. These genetic elements exist to infect and replicate in their host genome and are derived from ancestral elements unrelated from their host. Metavirus may use several different hosts for transmission, and has been found to be transmissible through ovule and pollen of some plants.
Alphaabyssovirus is a genus of positive-strand RNA viruses in the order Nidovirales which infect sea hares. The genus is monotypic. It contains only the subgenus Aplyccavirus, which contains only one species, Aplysia abyssovirus 1. Alphaabyssovirus is also the only member of the subfamily Tiamatvirinae, which in turn is the only member of family Abyssoviridae, which likewise is the only member of the Abnidovirineae suborder. Aplysia abyssovirus 1 was first isolated from a sample from a California sea hare.
Redondoviruses are a family of human-associated DNA viruses. Their name derives from the inferred circular structure of the viral genome . Redondoviruses have been identified in DNA sequence based surveys of samples from humans, primarily samples from the oral cavity and upper airway.
Helicoverpa zea nudivirus 2 is an enveloped, rod-shaped, nonoccluded, double stranded DNA (dsDNA) sexually transmitted virus whose natural host is the corn earworm moth. At about 440 by 90 nm, it is the causative agent of the only sexually transmitted viral disease of any insect. It was originally identified in a colony of corn earworm moths established and maintained in Stoneville, Mississippi, U.S. and was found to be responsible for the sterility of those infected.
Max Duane Summers is an American molecular biologist and inventor, known for his work on the Baculovirus Expression Vector System (BEVS).