BAZ2A

BAZ2A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4LZ2, 4Q6F, 4QBM, 4QF2, 5AGQ
Identifiers
Aliases	BAZ2A , TIP5, WALp3, bromodomain adjacent to zinc finger domain 2A
External IDs	OMIM: 605682 MGI: 2151152 HomoloGene: 8393 GeneCards: BAZ2A
Gene location (Human)
Chr.	Chromosome 12 (human)
End	56,636,816 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	127,965,172 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; gastric mucosa; ; bone marrow cells; ; right uterine tube; ; right lobe of thyroid gland; ; body of pancreas; ; right lung; ; left lobe of thyroid gland; ; thymus; ; vagina;
	Top expressed in
	female urethra; ; blood; ; hair follicle; ; lymph node; ; secondary oocyte; ; thymus; ; cumulus cell; ; renal corpuscle; ; ciliary body; ; epithelium of stomach;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding ; RNA polymerase I core promoter sequence-specific DNA binding ; histone binding ; metal ion binding ; protein binding ; nuclear receptor binding ; lysine-acetylated histone binding ; RNA binding ;
Cellular component	rDNA heterochromatin ; chromatin silencing complex ; nucleolus ; nucleus ; cytosol ; nuclear speck ;
Biological process	chromatin remodeling ; regulation of transcription, DNA-templated ; transcription, DNA-templated ; DNA methylation ; rDNA heterochromatin assembly ; histone deacetylation ; RNA polymerase I preinitiation complex assembly ; chromatin organization ;
	Sources:Amigo / QuickGO
Orthologs
	11176
	116848
	ENSG00000076108
	ENSMUSG00000040054
	Q9UIF9
	Q91YE5
	NM_001300905 ; NM_013449 ; NM_001351156
	NM_054078
	NP_001287834 ; NP_038477 ; NP_001338085
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 02, 2023

Bromodomain adjacent to zinc finger domain protein 2A is a protein that in humans is encoded by the BAZ2A gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000076108 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040054 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Jones MH, Hamana N, Nezu Ji, Shimane M (Jan 2000). "A novel family of bromodomain genes". Genomics. 63 (1): 40–5. doi:10.1006/geno.1999.6071. PMID 10662543.
↑ Strohner R, Nemeth A, Jansa P, Hofmann-Rohrer U, Santoro R, Längst G, Grummt I (Sep 2001). "NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines". The EMBO Journal. 20 (17): 4892–900. doi:10.1093/emboj/20.17.4892. PMC 125270 . PMID 11532953.
↑ "Entrez Gene: BAZ2A bromodomain adjacent to zinc finger domain, 2A".

External links

Human BAZ2A genome location and BAZ2A gene details page in the UCSC Genome Browser .

Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 4 (2): 141–50. doi: 10.1093/dnares/4.2.141 . PMID 9205841.
Zhou Y, Santoro R, Grummt I (Sep 2002). "The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription". The EMBO Journal. 21 (17): 4632–40. doi:10.1093/emboj/cdf460. PMC 126197 . PMID 12198165.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC 514446 . PMID 15302935.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.
Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M (2007). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biology. 8 (8): R154. doi: 10.1186/gb-2007-8-8-r154 . PMC 2374985 . PMID 17672918.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000076108 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040054 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10662543-5] Jones MH, Hamana N, Nezu Ji, Shimane M (Jan 2000). "A novel family of bromodomain genes". Genomics. 63 (1): 40–5. doi:10.1006/geno.1999.6071. PMID 10662543.

[pmid11532953-6] Strohner R, Nemeth A, Jansa P, Hofmann-Rohrer U, Santoro R, Längst G, Grummt I (Sep 2001). "NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines". The EMBO Journal. 20 (17): 4892–900. doi:10.1093/emboj/20.17.4892. PMC 125270 . PMID 11532953.

[entrez-7] "Entrez Gene: BAZ2A bromodomain adjacent to zinc finger domain, 2A".

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BAZ2A

Contents

Related Research Articles

References

External links

Further reading