Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer. This includes ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. It is given by injection into a vein. There is also an albumin-bound formulation.
Translatio studii is a historiographical concept, originating in the Middle Ages, in which history is viewed as a linear succession of transfers of knowledge or learning from one geographical place and time to another. The concept is closely linked to translatio imperii, which similarly describes the movement of imperial dominance. Both terms are thought to have their origins in the second chapter of the Book of Daniel in the Hebrew Bible.
The Berkeley Pit is a former open pit copper mine located in Butte, Montana, United States. It is 1 mi (1,600 m) long by 1⁄2 mi (800 m) wide with an approximate depth of 1,780 feet (540 m). It is filled to a depth of about 900 feet (270 m) with water that is heavily acidic, about the acidity of Coca-Cola, lemon juice, or gastric acid. As a result, the pit is laden with heavy metals and dangerous chemicals that leach from the rock, including copper, arsenic, cadmium, zinc, and sulfuric acid.
Sonnenbühl is a municipality in the district of Reutlingen, state of Baden-Württemberg, Germany.
5-Bromo-DMT (5-bromo-N,N-dimethyltryptamine) is a psychedelic brominated indole alkaloid found in the sponges Smenospongia aurea and Smenospongia echina, as well as in Verongula rigida alongside 5,6-Dibromo-DMT and seven other alkaloids. It is the 5-bromo derivative of DMT, a psychedelic found in many plants and animals.
The Prix de Lausanne is an international dance competition held annually in Lausanne, Switzerland. The competition is for young dancers seeking to pursue a professional career in classical ballet, and many former prize winners of the competition are now leading stars with major ballet companies around the world. The competition is managed by a non-profit foundation organised by the Fondation en faveur de l'Art chorégraphique and is maintained by various sponsors, patrons and donors.
Stearleyville is an unincorporated community in Jackson Township, Clay County, Indiana.
Oliver Stierle is a German footballer who plays for SV Göppingen.
The Association of Catholic Colleges and Universities (ACCU) is a voluntary association of delegates from Catholic institutions of higher learning.
The American Youth Soccer Organization (AYSO) is one of the two main national organizations in youth soccer in the United States for children aged 4 through 19. AYSO was established as a non-profit soccer organization in Torrance at Jefferson Elementary School in 1964 with nine teams. Today the organization claims membership of over 50,000 teams, with over 630,000 participants.
Vermistatin is an organic compound and a metabolite of mine-dwelling Penicillium vermiculatum found in Berkeley Pit Lake, Butte, Montana. Penisimplicissin is a vermistatin analog with anticancer activity.
Berkeleydione is a chemical compound isolated from a Penicillium species that has in vitro activity in a cancer cell line. It was first discovered in fungal species which evolved to live in an acidic lake at Berkeley Pit.
Berkelic acid is a fungal isolate with anticancer activity in vitro. It was first discovered in the fungal species Euglena Mutabilis, which evolved to live in the Berkeley Pit.
Ubiquitin specific peptidase 22 is a protein that in humans is encoded by the USP22 gene on chromosome 17. USP22 is known to function as a histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA.
Fungal isolates have been researched for decades. Because fungi often exist in thin mycelial monolayers, with no protective shell, immune system, and limited mobility, they have developed the ability to synthesize a variety of unusual compounds for survival. Researchers have discovered fungal isolates with anticancer, antimicrobial, immunomodulatory, and other bio-active properties. The first statins, β-Lactam antibiotics, as well as a few important antifungals, were discovered in fungi.
Penicillium clavigerum is a fungus species of the genus of Penicillium which produces fumigaclavine A and fumigaclavine B
The 2008–09 FC Bayern Munich II season is the first season they participated in the 3. Liga.
Penicillium solitum is an anamorph, mesophilic, salinity-tolerant, psychrotolerant species of fungus in the genus Penicillium which produces polygalacturonase, compactin, cyclopenin, cyclopenol, cyclopeptin, dehydrocompactin, dihydrocyclopeptin, palitantin, solistatin, solistatinol, viridicatin, viridicatol. P. Solitum forms dark blueish green colonies that are 22–28 mm in diameter on Czaek yeast extract and it is brownish orange on malt extract agar. The orange brown color is unique to P. Solitum and can be used to differentiate it from other similar Penicillium species. P. Solitum has been historically isolated in numerous places including on cheese rinds, on cured meats and in the antarctic environment. This species was isolated from air dried lamb thighs, on Faore Island. Penicillium solitum and Eurotium rubrum are the species which are found during the production of traditional produced Tyrolean smoked and cured ham. Penicillium solitum is a pathogen of pomaceous fruit.P. solitum causes blue rot in pome fruits through its production of polygalacturonase, which breaks down the apple’s cell wall.
Montaigne Visiting Torquato Tasso in Prison is an 1821 oil on canvas painting by Fleury François Richard, acquired in 1822 by the Museum of Fine Arts of Lyon at the request of baron Rambaud, mayor of Lyon. It was first exhibited at the Paris Salon of 1822. It is one of the artist's last paintings, showing Torquato Tasso being visited by Montaigne.
The 1766 Istanbul earthquake was a strong earthquake with epicenter in the eastern part of the Sea of Marmara, in the Çınarcık Basin which occurred in the early hours of Thursday morning, 22 May 1766. The earthquake had an estimated magnitude of 7.1 on the surface wave magnitude scale, and caused effects in a vast area extending from Izmit to Rodosto. In this area, the earthquake was followed by a tsunami which caused significant damage. The earthquake of 1766 was the last major earthquake to rock Constantinople because of a rupture of the North Anatolian Fault in the Marmara region.
