Bertha Madras

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Bertha Kalifon Madras is a Canadian professor of psychobiology in the Department of Psychiatry at Harvard University. [1] She also chairs the Division of Neurochemistry at Harvard Medical School, Harvard University. She has worked as associate director for public education in the division on Addictions at Harvard Medical School. Madras's research focuses on drug addiction (particularly the effects of cocaine), ADHD, and Parkinson's disease. [2]

Contents

Madras earned a Bachelor of Science degree in biochemistry with honors from McGill University in 1963. [3] [4] As a J.B. Collop Fellow of the Faculty of Medicine, she earned a PhD in biochemistry (metabolism and pharmacology, including hallucinogens) from McGill University in 1967. [3] [4] She completed postdoctoral fellowships in biochemistry at Tufts University/Cornell University Medical College (1966–1967) as well as at the Massachusetts Institute of Technology (1967–1969). [3] [4]

Madras was appointed a research associate at the Massachusetts Institute of Technology (1972–1974) and an assistant professor in the Departments of Pharmacology and Psychiatry at the University of Toronto. [3] [4] She joined the Harvard Medical School as an assistant professor in 1986 and was subsequently promoted to associate professor, then full professor, with a cross-appointment to the Department of Psychiatry at the Massachusetts General Hospital. [3] Madras also founded and chaired the Division of Neurochemistry at Harvard Medical School's New England Primate Research Center—a multidisciplinary translational research program that spans chemical design, molecular and cellular biology, behavioral biology, and brain imaging approaches. [3] She directs the Laboratory of Addiction Neurobiology, McLean Hospital, in conjunction with the Harvard Brain Science initiative. [5]

Personal life

She is married to Peter Madras. [6] They have two daughters, two sons-in-law, and five grandchildren.[ citation needed ]

Public policy work

Madras served as the Deputy Director for Demand Reduction for the White House Office of National Drug Control Policy (ONDCP). [7] She was nominated by President George W. Bush in July 2005 and unanimously confirmed by the United States Senate in 2006. [8] [9]

During Madras's time in the ONDCP, she was involved in introducing new diagnostic codes for addiction screening and brief intervention (SBI), which were intended to help doctors secure reimbursement for SBI carried out for Medicaid patients. These new diagnostic codes were adopted by ten states in July 2008. [10] A proponent of using SBI for early intervention with addiction, [11] [12] Madras advocated extending insurance coverage for SBI to federal workers covered by the Federal Employees Health Benefits Program; this coverage was announced by the ONDCP in April 2008. [13]

Research

Madras has authored over 130 scientific manuscripts and book chapters. In 2003, she co-edited the book Cell Biology of Addiction. [14] She later co-edited two more books, The Effects of Drug Abuse on the Human Nervous System (2013) and Imaging of the Human Brain in Health and Disease (2013). [15]

In October 2008, Madras and five other researchers published a study on the effect of the federally funded Screening, Brief Intervention, Referral to Treatment (SBIRT) service program on illicit drug use. The study involved various patient populations in six different states over six months. [16]

As of the end of 2024, Madras and her collaborators have been granted nineteen U.S. and twenty-seven international patents. [17] [18]

Honors

Her co-discovery of altropane was recognized by the Association of University Technology Managers in 2006. [19]

References

  1. ↑ Harvard University website, Harvard Catalyst Profiles section, Bertha Kalifon Madras, Ph.D., retrieved January 2, 2025
  2. ↑ "Bertha Madras | Harvard Medical School". hms.harvard.edu. Retrieved February 24, 2025.
  3. 1 2 3 4 5 6 "United States of America v. Schweder, et al. (2014). "Declaration of Bertha Madras, Ph.D". Case No. 2:11-CR-00449-KJM-16, in the United States District Court - Eastern District of California. Page 2" (PDF). Archived (PDF) from the original on April 17, 2018. Retrieved August 8, 2017.
  4. 1 2 3 4 "Bertha K. Madras, PHD | McLean Hospital". Archived from the original on August 8, 2017. Retrieved August 8, 2017.
  5. ↑ "Bertha Madras". Harvard Brain Science Initiative. Archived from the original on August 10, 2022. Retrieved August 10, 2022.
  6. ↑ Newspapers.com website, Bertha Kalifon Weds Peter Madras, article published in the Montreal Gazette, July 9, 1964
  7. ↑ "Bertha Madras, Deputy Director for Demand Reduction, White House Office of National Drug Control Policy - ONDCP". Archived from the original on August 7, 2007. Retrieved 2008-01-15.
  8. ↑ "Office of National Drug Control Policy | The White House". Whitehousedrugpolicy.gov. Archived from the original on May 16, 2008. Retrieved October 19, 2011.
  9. ↑ George W. Bush White House Archives website, Bertha Kalifon Madras
  10. ↑ SBI Codes Adopted by 10 States, Join Together, Boston University School of Public Health, July 8, 2008, archived from the original on October 18, 2008
  11. ↑ "National strategy focuses on screening: ONDCP demand reduction chief urges early intervention. (Office of National Drug Control Policy)". Alcoholism & Drug Abuse Weekly. February 19, 2007. doi:10.1002/adaw.20078.
  12. ↑ Bertha K. Madras: Office of National Drug Control Policy: A scientist in drug policy in Annals of the New York Academy of Sciences, 1187: Addiction Reviews 2; pages 370–402, 2010.
  13. ↑ Whyche, Stephanie (May 16, 2008). "Federal Workers Get Coverage for Substance Abuse Screening". Psychiatry Online. doi:10.1176/pn.43.10.0004. Archived from the original on February 4, 2025. Retrieved February 4, 2025.
  14. ↑ Madras BK. Introduction to "Cell Biology of Addiction". Editors: Madras BK, Colvis CM, Pollack JD, Rutter JL, Shurtleff D, von Zastrow M, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp 1–12, 2006.
  15. ↑ McLean Hospital website, Bertha K. Madras, PhD
  16. ↑ Madras, BK; Compton, WM; Avula, D; Stegbauer, T; Stein, JB; Clark, HW (January 2009). "Screening, brief interventions, referral to treatment (SBIRT) for illicit drug and alcohol use at multiple healthcare sites: comparison at intake and 6 months later". Drug Alcohol Depend. 99 (1–3): 280–95. doi:10.1016/j.drugalcdep.2008.08.003. PMC   2760304 . PMID   18929451.
  17. ↑ American Academy of Sciences and Letters website, Bertha Kalifon Madras, article dated October 1, 2024
  18. ↑ "United States Patent and Trademark Office". Uspto.gov. December 1, 1994. Archived from the original on February 1, 2018. Retrieved October 19, 2011.
  19. ↑ "Business And Career Training Courses". certificationacademy.com. Retrieved December 6, 2024.

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