CALCOCO1

CALCOCO1
Identifiers
Aliases	CALCOCO1 , Cocoa, calphoglin, PP13275, calcium binding and coiled-coil domain 1
External IDs	MGI: 1914738; HomoloGene: 10845; GeneCards: CALCOCO1; OMA:CALCOCO1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.13 Start 53,708,517 bp [1] End 53,727,745 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15 F3|15 Start 102,615,212 bp [2] End 102,630,613 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastric mucosa skin of leg Descending thoracic aorta right hemisphere of cerebellum popliteal artery tibial arteries skin of abdomen right coronary artery ascending aorta muscle layer of sigmoid colon Top expressed in ascending aorta genital tubercle zygote lip muscle of thigh aortic valve interventricular septum neural layer of retina esophagus dentate gyrus of hippocampal formation granule cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function sequence-specific DNA binding beta-catenin binding transcription coactivator activity chromatin binding transcription coregulator activity protein C-terminus binding protein binding nuclear receptor coactivator activity armadillo repeat domain binding RNA polymerase II cis-regulatory region sequence-specific DNA binding Cellular component intracellular membrane-bounded organelle nucleus cytoplasm cytosol Biological process regulation of transcription, DNA-templated intracellular steroid hormone receptor signaling pathway Wnt signaling pathway transcription, DNA-templated positive regulation of transcription, DNA-templated signal transduction positive regulation of transcription by RNA polymerase II positive regulation of gene expression Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57658 67488 Ensembl ENSG00000012822 ENSMUSG00000023055 UniProt Q9P1Z2 Q8CGU1 RefSeq (mRNA) NM_001143682 NM_020898 NM_026192 RefSeq (protein) NP_001137154 NP_065949 NP_080468 Location (UCSC) Chr 12: 53.71 – 53.73 Mb Chr 15: 102.62 – 102.63 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Calcium-binding and coiled-coil domain-containing protein 1 is a protein that in humans is encoded by the CALCOCO1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000012822 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000023055 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi: 10.1093/dnares/7.2.143 . PMID   10819331.
6. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
7. "Entrez Gene: CALCOCO1 calcium binding and coiled-coil domain 1".

External links

• Human CALCOCO1 genome location and CALCOCO1 gene details page in the UCSC Genome Browser .

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Lee SY, Obata Y, Yoshida M, et al. (2003). "Immunomic analysis of human sarcoma". Proc. Natl. Acad. Sci. U.S.A. 100 (5): 2651–6. Bibcode:2003PNAS..100.2651L. doi: 10.1073/pnas.0437972100 . PMC   151395 . PMID   12601173.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Takahashi K, Inuzuka M, Ingi T (2005). "Cellular signaling mediated by calphoglin-induced activation of IPP and PGM". Biochem. Biophys. Res. Commun. 325 (1): 203–14. doi:10.1016/j.bbrc.2004.10.021. PMID   15522220.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Yang CK, Kim JH, Li H, Stallcup MR (2006). "Differential use of functional domains by CoCoA in its synergistic coactivator function with β-catenin or GRIP1". J. Biol. Chem. 281 (6): 3389–97. doi: 10.1074/jbc.M510403200 . PMC   1626527 . PMID   16344550.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi: 10.1016/j.cell.2006.03.032 . PMID   16713569. S2CID   13709685.
• Yang CK, Kim JH, Stallcup MR (2007). "Role of the N-terminal activation domain of coactivator CoCoA in mediating transcriptional activation by β-catenin". Mol. Endocrinol. 20 (12): 3251–62. doi:10.1210/me.2006-0200. PMC   1770943 . PMID   16931570.