Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene. [4] [5] [6]
The protein encoded by this gene is related to the Saccharomyces cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. [6]
CAP1 has been shown to interact with ACTG1 [7] and CAP2. [5]
Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene.
Adenylyl cyclase type 6 is an enzyme that in humans is encoded by the ADCY6 gene.
Drebrin is a protein that in humans is encoded by the DBN1 gene.
Dynamin-3 is a protein that in humans is encoded by the DNM3 gene. The protein encoded by this gene is a member of the dynamin family which possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding. DNM3 is upregulated in Sézary's syndrome.
Protein SEC13 homolog is a protein that in humans is encoded by the SEC13 gene.
Adenylyl cyclase type 2 is an enzyme typically expressed in the brain of humans, that is encoded by the ADCY2 gene. It belongs to the adenylyl cyclase class-3 or guanylyl cyclase family because it contains two guanylate cyclase domains. ADCY2 is one of ten different mammalian isoforms of adenylyl cyclases. ADCY2 can be found on chromosome 5 and the "MIR2113-POU3F2" region of chromosome 6, with a length of 1091 amino-acids. An essential cofactor for ADCY2 is magnesium; two ions bind per subunit.
Adenylyl cyclase type 7 is an enzyme that in humans is encoded by the ADCY7 gene.
Adenylyl cyclase type 9 is an enzyme that in humans is encoded by the ADCY9 gene.
Resistance to inhibitors of cholinesterase-8A (Ric-8A), also known as Synembryn-A, is a protein that in humans is encoded by the RIC8A gene.
Adenylyl cyclase type 8 is an enzyme that in humans is encoded by the ADCY8 gene.
Scinderin is a protein that in humans is encoded by the SCIN gene. Scinderin is an actin severing protein belonging to the gelsolin superfamily. It was discovered in Dr. Trifaro's laboratory at the University of Ottawa, Canada. Secretory tissues are rich in scinderin. In these tissues scinderin, a calcium dependent protein, regulates cortical actin networks. Normally secretory vesicles are excluded from release sites on the plasma membrane by the presence of a cortical actin filament network. During cell stimulation, calcium channels open allowing calcium ions to enter the secretory cell. Increase in intracellular calcium activates scinderin with the consequent actin filament severing and local dissociation of actin filament networks. This allows the movement of secretory vesicles to release sites on the plasma membrane.
RNA 3'-terminal phosphate cyclase-like protein is an enzyme that in humans is encoded by the RCL1 gene.
Coronin-1C is a protein that in humans is encoded by the CORO1C gene.
60S ribosomal protein L13 is a protein that in humans is encoded by the RPL13 gene.
Actin-related protein 2/3 complex subunit 1A is a protein that in humans is encoded by the ARPC1A gene.
Guanine nucleotide-binding protein G(olf) subunit alpha is a protein that in humans is encoded by the GNAL gene. Its main product is the heterotrimeric G-protein alpha subunit Golf-α, a member of the Gs alpha subunit family that is a key component of G protein-coupled receptor-regulated adenylyl cyclase signal transduction pathways in the olfactory system and the striatum in the brain. It also mediated D1 receptor signalling in the striatum and is hence involved in motor control.
Adenylyl cyclase type 4 is an enzyme that in humans is encoded by the ADCY4 gene.
Serpin B8 is a protein that in humans is encoded by the SERPINB8 gene.
Adenylyl cyclase-associated protein 2 is an enzyme that in humans is encoded by the CAP2 gene.
Adenylyl cyclase 10 also known as ADCY10 is an enzyme that, in humans, is encoded by the ADCY10 gene.
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