CCDC80

CCDC80
Identifiers
Aliases	CCDC80 , DRO1, SSG1, URB, okuribin, coiled-coil domain containing 80, CL2, LINC01279
External IDs	OMIM: 608298 MGI: 1915146 HomoloGene: 12206 GeneCards: CCDC80
Gene location (Human)
Chr.	Chromosome 3 (human)
End	112,649,530 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	45,128,077 bp
RNA expression pattern
	; ;
	More reference expression data
Gene ontology
Molecular function	• fibronectin binding ; • glycosaminoglycan binding ; • heparin binding ;
Cellular component	• extracellular region ; • basement membrane ; • interstitial matrix ; • GO:0005578 extracellular matrix ;
Biological process	• extracellular matrix organization ; • positive regulation of cell-substrate adhesion ; • response to bacterium ;
	Sources:Amigo / QuickGO
Orthologs
	151887
	67896
	ENSG00000091986
	ENSMUSG00000022665
	Q76M96
	Q8R2G6
	NM_199512 ; NM_199511
	NM_026439
	NP_955805 ; NP_955806
	NP_080715
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 23, 2021

Coiled-coil domain-containing protein 80 is a protein that in humans is encoded by the CCDC80 gene.^[5]^[6]^[7] Bioinformatics analysis suggests the CCDC80 protein is a peroxiredoxin.^[8]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000091986 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022665 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Bonaldo MF, Lennon G, Soares MB (May 1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.
↑ Liu Y, Monticone M, Tonachini L, Mastrogiacomo M, Marigo V, Cancedda R, Castagnola P (Aug 2004). "URB expression in human bone marrow stromal cells and during mouse development". Biochem Biophys Res Commun. 322 (2): 497–507. doi:10.1016/j.bbrc.2004.07.161. PMID 15325258.
↑ "Entrez Gene: CCDC80 coiled-coil domain containing 80".
↑ Pawłowski K, Muszewska A, Lenart A, et al. (2010). "A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins". BMC Genomics. 11: 590. doi:10.1186/1471-2164-11-590. PMC 3091736 . PMID 20964819.

External links

Human CCDC80 genome location and CCDC80 gene details page in the UCSC Genome Browser .

Okada T, Nishizawa H, Kurata A, et al. (2008). "URB is abundantly expressed in adipose tissue and dysregulated in obesity". Biochem. Biophys. Res. Commun. 367 (2): 370–6. doi:10.1016/j.bbrc.2007.12.164. PMID 18178152.
Cha SY, Sung YK, Im S, et al. (2005). "URB expression in human dermal papilla cells". J. Dermatol. Sci. 39 (2): 128–30. doi:10.1016/j.jdermsci.2005.05.005. PMID 15998583.
Bommer GT, Jäger C, Dürr EM, et al. (2005). "DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells". J. Biol. Chem. 280 (9): 7962–75. doi: 10.1074/jbc.M412593200 . PMID 15563452.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Aoki K, Sun YJ, Aoki S, et al. (2002). "Cloning, expression, and mapping of a gene that is upregulated in adipose tissue of mice deficient in bombesin receptor subtype-3". Biochem. Biophys. Res. Commun. 290 (4): 1282–8. doi:10.1006/bbrc.2002.6337. PMID 11812002.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000091986 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022665 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8889548-5] Bonaldo MF, Lennon G, Soares MB (May 1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.

[pmid15325258-6] Liu Y, Monticone M, Tonachini L, Mastrogiacomo M, Marigo V, Cancedda R, Castagnola P (Aug 2004). "URB expression in human bone marrow stromal cells and during mouse development". Biochem Biophys Res Commun. 322 (2): 497–507. doi:10.1016/j.bbrc.2004.07.161. PMID 15325258.

[entrez-7] "Entrez Gene: CCDC80 coiled-coil domain containing 80".

[pmid20964819-8] Pawłowski K, Muszewska A, Lenart A, et al. (2010). "A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins". BMC Genomics. 11: 590. doi:10.1186/1471-2164-11-590. PMC 3091736 . PMID 20964819.

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CCDC80

Contents

Related Research Articles

References

External links

Further reading