CDC42EP1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | CDC42EP1 , BORG5, CEP1, MSE55, CDC42 effector protein 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 606084 MGI: 1929763 HomoloGene: 5128 GeneCards: CDC42EP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Cdc42 effector protein 1 is a protein that in humans is encoded by the CDC42EP1 gene. [5] [6] [7]
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. The encoded protein, which is secreted, is primarily found in bone marrow. Two transcript variants encoding different isoforms have been found for this gene. [7]
Cdc42-interacting protein 4 is a protein that in humans is encoded by the TRIP10 gene.
Rho-related GTP-binding protein RhoQ is a protein that in humans is encoded by the RHOQ gene.
Chimerin 2 (beta-chimaerin) is a protein that in humans is encoded by the CHN2 gene.
Serine/threonine-protein kinase MRCK alpha is an enzyme that in humans is encoded by the CDC42BPA gene.
Cdc42 effector protein 3 is a protein that in humans is encoded by the CDC42EP3 gene.
Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene.
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 is a protein that in humans is encoded by the BNIP2 gene.
Rho GTPase activating protein 26 (ARHGAP26) also known as GTPase Regulator Associated with Focal Adhesion Kinase (GRAF) is a protein that in humans is encoded by the ARHGAP26 gene.
Formin-binding protein 1-like is a protein that in humans is encoded by the FNBP1L gene.
SLIT-ROBO Rho GTPase-activating protein 3 is an enzyme that in humans is encoded by the SRGAP3 gene.
TC10/CDC42 GTPase-activating protein is an enzyme that in humans is encoded by the SNX26 gene.
TBC1 domain family member 3E/3F is a protein that in humans is encoded by the TBC1D3F gene.
Disheveled-associated activator of morphogenesis 1 is a protein that in humans is encoded by the DAAM1 gene. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.
Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene.
Rho GTPase-activating protein 8 is a protein that in humans is encoded by the ARHGAP8 gene.
Cdc42 effector protein 2 is a protein that in humans is encoded by the CDC42EP2 gene.
FYVE, RhoGEF and PH domain-containing protein 4 is a protein that in humans is encoded by the FGD4 gene.
Rho-related GTP-binding protein RhoJ is a protein that in humans is encoded by the RHOJ gene.
FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans is encoded by the FGD2 gene.
The Rho GTPase activating protein 31 is encoded in humans by the ARHGAP31 gene. It is a Cdc42/Rac1 GTPase regulator.