CHST12

CHST12
Identifiers
Aliases	CHST12 , C4S-2, C4ST-2, C4ST2, carbohydrate (chondroitin 4) sulfotransferase 12, carbohydrate sulfotransferase 12
External IDs	OMIM: 610129; MGI: 1929064; HomoloGene: 69258; GeneCards: CHST12; OMA:CHST12 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7p22.3 Start 2,403,588 bp [1] End 2,448,484 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5|5 G2 Start 140,491,305 bp [2] End 140,511,479 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell secondary oocyte cerebellar vermis granulocyte synovial joint stromal cell of endometrium apex of heart spleen blood bone marrow cell Top expressed in granulocyte decidua interventricular septum ankle calvaria umbilical cord lumbar spinal ganglion stroma of bone marrow white adipose tissue yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity sulfotransferase activity 3'-phosphoadenosine 5'-phosphosulfate binding chondroitin 4-sulfotransferase activity Cellular component integral component of membrane integral component of Golgi membrane Golgi membrane Golgi apparatus membrane Biological process chondroitin sulfate biosynthetic process dermatan sulfate biosynthetic process carbohydrate biosynthetic process carbohydrate metabolic process proteoglycan biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55501 59031 Ensembl ENSG00000136213 ENSMUSG00000036599 UniProt Q9NRB3 Q99LL3 RefSeq (mRNA) NM_001243794 NM_001243795 NM_018641 NM_021528 RefSeq (protein) NP_001230723 NP_001230724 NP_061111 NP_067503 Location (UCSC) Chr 7: 2.4 – 2.45 Mb Chr 5: 140.49 – 140.51 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Carbohydrate sulfotransferase 12 is an enzyme that in humans is encoded by the CHST12 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000136213 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036599 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hiraoka N, Nakagawa H, Ong E, Akama TO, Fukuda MN, Fukuda M (Aug 2000). "Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family". J Biol Chem. 275 (26): 20188–96. doi: 10.1074/jbc.M002443200 . PMID   10781601.
6. "Entrez Gene: CHST12 carbohydrate (chondroitin 4) sulfotransferase 12".

External links

• Human CHST12 genome location and CHST12 gene details page in the UCSC Genome Browser .

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC   2882961 . PMID   12690205.
• Mikami T, Mizumoto S, Kago N, et al. (2003). "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis". J. Biol. Chem. 278 (38): 36115–27. doi: 10.1074/jbc.M306044200 . PMID   12847091.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.