CHST4

Last updated
CHST4
Identifiers
Aliases CHST4 , GST3, GlcNAc6ST2, HECGLCNAC6ST, LSST, carbohydrate sulfotransferase 4
External IDs MGI: 1349479 HomoloGene: 4216 GeneCards: CHST4
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005769
NM_001166395

NM_011998

RefSeq (protein)

NP_001159867
NP_005760

NP_036128

Location (UCSC) Chr 16: 71.53 – 71.54 Mb Chr 8: 110.76 – 110.77 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Carbohydrate sulfotransferase 4 is an enzyme that in humans is encoded by the CHST4 gene. [5] [6]

Contents


Related Research Articles

<span class="mw-page-title-main">CHST6</span> Protein-coding gene in the species Homo sapiens

Carbohydrate sulfotransferase 6 is an enzyme that in humans is encoded by the CHST6 gene.

<span class="mw-page-title-main">GCNT1</span> Protein-coding gene in the species Homo sapiens

Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the GCNT1 gene.

<span class="mw-page-title-main">CHST2</span>

Carbohydrate sulfotransferase 2 is an enzyme that in humans is encoded by the CHST2 gene.

<span class="mw-page-title-main">CHST1</span>

Carbohydrate sulfotransferase 1 is an enzyme that in humans is encoded by the CHST1 gene.

<span class="mw-page-title-main">NDST1</span> Enzyme

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 is an enzyme. In humans, it is encoded by the NDST1 gene.

<span class="mw-page-title-main">NAGPA</span> Protein-coding gene in the species Homo sapiens

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase is an enzyme that in humans is encoded by the NAGPA gene.

<span class="mw-page-title-main">GALNAC4S-6ST</span> Protein-coding gene in the species Homo sapiens

Carbohydrate sulfotransferase 15 is an enzyme that in humans is encoded by the CHST15 gene. It belongs to the N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase enzyme class.

<span class="mw-page-title-main">GAL3ST2</span>

Galactose-3-O-sulfotransferase 2 is an enzyme that in humans is encoded by the GAL3ST2 gene.

<span class="mw-page-title-main">CHST5</span> Protein-coding gene in the species Homo sapiens

Carbohydrate sulfotransferase 5 is an enzyme that in humans is encoded by the CHST5 gene.

<span class="mw-page-title-main">HS3ST3A1</span> Protein-coding gene in the species Homo sapiens

Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 is an enzyme that in humans is encoded by the HS3ST3A1 gene.

<span class="mw-page-title-main">CHST12</span>

Carbohydrate sulfotransferase 12 is an enzyme that in humans is encoded by the CHST12 gene.

<span class="mw-page-title-main">GAL3ST4</span>

Galactose-3-O-sulfotransferase 4 is an enzyme that in humans is encoded by the GAL3ST4 gene.

<span class="mw-page-title-main">NDST2</span> Enzyme

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 is an enzyme that in humans is encoded by the NDST2 gene.

<span class="mw-page-title-main">EXTL2</span> Protein-coding gene in the species Homo sapiens

Exostosin-like 2 is a protein that in humans is encoded by the EXTL2 gene. EXTL2 Glycosyltransferase is required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

<span class="mw-page-title-main">CHST7</span> Protein-coding gene in the species Homo sapiens

Carbohydrate sulfotransferase 7 is an enzyme that in humans is encoded by the CHST7 gene.

<span class="mw-page-title-main">GAL3ST3</span>

Galactose-3-O-sulfotransferase 3 is an enzyme that in humans is encoded by the GAL3ST3 gene.

<span class="mw-page-title-main">NDST3</span> Enzyme

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 is an enzyme that in humans is encoded by the NDST3 gene. It catalyses the reaction:

3'-phosphoadenylyl sulfate + α-D-glucosaminyl-[heparan sulfate](n) = adenosine 3',5'-bisphosphate + 2 H+ + N-sulfo-α-D-glucosaminyl-[heparan sulfate](n)

<span class="mw-page-title-main">CHST10</span>

Carbohydrate sulfotransferase 10 is an enzyme that in humans is encoded by the CHST10 gene.

<span class="mw-page-title-main">Carbohydrate sulfotransferase</span>

Carbohydrate sulfotransferases are sulfotransferase enzymes that transfer sulfate to carbohydrate groups in glycoproteins and glycolipids. Carbohydrates are used by cells for a wide range of functions from structural purposes to extracellular communication. Carbohydrates are suitable for such a wide variety of functions due to the diversity in structure generated from monosaccharide composition, glycosidic linkage positions, chain branching, and covalent modification. Possible covalent modifications include acetylation, methylation, phosphorylation, and sulfation. Sulfation, performed by carbohydrate sulfotransferases, generates carbohydrate sulfate esters. These sulfate esters are only located extracellularly, whether through excretion into the extracellular matrix (ECM) or by presentation on the cell surface. As extracellular compounds, sulfated carbohydrates are mediators of intercellular communication, cellular adhesion, and ECM maintenance.

<span class="mw-page-title-main">ALG14</span> Protein-coding gene in the species Homo sapiens

UDP-N-acetylglucosamine transferase subunit ALG14 homolog is a protein that in humans is encoded by the ALG14 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000140835 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035930 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bistrup A, Bhakta S, Lee JK, Belov YY, Gunn MD, Zuo FR, Huang CC, Kannagi R, Rosen SD, Hemmerich S (Jul 1999). "Sulfotransferases of Two Specificities Function in the Reconstitution of High Endothelial Cell Ligands for L-selectin". J Cell Biol. 145 (4): 899–910. doi:10.1083/jcb.145.4.899. PMC   2133194 . PMID   10330415.
  6. "Entrez Gene: CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4".

Further reading