CLEC2B

Last updated
CLEC2B
Identifiers
Aliases CLEC2B , AICL, CLECSF2, HP10085, IFNRG1, C-type lectin domain family 2 member B
External IDs OMIM: 603242; HomoloGene: 68443; GeneCards: CLEC2B; OMA:CLEC2B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005127

n/a

RefSeq (protein)

NP_005118

n/a

Location (UCSC) Chr 12: 9.85 – 9.87 Mb n/a
PubMed search [2] n/a
Wikidata
View/Edit Human

C-type lectin domain family 2 member B is a protein that in humans is encoded by the CLEC2B gene. [3] [4]

Contents

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) protein superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length nucleotide sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [4]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000110852 Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Hamann J, Montgomery KT, Lau S, Kucherlapati R, van Lier RA (Mar 1997). "AICL: a new activation-induced antigen encoded by the human NK gene complex". Immunogenetics. 45 (5): 295–300. doi:10.1007/s002510050208. PMID   9038101. S2CID   34214844.
  4. 1 2 "Entrez Gene: CLEC2B C-type lectin domain family 2, member B".

Further reading