NAD(P)H dehydrogenase, quinone 2, also known as QR2, is a protein that in humans is encoded by the NQO2 gene. It is a phase II detoxification enzyme which can carry out two or four electron reductions of quinones. Its mechanism of reduction is through a ping-pong mechanism involving its FAD cofactor. Initially in a reductive phase NQO2 binds to reduced dihydronicotinamide riboside (NRH) electron donor, and mediates a hydride transfer from NRH to FAD. Then, in an oxidative phase, NQO2 binds to its quinone substrate and reduces the quinone to a dihydroquinone. Besides the two catalytic FAD, NQO2 also has two zinc ions. It is not clear whether the metal has a catalytic role. NQO2 is a paralog of NQO1.
Beta-crystallin B1 is a protein that in humans is encoded by the CRYBB1 gene. Variants in CRYBB1 are associated with autosomal dominant congenital cataract.
Gamma-crystallin B is a protein that in humans is encoded by the CRYGB gene.
Bardet–Biedl syndrome 5 protein is a protein that in humans is encoded by the BBS5 gene.
Chloride transport protein 6 is a protein that in humans is encoded by the CLCN6 gene.
Olfactory receptor 2F1 is a protein that in humans is encoded by the OR2F1 gene.
RNA exonuclease 4 is an enzyme that in humans is encoded by the REXO4 gene.
Beta-crystallin A4 is a protein that in humans is encoded by the CRYBA4 gene.
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial is an enzyme that in humans is encoded by the NDUFV3 gene.
Putative quinone oxidoreductase is an enzyme that in humans is encoded by the TP53I3 gene.
Quinone oxidoreductase is an enzyme that in humans is encoded by the CRYZ gene.
Dehydrogenase/reductase SDR family member 1, also known as Short chain dehydrogenase/reductase family 19C member 1 is an enzyme that in humans is encoded by the DHRS1 gene located on chromosome 14.
Beta-crystallin B3 is a protein that in humans is encoded by the CRYBB3 gene.
Gamma-crystallin A is a protein that in humans is encoded by the CRYGA gene.
Mu-crystallin homolog also known as NADP-regulated thyroid-hormone-binding protein (THBP) is a protein that in humans is encoded by the CRYM gene. Multiple alternatively spliced transcript variants have been found for this gene.
39S ribosomal protein L39, mitochondrial is a protein that in humans is encoded by the MRPL39 gene.
Synaptic vesicle membrane protein VAT-1 homolog is a protein that in humans is encoded by the VAT1 gene.
Zinc finger protein 33B is a protein that in humans is encoded by the ZNF33B gene.
Zinc finger protein 41 is a protein that in humans is encoded by the ZNF41 gene.
Muscleblind-like protein 2 is a protein that in humans is encoded by the MBNL2 gene.
