CSDC2

CSDC2
Identifiers
Aliases	CSDC2 , PIPPIN, dJ347H13.2, cold shock domain containing C2
External IDs	OMIM: 617689; MGI: 2146027; HomoloGene: 8701; GeneCards: CSDC2; OMA:CSDC2 - orthologs
Gene location (Human) Chr. Chromosome 22 (human) [1] Band 22q13.2 Start 41,561,010 bp [1] End 41,577,741 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 E1 Start 81,820,960 bp [2] End 81,835,142 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart right auricle of heart left ventricle right coronary artery left adrenal cortex right adrenal gland left ovary right adrenal cortex right ovary popliteal artery Top expressed in pontine nuclei medial geniculate nucleus gastrula medial vestibular nucleus medial dorsal nucleus dorsal tegmental nucleus inferior colliculi motor neuron cerebellar cortex cerebellar vermis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding protein binding RNA binding nucleic acid binding mRNA 3'-UTR binding transcription factor binding Cellular component nucleus cytoplasm Biological process mRNA processing regulation of transcription, DNA-templated regulation of mRNA stability Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27254 105859 Ensembl ENSG00000172346 ENSMUSG00000042109 UniProt Q9Y534 Q91YQ3 RefSeq (mRNA) NM_014460 NM_145473 RefSeq (protein) NP_055275 NP_663448 Location (UCSC) Chr 22: 41.56 – 41.58 Mb Chr 15: 81.82 – 81.84 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Cold shock domain-containing protein C2 is a protein that in humans is encoded by the CSDC2 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000172346 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042109 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Castiglia D, Scaturro M, Nastasi T, Cestelli A, Di Liegro I (Mar 1996). "PIPPin, a putative RNA-binding protein specifically expressed in the rat brain". Biochem Biophys Res Commun. 218 (1): 390–4. doi:10.1006/bbrc.1996.0068. PMID   8573167.
6. Raimondi L, D'Asaro M, Proia P, Nastasi T, Di Liegro I (May 2003). "RNA-binding ability of PIPPin requires the entire protein". J Cell Mol Med. 7 (1): 35–42. doi:10.1111/j.1582-4934.2003.tb00200.x. PMC   6740078 . PMID   12767259.
7. "Entrez Gene: CSDC2 cold shock domain containing C2, RNA binding".

External links

• Human CSDC2 genome location and CSDC2 gene details page in the UCSC Genome Browser .

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Nastasi T, Scaturro M, Bellafiore M, et al. (1999). "PIPPin is a brain-specific protein that contains a cold-shock domain and binds specifically to H1 degrees and H3.3 mRNAs". J. Biol. Chem. 274 (34): 24087–93. doi: 10.1074/jbc.274.34.24087 . PMID   10446180.
• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID   10591208.
• Nastasi T, Muzi P, Beccari S, et al. (2001). "Specific neurons of brain cortex and cerebellum are PIPPin positive". NeuroReport. 11 (10): 2233–6. doi:10.1097/00001756-200007140-00034. PMID   10923677. S2CID   28313328.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Schäfer C, Steffen H, Krzykowski KJ, et al. (2003). "CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4): G726–34. doi:10.1152/ajpgi.00111.2003. PMID   12801884.
• Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi: 10.1186/gb-2004-5-10-r84 . PMC   545604 . PMID   15461802.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.