CSDE1

CSDE1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WFQ, 1X65, 2YTV, 2YTX, 2YTY
Identifiers
Aliases	CSDE1 , D1S155E, UNR, cold shock domain containing E1
External IDs	OMIM: 191510; MGI: 92356; HomoloGene: 5179; GeneCards: CSDE1; OMA:CSDE1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p13.2 Start 114,716,913 bp [1] End 114,758,676 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3 F2.2|3 45.25 cM Start 102,927,742 bp [2] End 102,965,502 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon Skeletal muscle tissue of rectus abdominis glutes gastrocnemius muscle epithelium of colon Skeletal muscle tissue of biceps brachii muscle of thigh triceps brachii muscle deltoid muscle vastus lateralis muscle Top expressed in Rostral migratory stream vestibular membrane of cochlear duct lacrimal gland primitive streak abdominal wall triceps brachii muscle spermatid ankle vastus lateralis muscle knee joint More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein binding nucleic acid binding RNA binding Cellular component CRD-mediated mRNA stability complex mitochondrial inner membrane plasma membrane Golgi apparatus cytoplasm cytosol Biological process male gonad development regulation of transcription, DNA-templated nuclear-transcribed mRNA catabolic process, no-go decay Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7812 229663 Ensembl ENSG00000009307 ENSMUSG00000068823 UniProt O75534 Q91W50 RefSeq (mRNA) NM_007158 NM_001007553 NM_001130523 NM_001242891 NM_001242892 NM_001242893 NM_001161854 NM_144901 NM_001310693 RefSeq (protein) NP_001007554 NP_001123995 NP_001229820 NP_001229821 NP_001229822 NP_009089 NP_001155326 NP_001297622 NP_659150 Location (UCSC) Chr 1: 114.72 – 114.76 Mb Chr 3: 102.93 – 102.97 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Cold shock domain-containing protein E1 is a protein that in humans is encoded by the CSDE1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000009307 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000068823 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Jeffers M, Paciucci R, Pellicer A (Oct 1990). "Characterization of unr; a gene closely linked to N-ras". Nucleic Acids Res. 18 (16): 4891–9. PMC   331975 . PMID   2204029.
6. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi: 10.1093/dnares/5.6.355 . PMID   10048485.
7. "Entrez Gene: CSDE1 cold shock domain containing E1, RNA-binding".

External links

• Human CSDE1 genome location and CSDE1 gene details page in the UCSC Genome Browser .

Further reading

• Nicolaiew N, Triqueneaux G, Dautry F (1991). "Organization of the human N-ras locus: characterization of a gene located immediately upstream of N-ras". Oncogene. 6 (5): 721–30. PMID   2052355.
• Boussadia O, Jacquemin-Sablon H, Dautry F (1993). "Exon skipping in the expression of the gene immediately upstream of N-ras (unr/NRU)". Biochim. Biophys. Acta. 1172 (1–2): 64–72. doi:10.1016/0167-4781(93)90270-N. PMID   8439573.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Hunt SL, Hsuan JJ, Totty N, Jackson RJ (1999). "unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA". Genes Dev. 13 (4): 437–48. doi:10.1101/gad.13.4.437. PMC   316477 . PMID   10049359.
• Grosset C, Chen CY, Xu N, et al. (2000). "A mechanism for translationally coupled mRNA turnover: interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex". Cell. 103 (1): 29–40. doi: 10.1016/S0092-8674(00)00102-1 . PMID   11051545. S2CID   18135412.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Mitchell SA, Spriggs KA, Coldwell MJ, et al. (2003). "The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr". Mol. Cell. 11 (3): 757–71. doi: 10.1016/S1097-2765(03)00093-5 . PMID   12667457.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Chang TC, Yamashita A, Chen CY, et al. (2004). "UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant". Genes Dev. 18 (16): 2010–23. doi:10.1101/gad.1219104. PMC   514181 . PMID   15314026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Cornelis S, Tinton SA, Schepens B, et al. (2005). "UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein". Nucleic Acids Res. 33 (10): 3095–108. doi:10.1093/nar/gki611. PMC   1142345 . PMID   15928332.
• Patel GP, Ma S, Bag J (2006). "The autoregulatory translational control element of poly(A)-binding protein mRNA forms a heteromeric ribonucleoprotein complex". Nucleic Acids Res. 33 (22): 7074–89. doi:10.1093/nar/gki1014. PMC   1316114 . PMID   16356927.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.