CSTL1

Last updated
CSTL1
Identifiers
Aliases CSTL1 , CTES1, RCET11, dJ322G13.4, cystatin like 1
External IDs MGI: 2652834 HomoloGene: 16283 GeneCards: CSTL1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_138283

NM_177655
NM_001362207

RefSeq (protein)

NP_612140

NP_808323
NP_001349136

Location (UCSC) Chr 20: 23.44 – 23.44 Mb Chr 2: 148.75 – 148.76 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Cystatin-like 1 is a protein that in humans is encoded by the CSTL1 gene. [5]

Contents

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [5]

Related Research Articles

Cystatin A

Cystatin-A is a protein that in humans is encoded by the CSTA gene.

Cystatin B

Cystatin-B is a protein that in humans is encoded by the CSTB gene.

CST4

Cystatin-S is a protein that in humans is encoded by the CST4 gene.

CST1

Cystatin-SN is a protein that in humans is encoded by the CST1 gene.

CST2

Cystatin-SA is a protein that in humans is encoded by the CST2 gene.

CST6 (gene)

Cystatin-M is a protein that in humans is encoded by the CST6 gene.

CST7 (gene)

Cystatin-F is a protein that in humans is encoded by the CST7 gene.

CST5

Cystatin-D is a protein that in humans is encoded by the CST5 gene.

Cathepsin L2

Cathepsin L2, also known as cathepsin V and encoded by the CTSV gene, is a human gene.

CYP3A43

Cytochrome P450 3A43 is a protein that in humans is encoded by the CYP3A43 gene.

CST8 (gene)

Cystatin-8 is a protein that in humans is encoded by the CST8 gene.

Cathepsin F

Cathepsin F is a protein that in humans is encoded by the CTSF gene.

SPEG

Striated muscle preferentially expressed protein kinase, in the human is encoded by the SPEG gene, a member of the myosin light chain kinase protein family. SPEG is involved in the development of the muscle cell cytoskeleton, and the expression of this gene has important roles in the development of skeletal muscles, and their maintenance and function. Mutations are associated with centronuclear myopathies a group of congenital disorders where the cell nuclei are abnormally centrally placed.

CST9L

Cystatin-9-like is a protein that in humans is encoded by the CST9L gene.

SPRY3

Protein sprouty homolog 3 is a protein that in humans is encoded by the SPRY3 gene.

CSRP2

Cysteine and glycine-rich protein 2 is a protein that in humans is encoded by the CSRP2 gene.

CST11 Protein-coding gene in humans

Cystatin-11 is a protein that in humans is encoded by the CST11 gene.

Fetuin-B

Fetuin-B is a protein that in humans is encoded by the FETUB gene.

CLEC4A

C-type lectin domain family 4 member A is a protein that in humans is encoded by the CLEC4A gene.

CACNG1

Voltage-dependent calcium channel gamma-1 subunit is a protein that in humans is encoded by the CACNG1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000125823 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000055177 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: CSTL1 cystatin-like 1".

Further reading