CUZD1

CUZD1
Identifiers
Aliases	CUZD1 , ERG-1, UO-44, ERG1, ITMAP1, CUB and zona pellucida like domains 1
External IDs	OMIM: 616644 MGI: 1202881 HomoloGene: 7389 GeneCards: CUZD1
Gene location (Human)
Chr.	Chromosome 10 (human)
End	122,846,175 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	130,924,021 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; islet of Langerhans; ; stromal cell of endometrium; ; spleen; ; cerebellar hemisphere; ; lymph node; ; right coronary artery; ; hippocampus proper; ; pituitary gland; ; putamen;
	Top expressed in
	pyloric antrum; ; islet of Langerhans; ; duodenum; ; triceps brachii muscle; ; knee joint; ; skeletal muscle tissue; ; sternocleidomastoid muscle; ; seminiferous tubule; ; soleus muscle; ; myocardium of ventricle;
	More reference expression data
	n/a
Orthologs
	50624
	16433
	ENSG00000138161
	ENSMUSG00000040205
	Q86UP6
	P70412
	NM_022034
	NM_008411
	NP_071317
	NP_032437
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 18, 2022

CUB and zona pellucida-like domain-containing protein 1 is a protein that in humans is encoded by the CUZD1 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000138161 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040205 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Chen D, Xu X, Zhu LJ, Angervo M, Li Q, Bagchi MK, Bagchi IC (Dec 1999). "Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1)". J Biol Chem. 274 (45): 32215–24. doi: 10.1074/jbc.274.45.32215 . PMID 10542259.
↑ "Entrez Gene: CUZD1 CUB and zona pellucida-like domains 1".

External links

Human CUZD1 genome location and CUZD1 gene details page in the UCSC Genome Browser .

Leong CT, Ong CK, Tay SK, Huynh H (2007). "Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro". Oncogene. 26 (6): 870–80. doi: 10.1038/sj.onc.1209836 . PMID 16862170.
Blanchetot C, Chagnon M, Dubé N, et al. (2005). "Substrate-trapping techniques in the identification of cellular PTP targets". Methods. 35 (1): 44–53. doi:10.1016/j.ymeth.2004.07.007. PMID 15588985.
Leong CT, Ng CY, Ong CK, et al. (2004). "Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44". Oncogene. 23 (33): 5707–18. doi: 10.1038/sj.onc.1207754 . PMID 15184879.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi: 10.1038/nature02462 . PMID 15164054.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Cayabyab FS, Tsui FW, Schlichter LC (2003). "Modulation of the ERG K+ current by the tyrosine phosphatase, SHP-1". J. Biol. Chem. 277 (50): 48130–8. doi: 10.1074/jbc.M208448200 . PMID 12361947.
Huynh H, Ng CY, Lim KB, et al. (2001). "Induction of UO-44 gene expression by tamoxifen in the rat uterus and ovary". Endocrinology. 142 (7): 2985–95. doi: 10.1210/endo.142.7.8247 . PMID 11416020.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000138161 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040205 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10542259-5] Chen D, Xu X, Zhu LJ, Angervo M, Li Q, Bagchi MK, Bagchi IC (Dec 1999). "Cloning and uterus/oviduct-specific expression of a novel estrogen-regulated gene (ERG1)". J Biol Chem. 274 (45): 32215–24. doi: 10.1074/jbc.274.45.32215 . PMID 10542259.

[entrez-6] "Entrez Gene: CUZD1 CUB and zona pellucida-like domains 1".

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CUZD1

Contents

Related Research Articles

References

External links

Further reading