Calmodulin-binding transcription activator 1

CAMTA1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CXK
Identifiers
Aliases	CAMTA1 , CANPMR, calmodulin binding transcription activator 1
External IDs	OMIM: 611501; MGI: 2140230; HomoloGene: 18942; GeneCards: CAMTA1; OMA:CAMTA1 - orthologs
Gene location (Mouse) Chr. Chromosome 4 (mouse) [1] Band 4|4 E2 Start 150,917,322 bp [1] End 151,861,876 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in ventromedial nucleus superior colliculus inferior colliculi mammillary body lateral septal nucleus lateral hypothalamus central gray substance of midbrain dorsomedial hypothalamic nucleus paraventricular nucleus of hypothalamus cerebellar cortex BioGPS More reference expression data
Gene ontology Molecular function sequence-specific DNA binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleolus cytoplasm cytosol Biological process regulation of transcription, DNA-templated neuromuscular process controlling balance transcription, DNA-templated positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II positive regulation of protein dephosphorylation positive regulation of calcineurin-NFAT signaling cascade Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23261 100072 Ensembl ENSG00000171735 ENSMUSG00000014592 UniProt Q9Y6Y1 A2A891 RefSeq (mRNA) NM_001195563 NM_001242701 NM_015215 NM_001081557 NM_001166021 NM_001195565 RefSeq (protein) NP_001182492 NP_001229630 NP_056030 NP_001336537 NP_001336538 NP_001336539 NP_001336541 NP_001336542 NP_001336543 NP_001336544 NP_001336545 NP_001336546 NP_001336547 NP_001336548 NP_001336549 NP_001336550 NP_001336551 NP_001336552 NP_001336553 NP_001336554 NP_001336555 NP_001336556 NP_001075026 NP_001182494 Location (UCSC) n/a Chr 4: 150.92 – 151.86 Mb PubMed search [2] [3]
Wikidata
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Calmodulin-binding transcription activator 1 is a protein that in humans is encoded by the CAMTA1 gene. ^{[4] [5]}

References

1. GRCm38: Ensembl release 89: ENSMUSG00000014592 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Bouche N, Scharlat A, Snedden W, Bouchez D, Fromm H (Jun 2002). "A novel family of calmodulin-binding transcription activators in multicellular organisms". Journal of Biological Chemistry . 277 (24): 21851–61. doi: 10.1074/jbc.M200268200 . PMID   11925432. S2CID   9090244.
5. "Entrez Gene: CAMTA1 calmodulin binding transcription activator 1".

Further reading

• Katoh M, Katoh M (2004). "Identification and characterization of FLJ10737 and CAMTA1 genes on the commonly deleted region of neuroblastoma at human chromosome 1p36.31-p36.23". International Journal of Oncology . 23 (4): 1219–24. doi:10.3892/ijo.23.4.1219. PMID   12964007.
• Nakatani K, Nishioka J, Itakura T, et al. (2004). "Cell cycle-dependent transcriptional regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells". Int. J. Oncol. 24 (6): 1407–12. doi:10.3892/ijo.24.6.1407 (inactive 11 July 2025). PMID   15138581.
• Barbashina V, Salazar P, Holland EC, et al. (2005). "Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene". Clinical Cancer Research . 11 (3): 1119–28. doi: 10.1158/1078-0432.1119.11.3 . PMID   15709179.
• Henrich KO, Claas A, Praml C, et al. (2007). "Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma". European Journal of Cancer . 43 (3): 607–16. doi:10.1016/j.ejca.2006.09.023. PMID   17222547.
• Huentelman MJ, Papassotiropoulos A, Craig DW, et al. (2007). "Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance" (PDF). Human Molecular Genetics . 16 (12): 1469–77. doi:10.1093/hmg/ddm097. PMID   17470457.