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The Cambridge Biomedical Campus is the largest centre of medical research and health science in Europe. [1] [2] The site is located at the southern end of Hills Road in Cambridge, England.
Over 20,000 people work at the site, which is home to Cambridge University Hospitals NHS Foundation Trust, Royal Papworth Hospital NHS Foundation Trust, AstraZeneca's headquarters, Abcam, the Wellcome Trust, Cancer Research UK, the University of Cambridge's medical school, and the United Kingdom's governmental Medical Research Council, which has National Institute for Health and Care Research-designated biomedical research centre status. [3] Cambridge Biomedical Campus is an accredited UK academic health and science centre.
The Cambridge Biomedical Campus is home to the following institutions. [4]
Addenbrooke's Hospital is a large teaching hospital, and the central focus of the campus.
The Rosie Hospital is Cambridge's first purpose-built maternity hospital, opened in October 1983. A multimillion-pound extension of the Rosie Hospital was completed in 2012.
The Royal Papworth Hospital moved to new premises on the Cambridge Biomedical Campus in Spring 2019. [5] [6]
AstraZeneca's global research and development facility, The Discovery Centre, is located on the campus [7] and is home to over 2,000 employees working in medicines discovery and development, in both small molecules and biologics. Research activities span all preclinical functional groups, including antibody engineering, medicinal chemistry and high throughput screening.
The University of Cambridge Medical School, established in 1976.
The LMB is a molecular biology research institute funded by the UK Medical Research Council. It was founded in Cambridge in 1947 as the Unit for Research on the Molecular Structure of Biological Systems and moved to a site adjacent to Addenbrooke's Hospital in 1962. A 27,000m2 replacement building close to the previous site was completed in 2012 and opened in May 2013. [8]
The laboratory has won twelve Nobel Prizes including the 1962 prize (Physiology or Medicine) awarded for the discovery of the double-helix structure of DNA. [9]
The Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute or 'SCI' is a virtual organisation composed of the Anne McLaren Laboratory for Stem Cell Biology and Regenerative Medicine and the Wellcome Trust Centre for Stem Cell Research, as well as University-based Principal Investigators working in neighbouring Cambridge institutes whose research is primarily focused on stem cell biology and/or translation. The SCI is principally funded by the Wellcome Trust and the Medical Research Council. The Wellcome Trust also funds the SCI's internationally competitive 4-Year PhD Programme in Stem Cell Biology and Medicine. Stem cell biology and regenerative medicine research is a designated University of Cambridge Strategic Initiative.
The aims of the SCI are:
The SCI was formed in 2012 following an £8m investment by the Wellcome Trust and the Medical Research Council. [10] The SCI will eventually be housed in a purpose-built 8000m2 facility to be constructed on the Cambridge Biomedical Campus site.
The Cancer Research UK Cambridge Institute is one of four core funded Cancer Research UK Institutes [11] and a department of the University of Cambridge. In 2018, the department received an annual budget of £45 million, £27.8 million of which came from Cancer Research UK. The institute offers highly competitive PhD programmes; both studentships and clinical research training fellowships (for aspiring clinical academics), attracting applicants from the UK and around the world. Cancer research is a designated University of Cambridge Strategic Initiative.
Research in the Institute focuses primarily on Tumour Ecology and Evolution, with investigations across four main areas: [12]
The centre was officially opened by Queen Elizabeth II in February 2007. In 2018, Professor Gregory Hannon was announced as the new Director, taking over from Professor Simon Tavaré. [13]
Senior Group Leader at the institute, Professor Richard Gilbertson, is the Director of the Cancer Research UK Cambridge Centre, a network that encourages local collaborations between universities, NHS hospitals, and other research organisations. [14]
The CIMR is a cross-departmental institute in the University of Cambridge, receiving funding from the Wellcome Trust. Research is focused on four main areas: misfolded proteins and disease, intracellular membrane traffic, autoimmune disease and haematopoietic stem cell biology. [15]
The Wolfson Brain Imaging Centre was created in 1995 to develop and apply advanced imaging methods to patients with traumatic brain injury. It is unique in being co-located with the Neurosciences Critical Care Unit of Addenbrooke's Hospital. Since its establishment it has become an internationally leading Positron Emission Tomography and Magnetic Resonance Imaging centre.
The Hutchison/MRC Research Centre is a cancer research centre housing researchers from the University of Cambridge Department of Oncology, the MRC Cancer Cell Unit, and the University of Cambridge "Cambridge Molecular Therapeutics Programme". [16] It was built in 2001 with funding from the Medical Research Council and a donation to the University of Cambridge from Hutchison Whampoa Ltd. The Hutchison/MRC Research Centre is a member institute of the Cambridge Cancer Centre, a virtual organisation of Cambridge researchers whose work has current or potential application to cancer research.
The MRC Mitochondrial Biology Unit is a department of the School of Clinical Medicine of the University of Cambridge, funded by the Medical Research Council. It is focused on research to understand mitochondrial process and their involvement in human diseases. [17] It is co-located with the Cambridge Institute for Medical Research in the Wellcome Trust/MRC Building.
The Institute of Metabolic Science (IMS) is dedicated to research, education, prevention and clinical care in the areas of diabetes, obesity and related metabolic and endocrine diseases. [18] The institute is a joint venture between the University of Cambridge, The Medical Research Council, Cambridge University NHS Hospitals Trust and the Wellcome Trust. [19] It is led by co-directors Professor Sir Stephen O'Rahilly and Professor Nick Wareham. Lead researchers include Krishna Chatterjee, David Dunger, Sadaf Farooqi, Nita Forouhi, Stephen O’Rahilly, Nigel Unwin, Antonio Vidal-Puig, Nick Wareham, and Giles Yeo, among many others. [20]
Adjacent to the Institute of Public Health, Cambridge Centre for Brain Repair is a subsidiary of the University of Cambridge Department of Clinical Neurosciences. It is a research institute aiming to "understand, and eventually to alleviate and repair damage to the brain and spinal cord which results from injury or neurodegenerative disease." [21]
The Institute for Public Health is a partnership between the University of Cambridge, the Medical Research Council and the National Health Service. It was created in 1993 to study disease in the population and to identify, evaluate and monitor public healthcare interventions. [22]
The Cambridge Academy for Science and Technology is a secondary school for 14- to 18-year-olds offering GCSE, B-Tech and A-Level courses. It opened on 8 September 2014 in the Deakin Centre as the University Technical College Cambridge. On Friday 19 September 2017, it moved into its own building on Robinson Way, situated next to the Long Road Sixth Form College, parallel to the Bio-Medical Campus which encompasses Addenbrooke's Hospital, rebranded as Cambridge Academy for Science and Technology.
Other entities located on the Cambridge Biomedical Campus include:
Within the next decade, there are scheduled to be 3 new hospitals (including one rebuild) on the Biomedical Campus, bringing the total number of hospitals on the Campus to 5: [23]
A new railway station, Cambridge South railway station, is due to be built adjacent to the Campus, as part of the construction of the East West Rail project between the university towns of Cambridge and Oxford. [24] [25]
Addenbrooke's Hospital is a large teaching hospital and research centre in Cambridge, England, with strong affiliations to the University of Cambridge. Addenbrooke's Hospital is located on the Cambridge Biomedical Campus. It is run by Cambridge University Hospitals NHS Foundation Trust and is a designated academic health science centre. It is also the East of England's major trauma centre and was the first such centre to be operational in the United Kingdom.
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy.
Cambridge University Hospitals NHS Foundation Trust is a British public sector healthcare provider located in Cambridge, England. It was established on 4 November 1992 as Addenbrooke's National Health Service Trust, and authorised as an NHS foundation trust under its current name on 1 July 2004.
The School of Clinical Medicine is the medical school of the University of Cambridge in England. The medical school is considered as being one of the most prestigious in the world, ranking as 1st in The Complete University Guide, followed by Oxford University Medical School, Harvard Medical School, and Stanford School of Medicine and 2nd in the world in the 2023 Times Higher Education Ranking. The Cambridge Graduate Course in Medicine (A101) is the most competitive course offered by the University and in the UK, and is among the most competitive medical programs for entry in the world. The school is located alongside Addenbrooke's Hospital and other institutions in multiple buildings across the Cambridge Biomedical Campus.
Sir David Keith Peters is a retired Welsh physician and academic. He was Regius Professor of Physic at the University of Cambridge from 1987 to 2005, where he was also head of the School of Clinical Medicine.
The MRC Mitochondrial Biology Unit is a department of the School of Clinical Medicine at the University of Cambridge, funded through a strategic partnership between the Medical Research Council and the University. It is located at the Addenbrooke’s Hospital / Cambridge Biomedical Campus site in Cambridge, England. The unit is concerned with the study of the mitochondrion, as this organelle has a varied and critical role in many aspects of eukaryotic metabolism and is implicated in many metabolic, degenerative, and age-related human diseases.
Sir Menelaos (Mene) Nicolas Pangalos is a British neuroscientist of Greek descent.
Fiona Watt, is a British scientist who is internationally known for her contributions to the field of stem cell biology. In the 1980s, when the field was in its infancy, she highlighted key characteristics of stem cells and their environment that laid the foundation for much present day research. She is currently Director of the European Molecular Biology Organization (EMBO). after previously serving as director of the Centre for Stem Cells & Regenerative Medicine at King's College London, and Executive Chair of the Medical Research Council (MRC), the first woman to lead the MRC since its foundation in 1913.
The Wellcome – MRC Cambridge Stem Cell Institute at the University of Cambridge is a research centre for the nature and potential medical uses of stem cells. It is located on the Cambridge Biomedical Campus in Cambridge, England.
The School of Biological Sciences is a research-led academic community at the University of East Anglia. It works with partners in industry on a range of activities, including translating research discoveries into products, making knowledge and research expertise available through consultancies, contract research and provision of analytical services, as well as partnering industry in training both undergraduate and postgraduate students.
The UCL Institute of Ophthalmology is an institute within the Faculty of Brain Sciences of University College London (UCL) and is based in London, United Kingdom. The institute conducts research and post-graduate teaching in the area of ophthalmology.
Sir Stephen Patrick O'Rahilly is an Irish-British physician and scientist known for his research into the molecular pathogenesis of human obesity, insulin resistance and related metabolic and endocrine disorders.
Sir John Gerald Patrick Sissons was an English physician, specialising in nephrology and virology, focusing on cytomegalovirus. He was aFRCP, FRCPath, FMedSci and Regius Professor of Physic at the University of Cambridge.
Giovanna Rachele Mallucci is van Geest Professor of Clinical Neurosciences at the University of Cambridge in England and associate director of the UK Dementia Research Institute at the University of Cambridge. She is a specialist in neurodegenerative diseases.
Sussan Nourshargh is a British immunologist, pharmacologist, and professor of microvascular pharmacology and immunopharmacology. She founded the Centre for Microvascular research at Queen Mary University.
Antonio Vidal-Puig is a Spanish medical doctor and scientist who works as a Professor of Molecular Nutrition and Metabolism at the University of Cambridge (UK), best known for advancing the concept that pharmacological targeting of brown fat may serve to treat overweight and obesity in affected individuals, as well as for introducing the concept of adipose tissue "expandability" as an important factor in the pathogenesis of insulin resistance in the context of positive energy balance. His published work focuses on areas such as adipose tissue metabolism and lipotoxicity, regulation of insulin secretion, and the pathophysiology of metabolic syndrome, obesity, and type 2 diabetes.
The MRC Weatherall Institute of Molecular Medicine at the University of Oxford is a research institute located at the John Radcliffe Hospital in Oxford. Founded in 1989 by Sir David Weatherall, the institute focuses on furthering our understanding of clinical medicine at a molecular level. It was one of the first institutes of its kind in the world to be dedicated to research in this area.
Professor Patrick Francis Chinnery, FRCP, FRCPath, FMedSci, is a neurologist, clinician scientist, and Wellcome Trust Principal Research Fellow based in the Medical Research Council Mitochondrial Biology Unit and the University of Cambridge, where he is also Professor of Neurology and Head of the Department of Clinical Neurosciences.
The Cambridge Institute for Medical Research (CIMR) is an interdisciplinary research institute within the University of Cambridge School of Clinical Medicine. CIMR is on the Cambridge Biomedical Campus, in the Keith Peters Building, a dedicated research building that it shares with the Medical Research Council Mitochondrial Biology Unit.