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In vertebrates, a neuroblast or primitive nerve cell is a postmitotic cell that does not divide further, and which will develop into a neuron after a migration phase. In invertebrates such as Drosophila, neuroblasts are neural progenitor cells which divide asymmetrically to produce a neuroblast, and a daughter cell of varying potency depending on the type of neuroblast. Vertebrate neuroblasts differentiate from radial glial cells and are committed to becoming neurons. Neural stem cells, which only divide symmetrically to produce more neural stem cells, transition gradually into radial glial cells. Radial glial cells, also called radial glial progenitor cells, divide asymmetrically to produce a neuroblast and another radial glial cell that will re-enter the cell cycle.
Nicole King is an American biologist and faculty member at the University of California, Berkeley in molecular and cell biology and integrative biology. She was awarded a MacArthur Fellowship in 2005. She has been an investigator with the Howard Hughes Medical Institute (HHMI) since 2013.
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Judith S. Eisen is an American neuroscientist and professor of biology at the University of Oregon. Eisen conducts fundamental research in the specification and patterning of the vertebrate nervous system with a focus on developmental interactions between the nervous system, immune system, and host-associated microbiota. Eisen is a member of the Institute of Neuroscience at the University of Oregon.
References
- ↑ "Chris Doe | Institute of Neuroscience". ion.uoregon.edu.
- ↑ "Chris Q. Doe, PhD | HHMI.org". HHMI.org.
- ↑ "cq doe - Google Scholar Citations". scholar.google.co.uk.
- ↑ Doe, CQ; Goodman, CS (September 1985). "Early events in insect neurogenesis. II. The role of cell interactions and cell lineage in the determination of neuronal precursor cells". Developmental Biology. 111 (1): 206–19. doi:10.1016/0012-1606(85)90446-4. PMID 4029507.
- ↑ "Home". www.doelab.org.
- ↑ "National Academy of Sciences members 2017".