Chromatin accessibility complex 1

CHRAC1
Identifiers
Aliases	CHRAC1 , CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1, chromatin accessibility complex 1, chromatin accessibility complex subunit 1
External IDs	OMIM: 607268 MGI: 2135796 HomoloGene: 41174 GeneCards: CHRAC1
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8q24.3 Start 140,511,311 bp [1] End 140,517,154 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 D3 Start 72,962,241 bp [2] End 72,969,403 bp [2]
RNA expression pattern Bgee Top expressed in thymus gastrocnemius muscle muscle of leg thoracic aorta pancreas thyroid gland More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity DNA binding DNA-directed DNA polymerase activity nucleotidyltransferase activity GO:0001948 protein binding protein heterodimerization activity Cellular component epsilon DNA polymerase complex nucleus CHRAC Biological process DNA biosynthetic process chromatin remodeling nucleosome mobilization Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54108	93696
Ensembl	ENSG00000104472	ENSMUSG00000068391
UniProt	Q9NRG0	Q9JKP8
RefSeq (mRNA)	NM_017444	NM_053068
RefSeq (protein)	NP_059140	NP_444298
Location (UCSC)	Chr 8: 140.51 – 140.52 Mb	Chr 15: 72.96 – 72.97 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Chromatin accessibility complex 1 is a protein that in humans is encoded by the CHRAC1 gene. ^[5]

Function

CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

References

1. GRCh38: Ensembl release 89: ENSG00000104472 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000068391 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Chromatin accessibility complex 1" . Retrieved 2016-10-26.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.