DCAF8

DCAF8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3I8E
Identifiers
Aliases	DCAF8 , GAN2, H326, WDR42A, DDB1 and CUL4 associated factor 8
External IDs	OMIM: 615820 MGI: 91860 HomoloGene: 56725 GeneCards: DCAF8
Gene location (Human)
Chr.	Chromosome 1 (human)
End	160,262,549 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	172,197,005 bp
Gene ontology
Molecular function	• GO:0001948 protein binding ;
Cellular component	• nucleoplasm ; • mitochondrion ; • cytosol ; • cytoplasm ; • Cul4-RING E3 ubiquitin ligase complex ; • nucleus ;
Biological process	• post-translational protein modification ; • protein ubiquitination ;
	Sources:Amigo / QuickGO
Orthologs
	50717
	98193
	ENSG00000132716
	ENSMUSG00000026554
	Q5TAQ8 ; Q5TAQ9
	Q8N7N5
	NM_015726
	NM_153555 ; NM_001357204
	NP_056541
	NP_705783 ; NP_001344133
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 11, 2021

DDB1 and CUL4 associated factor 8 is a protein that in humans is encoded by the DCAF8 gene. ^[5]

Function

This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009].

Related Research Articles

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DDB1 and CUL4 associated factor 17 is a protein that in humans is encoded buy the DCAF17 gene.

Coronin, actin binding protein, 2A is a protein that in humans is encoded by the CORO2A gene.

Tetratricopeptide repeat domain 28 is a protein that in humans is encoded by the TTC28 gene.

WD repeat containing planar cell polarity effector is a protein that in humans is encoded by the WDPCP gene.

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Mediator complex subunit 19 (Med19) is a protein that in humans is encoded by the MED19 gene.

V-set and immunoglobulin domain containing 1 is a protein that in humans is encoded by the VSIG1 gene.

DDB1 and CUL4 associated factor 15 is a protein that in humans is encoded by the DCAF15 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000132716 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026554 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: DDB1 and CUL4 associated factor 8" . Retrieved 2018-08-23.

DCAF8

Contents

Function

Related Research Articles

References

Further reading