DCBLD2

DCBLD2
Identifiers
Aliases	DCBLD2 , CLCP1, ESDN, discoidin, CUB and LCCL domain containing 2
External IDs	OMIM: 608698 MGI: 1920629 HomoloGene: 12499 GeneCards: DCBLD2
Gene location (Human)
Chr.	Chromosome 3 (human)
End	98,901,695 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	58,469,727 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; vena cava; ; parotid gland; ; body of tongue; ; synovial joint; ; cardia; ; pons; ; pylorus; ; saphenous vein; ; pericardium;
	Top expressed in
	atrium; ; pineal gland; ; secondary oocyte; ; epithelium of stomach; ; belly cord; ; external carotid artery; ; trigeminal ganglion; ; internal carotid artery; ; cumulus cell; ; calvaria;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	integral component of membrane ; cell surface ; integral component of plasma membrane ; membrane ;
Biological process	intracellular receptor signaling pathway ; wound healing ; negative regulation of cell growth ;
	Sources:Amigo / QuickGO
Orthologs
	131566
	73379
	ENSG00000057019
	ENSMUSG00000035107
	Q96PD2
	Q91ZV3
	NM_080927
	NM_028523 ; NM_001356484
	NP_563615
	NP_082799 ; NP_001343413
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 18, 2024

Discoidin, CUB and LCCL domain-containing protein 2 is a protein that in humans is encoded by the DCBLD2 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000057019 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035107 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Kobuke K, Furukawa Y, Sugai M, Tanigaki K, Ohashi N, Matsumori A, Sasayama S, Honjo T, Tashiro K (Sep 2001). "ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury". The Journal of Biological Chemistry. 276 (36): 34105–14. doi: 10.1074/jbc.M105293200 . hdl: 2433/150206 . PMID 11447234.
↑ "Entrez Gene: DCBLD2 discoidin, CUB and LCCL domain containing 2".

Sadeghi MM, Esmailzadeh L, Zhang J, Guo X, Asadi A, Krassilnikova S, Fassaei HR, Luo G, Al-Lamki RS, Takahashi T, Tellides G, Bender JR, Rodriguez ER (Sep 2007). "ESDN is a marker of vascular remodeling and regulator of cell proliferation in graft arteriosclerosis". American Journal of Transplantation. 7 (9): 2098–105. doi:10.1111/j.1600-6143.2007.01919.x. PMID 17697260. S2CID 28463596.
Chen Y, Low TY, Choong LY, Ray RS, Tan YL, Toy W, Lin Q, Ang BK, Wong CH, Lim S, Li B, Hew CL, Sze NS, Druker BJ, Lim YP (Jul 2007). "Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells". Proteomics. 7 (14): 2384–97. doi:10.1002/pmic.200600968. PMID 17570516. S2CID 23944956.
Zhang Y, Wolf-Yadlin A, Ross PL, Pappin DJ, Rush J, Lauffenburger DA, White FM (Sep 2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Molecular & Cellular Proteomics. 4 (9): 1240–50. doi: 10.1074/mcp.M500089-MCP200 . PMID 15951569.
Koshikawa K, Osada H, Kozaki K, Konishi H, Masuda A, Tatematsu Y, Mitsudomi T, Nakao A, Takahashi T (Apr 2002). "Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo". Oncogene. 21 (18): 2822–8. doi:10.1038/sj.onc.1205405. PMID 11973641. S2CID 1747522.
Nadadur SS, Ehrke MJ, Gurtoo HL (Dec 1999). "A novel TNF-inducible message with putative growth suppressor function". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1489 (2–3): 433–9. doi:10.1016/s0167-4781(99)00189-x. PMID 10673047.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000057019 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035107 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11447234-5] Kobuke K, Furukawa Y, Sugai M, Tanigaki K, Ohashi N, Matsumori A, Sasayama S, Honjo T, Tashiro K (Sep 2001). "ESDN, a novel neuropilin-like membrane protein cloned from vascular cells with the longest secretory signal sequence among eukaryotes, is up-regulated after vascular injury". The Journal of Biological Chemistry. 276 (36): 34105–14. doi: 10.1074/jbc.M105293200 . hdl: 2433/150206 . PMID 11447234.

[entrez-6] "Entrez Gene: DCBLD2 discoidin, CUB and LCCL domain containing 2".

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DCBLD2

Related Research Articles

References

Further reading