DCHS2

Last updated
DCHS2
Identifiers
Aliases DCHS2 , CDH27, CDHJ, CDHR7, PCDH23, PCDHJ, dachsous cadherin-related 2
External IDs OMIM: 612486 HomoloGene: 130686 GeneCards: DCHS2
Gene location (Human)
Ideogram human chromosome 4.svg
Chr. Chromosome 4 (human) [1]
Human chromosome 4 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 4q31.3Start154,231,742 bp [1]
End154,491,799 bp [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001142552
NM_001142553
NM_017639
NM_199348
NM_001358235

n/a

RefSeq (protein)

NP_001136024
NP_001345164

n/a

Location (UCSC) Chr 4: 154.23 – 154.49 Mb n/a
PubMed search [2] n/a
Wikidata
View/Edit Human

Protein dachsous homolog 2, also known as protocadherin-23 (PCDH23) or cadherin-27 (CDH27), is a protein that in humans is encoded by the DCHS2 gene. [3] [4]

DCHS2 has been implicated in the nose angle (how much a nose is upturned). [5] As well as facial genetics [6] [7]

Related Research Articles

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DNAJC28

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References

  1. 1 2 3 ENSG00000284227 GRCh38: Ensembl release 89: ENSG00000197410, ENSG00000284227 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: dachsous 2 (Drosophila)".
  4. Höng JC, Ivanov NV, Hodor P, Xia M, Wei N, Blevins R, Gerhold D, Borodovsky M, Liu Y (March 2004). "Identification of new human cadherin genes using a combination of protein motif search and gene finding methods". J. Mol. Biol. 337 (2): 307–17. doi:10.1016/j.jmb.2004.01.026. PMID   15003449.
  5. "A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation".
  6. "Facial Genetics: a Brief Overview" (PDF).
  7. "Your nose--Big or small--is shaped by your DNA".

Further reading