DCUN1D4

DCUN1D4
Identifiers
Aliases	DCUN1D4 , defective in cullin neddylation 1 domain containing 4, DCNL4
External IDs	OMIM: 612977 MGI: 2140972 HomoloGene: 22867 GeneCards: DCUN1D4
Gene location (Human)
Chr.	Chromosome 4 (human)
End	51,916,837 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	73,718,137 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; germinal epithelium; ; popliteal artery; ; gastric mucosa; ; Stromal cell of endometrium; ; urinary bladder; ; right coronary artery; ; anterior pituitary; ; tibial nerve; ; right uterine tube;
	Top expressed in
	spermatid; ; visual cortex; ; lateral hypothalamus; ; amygdala; ; superior frontal gyrus; ; ventromedial nucleus; ; yolk sac; ; paraventricular nucleus of hypothalamus; ; medial vestibular nucleus; ; hand;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	cullin family protein binding ; ubiquitin-like protein binding ; protein binding ; ubiquitin conjugating enzyme binding ; molecular function ;
Cellular component	nucleus ; ubiquitin ligase complex ;
Biological process	protein neddylation ; positive regulation of ubiquitin-protein transferase activity ; biological process ;
	Sources:Amigo / QuickGO
Orthologs
	23142
	100737
	ENSG00000109184
	ENSMUSG00000051674
	Q92564
	Q8CCA0
	NM_001040402 ; NM_001287755 ; NM_001287757 ; NM_015115
	NM_001190733 ; NM_001190734 ; NM_178896
	NP_001035492 ; NP_001274684 ; NP_001274686 ; NP_055930
	NP_001177662 ; NP_001177663 ; NP_849227
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 15, 2022

DCN1-like protein 4 is a protein that in humans is encoded by the DCUN1D4 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000109184 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051674 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M (Jun 2005). "The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae". Nature. 435 (7046): 1257–61. doi:10.1038/nature03662. PMID 15988528. S2CID 4328225.
↑ "Entrez Gene: DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)".

Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi: 10.1093/dnares/3.5.321 . PMID 9039502.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000109184 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051674 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15988528-5] Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M (Jun 2005). "The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae". Nature. 435 (7046): 1257–61. doi:10.1038/nature03662. PMID 15988528. S2CID 4328225.

[entrez-6] "Entrez Gene: DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)".

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DCUN1D4

Related Research Articles

References

Further reading