DCUN1D4

DCUN1D4
Identifiers
Aliases	DCUN1D4 , defective in cullin neddylation 1 domain containing 4, DCNL4
External IDs	OMIM: 612977; MGI: 2140972; HomoloGene: 22867; GeneCards: DCUN1D4; OMA:DCUN1D4 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) [1] Band 4q12 Start 51,843,000 bp [1] End 51,916,837 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5|5 C3.3 Start 73,638,343 bp [2] End 73,718,137 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon epithelium of colon germinal epithelium testicle left ovary right ovary tail of epididymis popliteal artery gastric mucosa tibial arteries Top expressed in spermatid visual cortex lateral hypothalamus amygdala primary visual cortex superior frontal gyrus ventromedial nucleus zygote genital tubercle yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function cullin family protein binding ubiquitin-like protein binding protein binding ubiquitin conjugating enzyme binding molecular function Cellular component nucleus ubiquitin ligase complex Biological process protein neddylation positive regulation of ubiquitin-protein transferase activity biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23142 100737 Ensembl ENSG00000109184 ENSMUSG00000051674 UniProt Q92564 Q8CCA0 RefSeq (mRNA) NM_001040402 NM_001287755 NM_001287757 NM_015115 NM_001190733 NM_001190734 NM_178896 RefSeq (protein) NP_001035492 NP_001274684 NP_001274686 NP_055930 NP_001177662 NP_001177663 NP_849227 Location (UCSC) Chr 4: 51.84 – 51.92 Mb Chr 5: 73.64 – 73.72 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

DCN1-like protein 4 is a protein that in humans is encoded by the DCUN1D4 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000109184 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051674 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M (Jun 2005). "The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae". Nature. 435 (7046): 1257–61. Bibcode:2005Natur.435.1257K. doi:10.1038/nature03662. PMID   15988528. S2CID   4328225.
6. "Entrez Gene: DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)".

Further reading

• Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi: 10.1093/dnares/3.5.321 . PMID   9039502.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.