DIPK1C

DIPK1C
Identifiers
Aliases	DIPK1C , C18orf51, family with sequence similarity 69 member C, divergent protein kinase domain 1C, FAM69C, FNCAD
External IDs	OMIM: 614544; MGI: 3041188; HomoloGene: 45477; GeneCards: DIPK1C; OMA:DIPK1C - orthologs
Gene location (Human) Chr. Chromosome 18 (human) [1] Band 18q22.3 Start 74,434,775 bp [1] End 74,457,944 bp [1]
Gene location (Mouse) Chr. Chromosome 18 (mouse) [2] Band 18|18 E4 Start 84,737,361 bp [2] End 84,758,561 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone putamen endothelial cell caudate nucleus internal globus pallidus amygdala apex of heart ganglionic eminence substantia nigra nucleus accumbens Top expressed in ventricular zone lower lip upper lip vestibular labyrinth retina layer of retina neural layer of retina mesencephalon embryo rhombencephalon More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 125704 240479 Ensembl ENSG00000187773 ENSMUSG00000047992 UniProt Q0P6D2 Q8BQT2 RefSeq (mRNA) NM_001044369 NM_173770 RefSeq (protein) NP_001037834 NP_776131 Location (UCSC) Chr 18: 74.43 – 74.46 Mb Chr 18: 84.74 – 84.76 Mb PubMed search [3] [4]
Wikidata
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Divergent protein kinase domain 1C is a protein that in humans is encoded by the DIPK1C gene. ^[5]

Function

This gene encodes a member of the divergent protein kinase domain family (DIPK) ^[6] of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown.

References

1. GRCh38: Ensembl release 89: ENSG00000187773 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047992 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Family with sequence similarity 69, member C".
6. "Gene group: divergent protein kinase domain family (DIPK)". Human Genome Organisation.

Further reading

• Tennant-Eyles AJ, Moffitt H, Whitehouse CA, Roberts RG (March 2011). "Characterisation of the FAM69 family of cysteine-rich endoplasmic reticulum proteins". Biochemical and Biophysical Research Communications. 406 (3): 471–7. doi:10.1016/j.bbrc.2011.02.076. PMID   21334309.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.