DIRC2

SLC49A4
Identifiers
Aliases	SLC49A4 , RCC4, disrupted in renal carcinoma 2, solute carrier family 49 member 4, DIRC2
External IDs	OMIM: 602773 MGI: 2387188 HomoloGene: 13137 GeneCards: SLC49A4
Gene location (Human)
Chr.	Chromosome 3 (human)
End	122,881,139 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	35,589,726 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; placenta; ; tibialis anterior muscle; ; deltoid muscle; ; pancreatic epithelial cell; ; palpebral conjunctiva; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; biceps brachii; ; cavity of mouth;
	Top expressed in
	sternocleidomastoid muscle; ; triceps brachii muscle; ; gastrocnemius muscle; ; interventricular septum; ; quadriceps femoris muscle; ; temporal muscle; ; knee joint; ; vastus lateralis muscle; ; skeletal muscle tissue; ; digastric muscle;
	More reference expression data
	n/a
Orthologs
	84925
	224132
	ENSG00000138463
	ENSMUSG00000022848
	Q96SL1
	Q8BFQ6
	NM_032839
	NM_153550
	NP_116228
	NP_705778
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Disrupted in renal carcinoma 2 is a protein that in humans is encoded by the DIRC2 gene.^[5]

Function

This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas.^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000138463 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022848 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 "Entrez Gene: Disrupted in renal carcinoma 2".

DIRC2

Contents

Function

Related Research Articles

References

Further reading