8-Oxoguanine glycosylase, also known as OGG1, is a DNA glycosylase enzyme that, in humans, is encoded by the OGG1 gene. It is involved in base excision repair. It is found in bacterial, archaeal and eukaryotic species.
25-Hydroxyvitamin D 1-alpha-hydroxylase also known as calcidiol 1-monooxygenase or cytochrome p450 27B1 (CYP27B1) or simply 1-alpha-hydroxylase is a cytochrome P450 enzyme that in humans is encoded by the CYP27B1 gene.
The neuropeptide S receptor (NPSR) is a member of the G-protein coupled receptor superfamily of integral membrane proteins which binds neuropeptide S (NPS). It was formerly an orphan receptor, GPR154, until the discovery of neuropeptide S as the endogenous ligand. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Mutations in this gene have also been associated with this disease.
Calpain-10 is a protein that in humans is encoded by the CAPN10 gene.
NK2 homeobox 1 (NKX2-1), also known as thyroid transcription factor 1 (TTF-1), is a protein which in humans is encoded by the NKX2-1 gene.
Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene.
Glutathione S-transferase M3 (brain), also known as GSTM2, is an enzyme which in humans is encoded by the GSTM99 gene.
Glutathione S-transferase theta-2 is an enzyme that in humans is encoded by the GSTT2 gene.
L-myc-1 proto-oncogene protein is a protein that in humans is encoded by the MYCL1 gene.
Semaphorin-3B is a protein that in humans is encoded by the SEMA3B gene.
Cytochrome P450 2A13 is a protein that in humans is encoded by the CYP2A13 gene.
Zinc transporter 1 is a protein which in humans is encoded by the SLC30A1 gene.
CYP2A7 is a protein that in humans is encoded by the CYP2A7 gene.
Cleft lip and palate transmembrane protein 1-like protein, also known as cisplatin resistance-related protein 9 (CRR9p), is a protein that in humans is encoded by the CLPTM1L gene. CRR9p is associated with cisplatin-induced apoptosis. CLPTM1L, which lies within a cancer susceptibility locus on chromosome 5 (5p15.33), has been found to be commonly over-expressed in lung tumors and to confer resistance to apoptosis caused by genotoxic agents in association with up-regulation of the anti-apoptotic protein, Bcl-xL. Inhibition of CLPTM1L has been shown to inhibit oncogenic transformation and tumorigenesis caused by the KRas oncogene partially through the PI3K/Akt survival signaling axis.
Glutathione peroxidase 3 (GPx-3), also known as plasma glutathione peroxidase (GPx-P) or extracellular glutathione peroxidase is an enzyme that in humans is encoded by the GPX3 gene.
N-acetyltransferase 1 is a protein that in humans is encoded by the NAT1 gene.
HHIP-like protein 1 (HHIPL1), also known as HHIP2, is a protein that in humans is encoded by the HHIPL1 gene on chromosome 14. It is not significantly expressed in many tissues and cell types, though HHIPL1 mRNA has been detected in trabecular bone cells. Little is known about the precise biological function of HHIPL1, but the protein has been linked to adenomas. The HHIPL1 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.
GEN1, Holliday junction 5' flap endonuclease is a protein that in humans is encoded by the GEN1 gene.
IGF2 antisense RNA is a protein that in humans is encoded by the IGF2-AS gene.
Leiomodin 1 is a protein that in humans is encoded by the LMOD1 gene.
