Daniel John DiLorenzo is a medical device entrepreneur and physician-scientist. He is the inventor of several technologies for the treatment of neurological disease and is the founder of several companies which are developing technologies to treat epilepsy and other medical diseases and improve the quality of life of afflicted patients. [1]
DiLorenzo studied at MIT, receiving a B.S. and M.S. in electrical engineering, M.S. in health sciences and technology, an M.B.A./M.S. in the Management of Technology from the MIT Sloan School of Management, and a Ph.D. in mechanical engineering, with a focus on neurophysiology, control theory, and implantable neural interfaces. He also received the M.D. degree from Harvard Medical School. [2]
As a 1st grader, DiLorenzo decided to forego the opportunity to attend summer camp. Instead, he spent his summer building a robot with telescoping arms that had the ability to shoot rockets. [2] DiLorenzo functions on zero to four hours of sleep and routinely is awake between the hours of one to three AM. [2]
DiLorenzo developed closed-loop neuromodulation technology on his own while a student at MIT and developed several technologies for the treatment of neurological disease, including a gait restoration system for paraplegics, a peripheral nerve interface for amputees, among others.
DiLorenzo is the inventor of novel devices and methods for the treatment of patients with epilepsy. Based upon his inventions, he founded NeuroVista Corporation while a Neurosurgery resident in 2002 (formerly known as BioNeuronics, Seattle, WA) and which has developed and successfully demonstrated a novel brain monitoring technology that is capable of predicting seizures in patients with epilepsy.
While at BioNeuronics, an early-stage medical device company developing devices for epilepsy, he also founded DiLorenzo Biomedical, a medical device company developing novel therapies for obesity and other medical conditions.
He is the editor of the Textbook "Neuroengineering", which provides an overview of the new technologies, surgical techniques, and clinical indications of neuroengineering. [1] [3]
DiLorenzo is the recipient of several awards related to invention and innovation. He won the MIT-Lemelson $30,000 Student Prize, was included in the TR100 list of 100 young innovators, was featured in Entrepreneur Magazine as an innovator in business, and was included in the Seattle 40 under 40 Leaders in Business. [1]
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system.
Robert Samuel Langer Jr. FREng is an American biotechnologist, businessman, chemical engineer, chemist, and inventor. He is one of the nine Institute Professors at the Massachusetts Institute of Technology.
Vagus nerve stimulation (VNS) is a medical treatment that involves delivering electrical impulses to the vagus nerve. It is used as an add-on treatment for certain types of intractable epilepsy, cluster headaches, treatment-resistant depression and stroke rehabilitation.
Neural engineering is a discipline within biomedical engineering that uses engineering techniques to understand, repair, replace, or enhance neural systems. Neural engineers are uniquely qualified to solve design problems at the interface of living neural tissue and non-living constructs.
Angela M. Belcher is a materials scientist, biological engineer, and the James Mason Crafts Professor of Biological Engineering and Materials Science at the Massachusetts Institute of Technology (MIT) in Cambridge, Massachusetts, United States. She is director of the Biomolecular Materials Group at MIT, a member of the Koch Institute for Integrative Cancer Research, and a 2004 MacArthur Fellow. In 2019, she was named head of the Department of Biological Engineering at MIT. She was elected a member of the National Academy of Sciences in 2022.
Georgetown University Medical Center is a Washington, D.C.-based biomedical research and educational organization affiliated with Georgetown University that is responsible for over 80% of the university's sponsored research funding and is led by Edward B. Healton, MD, the Executive Vice President for Health Sciences and Executive Dean of the School of Medicine.
The Lemelson Foundation is an American 501(c)(3) private foundation. It was started in 1993 by Jerome H. Lemelson and his wife Dorothy. The foundation held total net assets of US$444,124,049 at the end of 2020 and US$484,432,021 at the end of 2021. The Foundation seeks to harness the power of invention and innovation to accelerate climate action and improve lives around the world.
Dr. Thomas J. "Tom" Fogarty is an American surgeon and medical device inventor. He is best known for the invention of the embolectomy catheter, which revolutionized the treatment of blood clots (embolus).
Bin He is a Chinese American biomedical engineering scientist. He is the Trustee Professor of the Department of Biomedical Engineering, professor by courtesy in the Department of Electrical and Computer Engineering, and Professor of Neuroscience Institute, and was the head of the department of Biomedical Engineering at Carnegie Mellon University. Prior, he was Distinguished McKnight University Professor of Biomedical Engineering and Medtronic-Bakken Endowed Chair for Engineering in Medicine at the University of Minnesota. He previously served as the director of the Institute for Engineering in Medicine and the Center for Neuroengineering at the University of Minnesota. He was the Editor in Chief of the IEEE Transactions on Biomedical Engineering and serves as the editor in chief of IEEE Reviews in Biomedical Engineering. He was the president of the IEEE Engineering in Medicine & Biology Society (EMBS) from 2009 to 2010 and chair of International Academy of Medical and Biological Engineering from 2018 to 2021.
Corinna E. Lathan is an American entrepreneur, engineer, and social activist. She is the author of InventingThe Future: Stories from a Techno Optimist. Dr. Lathan is currently CEO of De Oro Devices. She is also the Co-Founder, and former CEO and Board Chair of AnthroTronix, Inc., a biomedical research and development company headquartered in Silver Spring, Maryland, USA. Lathan is recognized for her work on digital health software and assistive technology.
Andrew Heafitz is an American inventor. He is the VP of product development at Terrafugia, a company developing a flying car.
Geoffrey Louis Barrows is an American inventor and the founder of Centeye, a company that specializes in the development of insect vision for robotics. In 2003 he was recognized as a Young Innovator by being included in the MIT Technology Review's TR100 list. Barrows owns more than six patents for his technology.
Shuvo Roy is an American scientist and engineer of South Asian descent.
Ramesh Raskar is a Massachusetts Institute of Technology associate professor and head of the MIT Media Lab's Camera Culture research group. Previously he worked as a senior research scientist at Mitsubishi Electric Research Laboratories (MERL) during 2002 to 2008. He holds 132 patents in computer vision, computational health, sensors and imaging. He received the $500K Lemelson–MIT Prize in 2016. The prize money will be used for launching REDX.io, a group platform for co-innovation in Artificial Intelligence. He is well known for inventing EyeNetra, EyeCatra and EyeSelfie, Femto-photography and his TED talk for cameras to see around corners.
Isabelle M. Germano is a neurosurgeon and professor of neurosurgery, neurology, and oncology at the Icahn School of Medicine at Mount Sinai Hospital. She is a Fellow of the American College of Surgeons and the American Association of Neurological Surgeons. Germano works with image-guided brain and spine surgery.
Jacob Chandy was an Indian neurosurgeon and teacher of medical sciences. As the first neurosurgeon in India, he is widely regarded as the father of modern neurosurgery in India. In 1964, the Government of India honoured him with their third highest civilian award, Padmabhushan, for his services in the fields of neurosurgery and medical education.
Ana Maiques is a Spanish entrepreneur and business executive. She is the CEO and co-founder of Neuroelectrics, a company based in Barcelona that develops non-invasive brain stimulation devices to treat neurological disorders. Maiques is also the President of EsTech, a platform for high-growth technology companies in Spain, and a member of the European Innovation Council Advisory Board. She is a prominent advocate for gender diversity in STEM fields, promoting women's representation in tech and business. Ana Maiques was named as one of the Most Inspiring Fifty Women in Europe.
Subramanian Kalyanaraman is an Indian neurosurgeon and a former head of the Department of Neurosurgery at Apollo Hospitals, Chennai. He was known for his pioneering techniques in stereotactic surgery and is an elected fellow of a number of science and medical academies including the National Academy of Medical Sciences and the Indian Academy of Sciences. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1969.
Ralph Mobbs is an Australian neurosurgeon who specialises in spinal surgery. He operates at Prince of Wales Private and Public Hospital. He sees patients at his clinic and at an additional clinic in Bowral.
Empatica Inc. is an MIT Media Lab spinoff company born in Cambridge, Massachusetts, operating in Healthcare, providing AI-enabled tools to advance forecasting, monitoring, research, and treatment. Empatica produces medical-grade wearables, software and algorithms for the collection and interpretation of physiological data. Empatica's wearables, Embrace2 and E4, track physiological signals such as Heart Rate Variability, electrodermal activity, acceleration and movement, skin temperature, and autonomic arousal. Embrace2 has been cleared by the FDA as a seizure alerting solution for epilepsy patients with generalized tonic-clonic seizures. The E4 is used by researchers for real-time physiological data capture. The company is headquartered in Boston, MA with offices in Milan, Italy, and Seoul, South Korea.