David Sanders | |
---|---|
Born | |
Notable work | |
West Lafayette City Council | |
In office 2016–2022 | |
Alma mater | Yale College,University of California at Berkeley |
Scientific career | |
Fields | Molecular Virology |
Institutions | Purdue University |
Doctoral advisor | Daniel E. Koshland Jr. |
Other academic advisors | Richard C. Mulligan |
David Sanders is an associate professor of biological sciences at Purdue University. [1] He grew up in Teaneck,New Jersey, [2] [3] and then attended the Horace Mann School in Riverdale,New York. [4] He received his Bachelor of Science degree from Yale College in Molecular Biophysics and Biochemistry. [5] He conducted his Ph.D. research in Biochemistry with Daniel E. Koshland,Jr.,who was then editor of the journal Science,at the University of California at Berkeley. Sanders demonstrated that the response regulators in the two-component regulatory systems were phosphorylated on an aspartate residue and that they were protein phosphatases with a covalent intermediate. [6] [7] In 1995,he joined the Markey Center for Structural Biology at Purdue University. [8] In 2016,Sanders was elected to the West Lafayette City Council. He has opposed the plan to divert hundreds of millions of gallons of water from Tippecanoe County aquifers to the LEAP project in Boone County,and he sponsored the West Lafayette City Council resolution opposing the pipeline. [9] [10] [11]
He originated the idea of the "Molecule of the Year" feature in Science. [12] He was a visiting scientist at the University of California at San Francisco,and then a postdoctoral fellow at the Whitehead Institute for Biomedical Research,which is affiliated with MIT. It was there that he began his studies on the entry of viruses into cells with a focus on the inhibition of infection and applications to gene therapy.
He joined the Markey Center for Structural Biology at Purdue University in 1995,where he was the leader of the Molecular Virology program [13] and also a member of the Cancer Center. He was the discoverer of a biochemical reaction,thiol-disulfide exchange,that leads to the entry of cancer-causing retroviruses into cells. [14] [15] [16] He also is the primary inventor on two U.S. patents on novel gene-therapy delivery techniques. [17] [18]
His work on the Ebola virus led to his participation in the U.S. Defense Threat Reduction Agency's Biological Weapons Proliferation Prevention Program,a product of the Nunn-Lugar legislation. [19] His responsibilities included inspecting the Vector laboratory in Siberia,which was the site of biological-weapons development in the era of the Soviet Union. He has investigated the transmission of viruses from other animals,especially birds,to humans and has been invited to speak on ethics, [20] biodefense,evolution,gene therapy,vaccination and influenza viruses in public forums including regular interviews on WIBC in Indianapolis, [21]
He is a recipient of a National Science Foundation CAREER Award for his work on an enzyme that is involved in production of the greenhouse gas and potential energy source,methane [22] He is also an American Cancer Society Research Scholar. In 2003 he conducted his sabbatical research at the Weizmann Institute in Israel.
Sanders has been a vocal critic of the Science article authored by Felisa Wolfe-Simon and Paul Davies in which the discovery of arsenic-based life is claimed. [23] Sanders has argued that the original Science article on the arsenic bacteria should be retracted on the basis that the data in the paper were misrepresented in the article. [24] [25]
Sanders's work on the Ebola virus led to media interviews during the 2014 Ebola virus disease outbreak in Western Africa. He declared that there was little risk on infection for the individual American and asserted that the panic about the virus could be worse than the disease in the United States. [26] He was an early advocate of focusing on regional centers as places for treatment of Ebola virus victims in the United States [27] and asserted that patients should share their travel history whenever they meet with a medical provider,stating,"If you go to South America or East Asia there is a different ensemble of possible diseases associated with a set of symptoms,and the physician won't necessarily think about them if he isn't aware of where you've been traveling recently." [28] He opposed mandatory quarantines for asymptomatic patients that may have been exposed to Ebola virus. [29] Sanders wrote an article about his experience with the media including an encounter with Karl Rove. [30]
During the Coronavirus disease 2019 outbreak Sanders has been interviewed about the science behind public policy. [31] [32] He was reported to have criticized President Donald Trump for touting the use of chloroquine as a treatment for Coronavirus disease 2019. [33]
An article by Sanders was featured among a collection about keeping up with the contemporary academic literature. [34] He has also described new approaches to developing the literary skills of graduate students in the sciences [35] and rubrics for how to write (and how not to write) a scientific review article. [36]
Sanders is regarded as a scientific detective, [37] arguing that plagiarism is a serious academic issue that must be confronted. [38] He also maintains that guest authors are plagiarists and offers a simpler definition of plagiarism. [39]
According to The New York Times ,Sanders has been responsible for contacting scientific journals and obtaining corrections and retractions of articles by Carlo M. Croce. Sanders "has made claims of falsified data and plagiarism directly to scientific journals where more than 20 of Croce's papers have been published." [40] In 2017 Croce filed a defamation lawsuit against Sanders,who was quoted in The New York Times article that reported allegations of scientific misconduct against Croce. [41] In May 2020 Croce lost the defamation lawsuit against Sanders,with the presiding judge writing that "[d]iscovery has proved the existence of about 30 instances of fabrication or duplication" in Croce's research papers and that "Sanders has a knack for detecting image duplication and remembering the blots he sees reported in scientific journals." [42] The United States Court of Appeals for the Sixth Circuit of Appeal upheld the dismissal of the lawsuit,stating,"Journals have found research problems and plagiarism in articles coming from Croce’s lab. Sometimes,the problems were severe enough for the journals to publish corrections or expressions of concern (and sometimes to withdraw the paper). However you define 'scientific norms,' we know that academic journals felt some responsibility to alert the scientific community about problems in some of Croce’s papers. That suggests the papers contained problems outside the range of acceptable research and publishing practices. Thus,the statement that people in Croce’s lab have violated scientific norms is substantially true." [43] Sanders was interviewed about his experience defending himself in the suit wherein he recommended collaborations between scientific whistleblowers. [44]
Sanders authored an article on reforming grant peer review with the goal of reducing bias. [45]
As Chair of the Purdue University Senate,Sanders published a statement of academic principles. [46]
In 2002,he unsuccessfully challenged Republican State Senator Ron Alting in District 22. [47]
Sanders was the Democratic candidate for Congress in the 4th District of Indiana in 2004,2006,and 2010,losing to Steve Buyer in the first two elections and to Todd Rokita in the third. [48] [49] [50] Years later,in a discussion about gerrymandering,Sanders called the seat he ran for in Indiana's 4th Congressional District as having been drawn so that it was "No Republican Left Behind." [51]
Sanders was elected by Democrats of the 4th Congressional District of Indiana to serve as a delegate pledged to Barack Obama at the 2008 Democratic National Convention. [52]
On November 3,2015,Sanders was elected as a City Councilor At-Large for West Lafayette [53] and on November 5,2019,David Sanders was reelected. [54]
On January 25,2022,Sanders announced his candidacy for Indiana State Senator District 23 stating that "he hoped to help rural counties feel less neglected by the state government.". [55] His opponent in the election backed out of the only scheduled debate in the race. [56]
Sanders began his term on the Council in 2016,after a campaign in which he promised "careful oversight","transparency" and "quantitative analytical skills". [57]
In 2017,Sanders introduced and passed a resolution declaring West Lafayette a "machaseh" —that is,a refuge,for immigrants. The resolution was debated at multiple meetings and was crafted to adhere to state law which prohibits sanctuary cities. [58] [59]
In 2017,Sanders took a knee during a city council meeting immediately after the pledge of allegiance. He later wrote an op-ed explaining his reasons which included an "assault on the constitutional right to free speech",“Indiana voter ID laws (the new poll taxes)”,“the war on drugs”and “the very name of our state”as a reminder of the unfair treatment of Native Americans. [60]
In 2018,Sanders sponsored a resolution to encourage businesses to stop using plastic straws and utensils,which passed the city council. [61]
In 2021,Sanders sponsored an ordinance to prohibit unlicensed therapists from practicing conversion therapy in West Lafayette. It was withdrawn because of the threat of a lawsuit. [62]
Sanders has made personal privacy a focus of his city council service and he was the sponsor of an ordinance banning facial recognition surveillance technology that twice passed the city council. It was vetoed by the mayor. [63] [64]
Sanders opposed a tax abatement for Rolls-Royce because he regarded the Economic Revitalization Zone necessary for the abatement to be inconsistent with Indiana law and questioned whether the company needed the tax abatement. He also expressed his concern about providing tax abatements to a company that had been involved in the largest bribery scandal in UK history and was fined by the United States in 2017 for bribery of foreign officials. [65]
Sanders founded the "Stop the Water Steal" organization "in opposition to a state-sponsored project that would pump as much as 100 million gallons of water per day from aquifers connected to the Wabash River to an advanced manufacturing park in Boone County." [66]
Purdue University is a public land-grant research university in West Lafayette,Indiana,and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and money to establish a college of science,technology,and agriculture in his name. The first classes were held on September 16,1874,with six instructors and 39 students.
Lafayette is a city in and is the county seat of Tippecanoe County,Indiana,United States,located 63 miles (101 km) northwest of Indianapolis and 125 miles (201 km) southeast of Chicago. West Lafayette,on the other side of the Wabash River,is home to Purdue University,which contributes significantly to both communities. Together,Lafayette and West Lafayette form the core of the Lafayette metropolitan area,which had a population of 224,709 in the 2021 US Census Bureau estimates.
West Lafayette is a city in Wabash Township,Tippecanoe County,Indiana,United States,approximately 65 miles (105 km) northwest of the state capital of Indianapolis and 113 miles (182 km) southeast of Chicago. West Lafayette is directly across the Wabash River from its sister city,Lafayette. As of the 2020 census,its population was 44,595. A college town,it is the most densely populated city in Indiana and is home to Purdue University.
John Purdue was a wealthy American industrialist in Lafayette,Indiana,and the primary original benefactor of Purdue University.
WBAA and WBAA-FM (101.3 FM) are jointly operated non-commercial educational radio stations licensed to West Lafayette,Indiana,United States,both serving the Lafayette metro area and the Indianapolis area with public radio formats. The stations were founded by Purdue University,but in 2022,100 years after WBAA's start,ownership was transferred to Metropolitan Indianapolis Public Media,Inc. (MIPM),which also owns WFYI radio and television in Indianapolis. Both stations originate from studios in the Edward C. Elliott Hall of Music on the Purdue campus,with transmitter sites south of Lafayette at the Throckmorton Purdue Agricultural Center.
Loeb Stadium was a stadium in Columbian Park in Lafayette,Indiana,United States. It was primarily used for baseball and had most recently been the home of the Lafayette Aviators of the Prospect League.
Daniel Edward Koshland Jr. was an American biochemist. He reorganized the study of biology at the University of California,Berkeley,and was the editor of the leading U.S. science journal,Science,from 1985 to 1995. He was a member of the United States National Academy of Sciences,the American Academy of Arts and Sciences,and the American Philosophical Society.
Otto Frederick Hunziker was a pioneer in the American and international dairy industry,as both an educator and a technical innovator. Hunziker was born and raised in Switzerland,emigrated to the U.S.,and studied at Cornell University. He started and developed the dairy program at Purdue University when such programs were at their infancy. At this same time,Hunziker was heavily involved with the development of the American Dairy Science Association (ADSA) and the standardization and improvement of many dairy tests and processes. Hunziker wrote several of the leading dairy processing texts,which continue to be cited. After leaving Purdue University,Hunziker managed research and operations at a large,national condensary,continued to drive ADSA's standardization and publishing efforts,represented the U.S. at international dairy congresses,and facilitated dairy industry improvements across the globe.
DiaGrid is a large,multicampus distributed research computing network utilizing the HTCondor system and centered at Purdue University in West Lafayette,Indiana. In 2012,it included nearly 43,000 processors representing 301 teraflops of computing power. DiaGrid received a Campus Technology Innovators Award from Campus Technology magazine and an IDG InfoWorld 100 Award in 2009 and was employed at the SC09 supercomputing conference in Portland,Ore.,to capture nearly 150 days of compute time for science jobs.
Elmer Harold Burnham was an American football coach and all-around athlete,known particularly for his basketball skills both in college and in amateur YMCA play in Indiana. He was the head football coach at Purdue University in 1942 and 1943. Burnham's 1943 Purdue squad went 9–0 and shared the Big Ten Conference title with Michigan. From 1944 to 1960,Burnham served as the head coach at the University of Rochester,where he compiled a record of 82–48–6 in 17 seasons. Burnham served as Purdue's freshman football coach for seven years before assuming the role as varsity head coach in 1942. Before coming to Purdue,Burnham coached football at Central High School in South Bend,Indiana,for 16 seasons,tallying a mark of 118–30–8.
Brandt Hershman is an American politician and a former Republican state senator for Indiana. He served from 2000 to 2018. He is married to Lisa Hershman.
Randy Truitt is a former member of the Indiana House of Representatives representing District 26 which includes portions of Tippecanoe and Warren County. He was first elected to the Indiana House of Representatives in 2008. Prior to 2008,he was a member of the West Lafayette,Indiana City Council. After eight years in state government,Truitt did not re-run for election in 2016 and returned his focus to his real estate firm.
Ronald J. Alting is a member of the Indiana State Senate representing Senate District 22,which contains most of Tippecanoe County. He is a Republican. Alting was first elected to the Indiana State Senate in 1998. Prior to that,Alting served as a member of the Lafayette,Indiana City Council.
Carlo Maria Croce is an Italian–American professor of medicine at Ohio State University,specializing in oncology and the molecular mechanisms underlying cancer. Croce and his research have attracted public attention because of multiple allegations of scientific misconduct.
Henry Wright Marshall Sr. was an American businessperson and politician. He is known for being the founder of the Lafayette (Indiana) Journal &Courier,Speaker of the Indiana House of Representatives,and acting president of Purdue University.
David Marshall Blough is an American football quarterback for the Detroit Lions of the National Football League (NFL). He played college football at Purdue and signed with the Cleveland Browns as an undrafted free agent in 2019. Following an injury to Matthew Stafford and Jeff Driskel,Blough assumed the starting role for the final five games of the Detroit Lions' 2019 season. He has also been a member of the Minnesota Vikings. He is the husband of Colombian-American hurdler Melissa Gonzalez.
David A. Reingold is an American sociologist and higher education administrator. He is the Senior Vice President for Policy Planning and the Justin S. Morrill Dean of the College of Liberal Arts at Purdue University on the West Lafayette campus where he is a professor of sociology.
Charles Addison Bouman Jr. is the Showalter Professor of Electrical and Computer Engineering and Biomedical Engineering at Purdue University,where he has taught since 1989. His research focuses on applications of image processing in various contexts,including medicine,materials science,and consumer imaging. His work led to the development of the first commercial CT scan technology to use model-based iterative reconstruction. He is a co-inventor on over fifty patents in the field of consumer imaging. He is a member of the National Academy of Inventors,as well as a fellow of the Institute of Electrical and Electronics Engineers,the American Institute for Medical and Biological Engineering,the Society for Imaging Science and Technology,and SPIE. He was formerly the editor-in-chief of IEEE Transactions on Image Processing.
George Matthew Karlaftis III is a Greek professional American football defensive end for the Kansas City Chiefs of the National Football League (NFL). He was born in Athens and grew up as a multi-sport athlete playing football,track and field,basketball,and water polo,the latter of which he played with the Greek national team.
The Ouabache Sculpture is a public artwork located in Lafayette,Tippecanoe County in the US state of Indiana. Located on a grassy plot between adjacent lanes of the Harrison Street Bridge and lying just east of the Wabash River,the sculpture is kinetic and will move by being pushed by the wind. The sculpture is the largest work of public art in Lafayette and is described as "an early example of the modern era" of art. Details of the Ouabache Sculpture are listed in the Art Inventories Catalog published by the Smithsonian American Art Museum.
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