David Sheffield Bell

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David Sheffield Bell is an American physician who has done extensive research on the clinical aspects of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). He has also conducted evaluations and research in pediatric ME/CFS and written numerous articles about the condition. [1] [2]

Contents

Bell is retired [3] from a private practice in general medicine in the town of Lyndonville, New York which he had started in 1979. [4] Bell also served as Clinical Associate Professor of Pediatrics at the State University of New York at Buffalo, in Buffalo, New York. [5]

Training

Bell is a graduate of Harvard University, class of 1967, with an AB degree in English Literature. He graduated in 1971 from Boston University with an MD degree, and in 1976 completed post-doctoral training in pediatrics including Pediatric Behavior and Developmental Disorders. [6] [7]

Work on chronic fatigue syndrome

Bell's interest in ME/CFS began in 1985 when an apparent cluster outbreak of 216 persons occurred in his rural community in upstate New York. He has written extensively on the condition, including a thirteen-year follow-up study of the children who became ill during the original outbreak. [2] [8]

Bell was involved in identifying the outbreak in Lyndonville, New York, of what was known at the time as chronic Epstein-Barr virus (now more commonly referred to as ME/CFS). [4] When Bell was interviewed about the outbreak in a 1996 Prime Time Live episode, the reporter described Bell's appeal to the Centers for Disease Control and Prevention (CDC) for help with the illness, but Bell says the CDC didn't mention a similar outbreak in Lake Tahoe, which he learned about later. He met with other ME/CFS researchers at a 1987 conference, and joined an investigation with researchers Paul Cheney and Elaine DeFreitas involving a possible retrovirus association with chronic fatigue syndrome. [9] In 1990, the researchers presented evidence they found DNA sequences very similar to a known human retrovirus in some ME/CFS patients, at a conference in Kyoto, Japan. [10] [11] Their study was later published in the Proceedings of the National Academy of Sciences. [12] A reporter on Prime Time Live stated the announcement made headlines all over the world. The CDC first ignored their findings, [9] then later conducted a study and published a paper that refuted the hypothesis. [13]

Bell wrote The Doctor's Guide to Chronic Fatigue Syndrome, which was published in 1995. The book, which also refers to ME/CFS as "chronic fatigue/immune dysfunction syndrome," or CFIDS, describes Bell's CFIDS disability scale. [14] Various publications have used or proposed Bell's scale which is similar to the Karnofsky scale, for the documentation of severity of symptoms in chronic fatigue syndrome. [15] [16] [17] [18]

In the 2000 ME/CFS documentary, I Remember Me, Bell appeared in an interview recounting his experiences during the Lyndonville outbreak. [19] [20]

In 2003, Secretary of Health and Human Services Tommy Thompson designated Bell chairperson of the Chronic Fatigue Syndrome Advisory Committee (CFSAC), a panel of 11 experts that provides advice and recommendations to the Secretary of Health and Human Services "on the development and implementation of programs to inform the public; health care professionals; and the biomedical, academic, and research communities about advances related to CFS." [1] [21] [22]

Bell also served as a board member of the International Association for Chronic Fatigue Syndrome/ME (IACFS/ME), [23] a professional organization of about 300 members that advocates for the concerns of CFS researchers and clinicians around the world. [24]

Bell has retired from private practice, but in 2011 was still doing research on the cause of the illness of ME/CFS patients in Lyndonville NY. [3]

Bell currently serves on the Open Medicine Foundation Scientific Advisory Board, which is committed to ending ME/CFS. [25]

Related Research Articles

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Clinical descriptions of ME/CFS vary. Different groups have produced sets of diagnostic criteria that share many similarities. The biggest differences between criteria are whether post-exertional malaise (PEM) is required, and the number of symptoms needed. The pathology of ME/CFS is unknown, and it can be a difficult condition to diagnose because there is no standard test, many symptoms are non-specific, and because doctors and patients may be unfamiliar with post-exertional malaise. Subgroup analysis suggests that, depending on the applied definition, CFS may represent a variety of conditions rather than a single disease entity.

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<span class="mw-page-title-main">Post-exertional malaise</span> Worsening of symptoms with activity

Post-exertional malaise (PEM), sometimes referred to as post-exertional symptom exacerbation (PESE), is a worsening of symptoms that occurs after minimal exertion. It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID. PEM is often severe enough to be disabling, and is triggered by ordinary activities that healthy people tolerate. Typically, it begins 12–48 hours after the activity that triggers it, and lasts for days, but this is highly variable and may persist much longer. Management of PEM is symptom-based, and patients are recommended to pace their activities to avoid triggering PEM.

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<span class="mw-page-title-main">2-day CPET</span> Medical test for post-exertional malaise

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References

  1. 1 2 "Secretary Thompson Names New Members To Chronic Fatigue Syndrome Advisory Committee". U.S. Department of Health & Human Services. October 1, 2003. Archived from the original on June 10, 2010. Retrieved 2010-10-13.
  2. 1 2 "David S. Bell, M.D." International Association for CFS/ME. Archived from the original on 2009-05-23. Retrieved 2009-01-11.
  3. 1 2 Bellini J. (March 5, 2011). "The Puzzle of Chronic Fatigue". Video. WSJ. Retrieved 2011-03-05.
  4. 1 2 Hager, Mary; Joseph, Nadine (November 12, 1990). "Chronic Fatigue Syndrome A Modern Medical Mystery". Newsweek.
  5. ↑ Jason L.; et al. (May 2006). "A Pediatric Case Definition for Myalgic Encephalomyelitis and Chronic Fatigue Syndrome". Journal of Chronic Fatigue Syndrome. 13 (2/3): 1–44. CiteSeerX   10.1.1.516.4887 . doi:10.1300/J092v13n02_01.
  6. ↑ "About David S. Bell". Archived from the original on 2008-12-09. Retrieved 2009-01-11.
  7. ↑ "Faculty Biographies". International Association for CFS/ME. Archived from the original on 2011-07-26. Retrieved 2009-05-09.
  8. ↑ Bell DS, Jordan K, Robinson M (May 2001). "Thirteen-year follow-up of children and adolescents with chronic fatigue syndrome". Pediatrics. 107 (5): 994–8. CiteSeerX   10.1.1.612.5480 . doi:10.1542/peds.107.5.994. PMID   11331676.
  9. 1 2 Sam Donaldson, Nancy Snyderman, Paul Cheney, David Bell, Elaine DeFreitas, Hillary Johnson, PWC's, Paul Pollard, Mrs. Dailor, Philip Lee (1996-03-27). Sick & Tired (Television). ABC News.
  10. ↑ Palca J (14 September 1990). "Does a retrovirus explain fatigue syndrome puzzle?". Science. 249 (4974): 1240–12. Bibcode:1990Sci...249.1240P. doi:10.1126/science.2399461. PMID   2399461.
  11. ↑ Altman, Lawrence K. (September 5, 1990). "Virus Found That May Be Linked To a Debilitating Fatigue Ailment". news article. The New York Times. Retrieved 2009-02-24.
  12. ↑ DeFreitas E, Hilliard B, Cheney PR, et al. (April 1991). "Retroviral sequences related to human T-lymphotropic virus type II in patients with chronic fatigue immune dysfunction syndrome". Proc. Natl. Acad. Sci. U.S.A. 88 (7): 2922–6. Bibcode:1991PNAS...88.2922D. doi: 10.1073/pnas.88.7.2922 . PMC   51352 . PMID   1672770.
  13. ↑ Centers for Disease Control and Prevention (CDC) (March 1993). "Inability of retroviral tests to identify persons with chronic fatigue syndrome, 1992". MMWR Morb. Mortal. Wkly. Rep. 42 (10): 183, 189–90. PMID   8446093 . Retrieved 2009-02-23.
  14. ↑ Bell, David (1995). The doctor's guide to chronic fatigue syndrome: understanding, treating, and living with CFIDS. Reading, Mass: Addison-Wesley Pub. Co. pp.  122–123. ISBN   978-0-201-40797-6.
  15. ↑ Assessing and Documenting Impairment in CFS (PDF). Centers for Disease Control and Prevention U.S. Department of Health & Human Services. 2007. Retrieved 2009-02-10.
  16. ↑ ME/CFS Guidelines Myalgic Encephalopathy (ME)/ Chronic Fatigue Syndrome (CFS) Management Guidelines for General Practitioners. South Australian Department of Human Services. 2004. ISBN   978-0-7308-9334-9.
  17. ↑ Sarah Myhill; Norman E. Booth; John McLaren-Howard (2009). "Chronic fatigue syndrome and mitochondrial dysfunction" (PDF). Int J Clin Exp Med. 2 (1): 1–16. PMC   2680051 . PMID   19436827 . Retrieved 2009-01-26.
  18. ↑ Chronic Fatigue Syndrome: From Diagnosis to Management CME/CE (pdf). Medscape, LLC. 2008. Retrieved 2009-04-19.[ permanent dead link ]
  19. ↑ "I Remember Me". Documentary. Retrieved 2009-05-09.
  20. ↑ "I Remember Me" (PDF). press release. ZEITGEIST FILMS. Archived from the original (PDF) on 2010-12-02. Retrieved 2009-01-09.
  21. ↑ Bell, D (2005). "Recognizing Chronic Fatigue Syndrome in Teens". Internal Medicine News. 38 (9): 15. doi:10.1016/S1097-8690(05)70626-0 . Retrieved 2009-02-07.[ permanent dead link ]
  22. ↑ "SOCIAL SECURITY ADMINISTRATION FISCAL YEAR 2008 Justification of Estimates for Appropriations Committees" (PDF). U.S. Social Security Administration. February 2007. Archived from the original (PDF) on 2011-05-29. Retrieved 2009-02-07.
  23. ↑ "Bulletin of the International Association for CFS/ME". International Association for CFS/ME. Spring 2006. Archived from the original on 2009-05-25. Retrieved 2009-01-11.
  24. ↑ Friedberg F, Sohl S, Schmeizer B (August 2007). "Publication trends in chronic fatigue syndrome: comparisons with fibromyalgia and fatigue: 1995-2004". J Psychosom Res. 63 (2): 143–6. doi:10.1016/j.jpsychores.2007.03.003. PMID   17662750.
  25. ↑ "Open Medicine Foundation Scientific Advisory Board" . Retrieved 2018-07-03.

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