Down syndrome cell adhesion molecule like 1

DSCAML1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1VA9
Identifiers
Aliases	DSCAML1 , Dscaml1, 4921507G06Rik, 4930435C18Rik, BB239540, mKIAA1132, DSCAM2, DS cell adhesion molecule like 1
External IDs	OMIM: 611782; MGI: 2150309; HomoloGene: 79549; GeneCards: DSCAML1; OMA:DSCAML1 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q23.3 Start 117,427,772 bp [1] End 117,817,525 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A5.2 Start 45,337,926 bp [2] End 45,665,010 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium C1 segment postcentral gyrus entorhinal cortex prefrontal cortex hippocampus proper corpus callosum ganglionic eminence Brodmann area 46 superior frontal gyrus Top expressed in neural layer of retina subiculum Rostral migratory stream pretectal area piriform cortex temporal lobe amygdala dentate gyrus anterior amygdaloid area olfactory bulb More reference expression data BioGPS n/a
Gene ontology Molecular function protein homodimerization activity cell-cell adhesion mediator activity Cellular component integral component of membrane cell surface cell junction plasma membrane synapse membrane extracellular space axon Biological process embryonic skeletal system morphogenesis cell fate determination central nervous system development brain development cell adhesion dorsal/ventral pattern formation axonogenesis nervous system development homophilic cell adhesion via plasma membrane adhesion molecules axon guidance dendrite self-avoidance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57453 114873 Ensembl ENSG00000177103 ENSMUSG00000032087 UniProt Q8TD84 Q4VA61 RefSeq (mRNA) NM_020693 NM_001367904 NM_001367905 NM_001081270 NM_029039 RefSeq (protein) NP_065744 NP_001354833 NP_001354834 NP_001074739 Location (UCSC) Chr 11: 117.43 – 117.82 Mb Chr 9: 45.34 – 45.67 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Down syndrome cell adhesion molecule like 1 is a protein in humans that is encoded by the DSCAML1 gene. ^[5]

See also

• DSCAM, Down syndrome cell adhesion molecule
• Fibronectin type III domain
• Immunoglobulin superfamily

References

1. GRCh38: Ensembl release 89: ENSG00000177103 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032087 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "DSCAML1 DS cell adhesion molecule like 1 [ Homo sapiens (human) ]" . Retrieved 2012-11-29.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Down syndrome cell adhesion molecule-like protein 1