EMP1

EMP1
Identifiers
Aliases	EMP1 , CL-20, EMP-1, TMP, epithelial membrane protein 1
External IDs	OMIM: 602333 MGI: 107941 HomoloGene: 1088 GeneCards: EMP1
Gene location (Human)
Chr.	Chromosome 12 (human)
End	13,219,941 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	135,360,171 bp
RNA expression pattern
	Top expressed in
	cavity of mouth; ; amniotic fluid; ; synovial joint; ; body of tongue; ; gums; ; stromal cell of endometrium; ; vena cava; ; human penis; ; vulva; ; vagina;
	Top expressed in
	corneal stroma; ; conjunctival fornix; ; belly cord; ; ankle joint; ; left lung lobe; ; skin of back; ; dermis; ; sciatic nerve; ; ciliary body; ; atrioventricular valve;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	plasma membrane ; membrane ; integral component of membrane ;
Biological process	multicellular organism development ; bleb assembly ; cell population proliferation ; cell death ; epidermis development ;
	Sources:Amigo / QuickGO
Orthologs
	2012
	13730
	ENSG00000134531
	ENSMUSG00000030208
	P54849
	P47801
	NM_001423
	NM_001288627 ; NM_001288628 ; NM_010128
	NP_001414
	NP_001275556 ; NP_001275557 ; NP_034258
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 02, 2023

Epithelial membrane protein 1 is a protein that in humans is encoded by the EMP1 gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000134531 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030208 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins". Gene. 183 (1–2): 69–75. doi:10.1016/S0378-1119(96)00475-1. PMID 8996089.
↑ Chen Y, Medvedev A, Ruzanov P, Marvin KW, Jetten AM (May 1997). "cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family". Genomics. 41 (1): 40–8. doi:10.1006/geno.1997.4524. PMID 9126480.
↑ "Entrez Gene: EMP1 epithelial membrane protein 1".

Jain A, Tindell CA, Laux I, et al. (2005). "Epithelial membrane protein-1 is a biomarker of gefitinib resistance". Proc. Natl. Acad. Sci. U.S.A. 102 (33): 11858–63. Bibcode:2005PNAS..10211858J. doi: 10.1073/pnas.0502113102 . PMC 1187965 . PMID 16087880.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wang HT, Kong JP, Ding F, et al. (2003). "Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNA Microarray". World J. Gastroenterol. 9 (3): 392–8. doi:10.3748/wjg.v9.i3.392. PMC 4621547 . PMID 12632483.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Wang HT, Liu ZH, Wang XQ, Wu M (2003). "[Effect of EMP-1 gene on human esophageal cancer cell line]". AI Zheng. 21 (3): 229–32. PMID 12451984.
Liehr T, Kuhlenbäumer G, Wulf P, et al. (1999). "Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3". Genomics. 58 (1): 106–8. doi:10.1006/geno.1999.5803. PMID 10331954.
Schiemann S, Rückels M, Engelholm LH, et al. (1997). "Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family". Anticancer Res. 17 (1A): 13–20. PMID 9066625.
Lobsiger CS, Magyar JP, Taylor V, et al. (1997). "Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1". Genomics. 36 (3): 379–87. doi:10.1006/geno.1996.0482. PMID 8884260.
Ruegg CL, Wu HY, Fagnoni FF, et al. (1996). "B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain". J. Immunol. 157 (1): 72–80. PMID 8683158.
Marvin KW, Fujimoto W, Jetten AM (1996). "Identification and characterization of a novel squamous cell-associated gene related to PMP22". J. Biol. Chem. 270 (48): 28910–6. doi: 10.1074/jbc.270.48.28910 . PMID 7499420.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000134531 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030208 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8996089-5] Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins". Gene. 183 (1–2): 69–75. doi:10.1016/S0378-1119(96)00475-1. PMID 8996089.

[pmid9126480-6] Chen Y, Medvedev A, Ruzanov P, Marvin KW, Jetten AM (May 1997). "cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family". Genomics. 41 (1): 40–8. doi:10.1006/geno.1997.4524. PMID 9126480.

[entrez-7] "Entrez Gene: EMP1 epithelial membrane protein 1".

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EMP1

Related Research Articles

References

Further reading