ERGIC3

ERGIC3
Identifiers
Aliases	ERGIC3 , C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84, dJ477O4.2, ERGIC and golgi 3, C2orf47
External IDs	OMIM: 616971 MGI: 1913616 HomoloGene: 5289 GeneCards: ERGIC3
Gene location (Human)
Chr.	Chromosome 20 (human)
End	35,557,634 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	155,860,199 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; stromal cell of endometrium; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; canal of the cervix; ; minor salivary gland; ; body of pancreas; ; islet of Langerhans; ; body of stomach; ; rectum;
	Top expressed in
	molar; ; yolk sac; ; external carotid artery; ; internal carotid artery; ; arcuate nucleus; ; supraoptic nucleus; ; superior frontal gyrus; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; neural tube;
	More reference expression data
	More reference expression data
Orthologs
	51614
	66366
	ENSG00000125991
	ENSMUSG00000005881
	Q9Y282
	Q9CQE7
	NM_015966 ; NM_198398
	NM_025516 ; NM_001356413 ; NM_001356414
	NP_057050 ; NP_938408
	NP_079792 ; NP_001343342 ; NP_001343343
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 05, 2022

Endoplasmic reticulum-Golgi intermediate compartment protein 3 is a protein that in humans is encoded by the ERGIC3 gene.^[5]^[6] It has been reported to be regulated by micro RNAs and may be important in a cancer.^[7]^[8]

Related Research Articles

Protein ERGIC-53 also known as ER-Golgi intermediate compartment 53 kDa protein or lectin mannose-binding 1 is a protein that in humans is encoded by the LMAN1 gene.

Protein transport protein Sec61 subunit beta is a protein that in humans is encoded by the SEC61B gene.

Nucleobindin-1 (NUCB1), also known as calnuc, is a protein that in humans is encoded by the NUCB1 gene.

DnaJ homolog subfamily B member 11 is a protein that in humans is encoded by the DNAJB11 gene.

Protein SEC13 homolog is a protein that in humans is encoded by the SEC13 gene.

Protein transport protein Sec61 subunit alpha isoform 1 is a protein that in humans is encoded by the SEC61A1 gene.

Vesicle-trafficking protein SEC22b is a protein that in humans is encoded by the SEC22B gene.

BET1 homolog is a protein that in humans is encoded by the BET1 gene.

ER lumen protein retaining receptor 2 is a protein that in humans is encoded by the KDELR2 gene.

Endoplasmic reticulum resident protein 44 (ERp44) also known as thioredoxin domain-containing protein 4 (TXNDC4) is a protein that in humans is encoded by the ERP44 gene.

Nucleobindin-2 is a protein that when found in humans is encoded by the NUCB2 gene.

RAD50-interacting protein 1 is a protein that in humans is encoded by the RINT1 gene.

Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) is a gene located on human chromosome 12p11. It encodes a protein of 377 amino acid residues. ERGIC2 protein is also known as PTX1, CDA14 or Erv41.

Zinc finger FYVE domain-containing protein 1 is a protein that in humans is encoded by the ZFYVE1 gene.

Vesicular integral-membrane protein VIP36 is a protein that in humans is encoded by the LMAN2 gene.

Vesicle-trafficking protein SEC22a is a protein that in humans is encoded by the SEC22A gene.

ER lumen protein retaining receptor 3 is a protein that in humans is encoded by the KDELR3 gene.

Ras-related protein Rab-37 is a protein that in humans is encoded by the RAB37 gene.

SEC23-interacting protein is a protein that in humans is encoded by the SEC23IP gene.

Chloride channel CLIC-like 1 also known as CLCC1 is a human gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000125991 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005881 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.
↑ "Entrez Gene: ERGIC3 ERGIC and golgi 3".
↑ Zhang, Ling-yun; Liu, Min; Li, Xin; Tang, Hua (2013). "miR-490-3p Modulates Cell Growth and Epithelial to Mesenchymal Transition of Hepatocellular Carcinoma Cells by Targeting Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 3 (ERGIC3)". Journal of Biological Chemistry. 288 (6): 4035–4047. doi: 10.1074/jbc.M112.410506 . ISSN 0021-9258. PMC 3567655 . PMID 23212913.
↑ Lin, Qing-Hai; Zhang, Kui-Dong; Duan, He-Xian; Liu, Min-Xia; Wei, Wan-Li; Cao, Yi (2015). "ERGIC3, which is regulated by miR-203a, is a potential biomarker for non-small cell lung cancer". Cancer Science. 106 (10): 1463–1473. doi:10.1111/cas.12741. ISSN 1347-9032. PMC 4638005 . PMID 26177443.

Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID 11780052.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Scanlan MJ, Gout I, Gordon CM, et al. (2003). "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression". Cancer Immun. 1: 4. PMID 12747765.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi: 10.1074/jbc.M406644200 . PMID 15308636.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi: 10.1093/dnares/12.2.117 . PMID 16303743.
Nishikawa M, Kira Y, Yabunaka Y, Inoue M (2007). "Identification and characterization of endoplasmic reticulum-associated protein, ERp43". Gene. 386 (1–2): 42–51. doi:10.1016/j.gene.2006.06.030. PMID 17020792.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000125991 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005881 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10810093-5] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.

[entrez-6] "Entrez Gene: ERGIC3 ERGIC and golgi 3".

[ZhangLiu2013-7] Zhang, Ling-yun; Liu, Min; Li, Xin; Tang, Hua (2013). "miR-490-3p Modulates Cell Growth and Epithelial to Mesenchymal Transition of Hepatocellular Carcinoma Cells by Targeting Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 3 (ERGIC3)". Journal of Biological Chemistry. 288 (6): 4035–4047. doi: 10.1074/jbc.M112.410506 . ISSN 0021-9258. PMC 3567655 . PMID 23212913.

[LinZhang2015-8] Lin, Qing-Hai; Zhang, Kui-Dong; Duan, He-Xian; Liu, Min-Xia; Wei, Wan-Li; Cao, Yi (2015). "ERGIC3, which is regulated by miR-203a, is a potential biomarker for non-small cell lung cancer". Cancer Science. 106 (10): 1463–1473. doi:10.1111/cas.12741. ISSN 1347-9032. PMC 4638005 . PMID 26177443.

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ERGIC3

Related Research Articles

References

Further reading