ERLEC1

ERLEC1
Identifiers
Aliases	ERLEC1 , C2orf30, CIM, CL24936, CL25084, HEL117, XTP3-B, XTP3TPB, endoplasmic reticulum lectin 1
External IDs	OMIM: 611229 MGI: 1914003 HomoloGene: 9247 GeneCards: ERLEC1
Gene location (Human)
Chr.	Chromosome 2 (human)
End	53,833,038 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	30,954,335 bp
RNA expression pattern
	Top expressed in
	pancreatic epithelial cell; ; endothelial cell; ; tibia; ; tibialis anterior muscle; ; pancreatic ductal cell; ; corpus epididymis; ; middle temporal gyrus; ; islet of Langerhans; ; parotid gland; ; seminal vesicula;
	Top expressed in
	seminal vesicula; ; fossa; ; parotid gland; ; islet of Langerhans; ; supraoptic nucleus; ; retinal pigment epithelium; ; calvaria; ; lacrimal gland; ; Epithelium of stomach; ; ciliary body;
	More reference expression data
	n/a
Gene ontology
Molecular function	unfolded protein binding ; protein binding ;
Cellular component	endoplasmic reticulum lumen ; endoplasmic reticulum quality control compartment ; endoplasmic reticulum ;
Biological process	ERAD pathway ; negative regulation of retrograde protein transport, ER to cytosol ; transmembrane transport ; ubiquitin-dependent ERAD pathway ; retrograde protein transport, ER to cytosol ;
	Sources:Amigo / QuickGO
Orthologs
	27248
	66753
	ENSG00000068912
	ENSMUSG00000020311
	Q96DZ1
	Q8VEH8
	NM_001127397 ; NM_001127398 ; NM_015701
	NM_025745
	NP_001120869 ; NP_001120870 ; NP_056516
	NP_080021
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Endoplasmic reticulum lectin 1 is a protein that in humans is encoded by the ERLEC1 gene.^[5]^[6]^[7]^[8]^[9]

Related Research Articles

Ras-related protein Rab-6A is a protein that in humans is encoded by the RAB6A gene located in the eleventh chromosome. Its main function is the regulation of protein transport from the Golgi complex to the endoplasmic reticulum and the exocytosis along with the microtubules.

PHD finger protein 10 is a protein that in humans is encoded by the PHF10 gene.

Conserved oligomeric Golgi complex subunit 3 is a protein that in humans is encoded by the COG3 gene.

Conserved oligomeric Golgi complex subunit 7 is a protein that in humans is encoded by the COG7 gene.

Thioredoxin domain-containing protein 12 is a protein that in humans is encoded by the TXNDC12 gene.

Mitochondrial fission regulator 1 like is a protein that in humans is encoded by the MTFR1L gene.

Zinc finger MIZ domain-containing protein 1 is a protein that in humans is encoded by the ZMIZ1 gene.

Transmembrane and coiled-coil domain-containing protein 1 is a protein that in humans is encoded by the TMCO1 gene.

UBX domain-containing protein 11 is a protein that in humans is encoded by the UBXN11 gene.

Low-density lipoprotein receptor-related protein 10 is a protein that in humans is encoded by the LRP10 gene.

Zinc transporter ZIP3 is a protein that in humans is encoded by the SLC39A3 gene.

ER degradation-enhancing alpha-mannosidase-like 2 is an enzyme that in humans is encoded by the EDEM2 gene.

Arginine vasopressin-induced protein 1 is a protein that in humans is encoded by the AVPI1 gene.

Iron-sulfur cluster assembly 1 homolog, mitochondrial is an evolutionarily highly conserved protein for the biogenesis of iron-sulfur cluster across species. In humans it is encoded by the ISCA1 gene.

Calcium-binding protein 8 is a protein that in humans is encoded by the CALN1 gene. Alternative splicing results in multiple transcript variants.

U3 small nucleolar ribonucleoprotein protein IMP4 is a protein that in humans is encoded by the IMP4 gene.

SAC3 domain-containing protein 1 is a protein that in humans is encoded by the SAC3D1 gene.

Uncharacterized protein C12orf43 is a protein that in humans is encoded by the C12orf43 gene.

Caspase activity and apoptosis inhibitor 1 is a protein that in humans is encoded by the CAAP1 gene.

Rho GTPase-activating protein 19 is an enzyme that in humans is encoded by the ARHGAP19 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000068912 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020311 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
↑ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
↑ Cruciat CM, Hassler C, Niehrs C (2006). "The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition". J. Biol. Chem. 281 (18): 12986–93. doi: 10.1074/jbc.M511872200 . PMID 16531414.
↑ Christianson JC, Shaler TA, Tyler RE, Kopito RR (2008). "OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD". Nat. Cell Biol. 10 (3): 272–82. doi:10.1038/ncb1689. PMC 2757077 . PMID 18264092.
↑ "Entrez Gene: C2orf30 chromosome 2 open reading frame 30".

ERLEC1

Related Research Articles

References

Further reading