ESAM (gene)

ESAM
Identifiers
Aliases	ESAM , W117m, endothelial cell adhesion molecule
External IDs	OMIM: 614281 MGI: 1916774 HomoloGene: 12316 GeneCards: ESAM
Gene location (Human)
Chr.	Chromosome 11 (human)
End	124,762,290 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	37,449,615 bp
RNA expression pattern
	Top expressed in
	right lung; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; upper lobe of left lung; ; right coronary artery; ; popliteal artery; ; left coronary artery; ; subcutaneous adipose tissue; ; left ventricle; ; ascending aorta;
	Top expressed in
	right lung lobe; ; left lung; ; left lung lobe; ; interventricular septum; ; digastric muscle; ; cardiac muscles; ; myocardium of ventricle; ; right ventricle; ; extraocular muscle; ; thoracic diaphragm;
	More reference expression data
	More reference expression data
Orthologs
	90952
	69524
	ENSG00000149564
	ENSMUSG00000001946
	Q96AP7
	Q925F2
	NM_138961
	NM_027102
	NP_620411
	NP_081378
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated July 04, 2023

Endothelial cell-selective adhesion molecule is a protein that in humans is encoded by the ESAM gene.^[5]^[6]^[7]

Related Research Articles

Adhesion G-protein coupled receptor A3 (ADGRA3), also known as GPR125, is an adhesion GPCR that in humans is encoded by the Adgra3 gene.

Junctional adhesion molecule C is a protein that in humans is encoded by the JAM3 gene.

Chloride intracellular channel 4, also known as CLIC4,p644H1,HuH1, is a eukaryotic gene.

Neuronal cell adhesion molecule is a protein that in humans is encoded by the NRCAM gene.

Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene. JAM2 has also been designated as CD322.

DnaJ homolog subfamily B member 11 is a protein that in humans is encoded by the DNAJB11 gene.

DnaJ homolog subfamily B member 9 is a protein that in humans is encoded by the DNAJB9 gene.

Protocadherin beta-10 is a protein that in humans is encoded by the PCDHB10 gene.

Tetraspanin-4 is a protein that in humans is encoded by the TSPAN4 gene.

Glutathione peroxidase 7 is an enzyme that in humans is encoded by the GPX7 gene.

Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.

Claudin-10 is a protein that in humans is encoded by the CLDN10 gene. It belongs to the group of claudins.

Protocadherin beta-13 is a protein that in humans is encoded by the PCDHB13 gene.

Cell adhesion molecule 3 is a protein that in humans is encoded by the CADM3 gene.

Sodium channel subunit beta-2 is a protein that in humans is encoded by the SCN2B gene.

Endosialin is a protein that in humans is encoded by the CD248 gene.

C-type lectin domain family 1 member A is a protein that in humans is encoded by the CLEC1A gene.

Protocadherin-12 is a protein that in humans is encoded by the PCDH12 gene.

Leucine-rich repeat transmembrane protein FLRT3 is a protein that in humans is encoded by the FLRT3 gene.

A disintegrin and metalloproteinase with thrombospondin motifs 12 is an enzyme that in humans is encoded by the ADAMTS12 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000149564 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001946 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Hirata Ki, Ishida T, Penta K, Rezaee M, Yang E, Wohlgemuth J, Quertermous T (May 2001). "Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells". J Biol Chem. 276 (19): 16223–16231. doi: 10.1074/jbc.M100630200 . PMID 11279107.
↑ Sim DL, Yeo WM, Chow VT (Mar 2002). "The novel human HUEL (C4orf1) protein shares homology with the DNA-binding domain of the XPA DNA repair protein and displays nuclear translocation in a cell cycle-dependent manner". Int J Biochem Cell Biol. 34 (5): 487–504. doi:10.1016/S1357-2725(01)00156-X. PMID 11906820.
↑ "Entrez Gene: ESAM endothelial cell adhesion molecule".

Nasdala I, Wolburg-Buchholz K, Wolburg H, et al. (2002). "A transmembrane tight junction protein selectively expressed on endothelial cells and platelets". J. Biol. Chem. 277 (18): 16294–16303. doi: 10.1074/jbc.M111999200 . PMID 11847224.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID 14702039.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–2824. doi:10.1110/ps.04682504. PMC 2286551 . PMID 15340161.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–126. doi: 10.1093/dnares/12.2.117 . PMID 16303743.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000149564 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001946 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11279107-5] Hirata Ki, Ishida T, Penta K, Rezaee M, Yang E, Wohlgemuth J, Quertermous T (May 2001). "Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells". J Biol Chem. 276 (19): 16223–16231. doi: 10.1074/jbc.M100630200 . PMID 11279107.

[pmid11906820-6] Sim DL, Yeo WM, Chow VT (Mar 2002). "The novel human HUEL (C4orf1) protein shares homology with the DNA-binding domain of the XPA DNA repair protein and displays nuclear translocation in a cell cycle-dependent manner". Int J Biochem Cell Biol. 34 (5): 487–504. doi:10.1016/S1357-2725(01)00156-X. PMID 11906820.

[entrez-7] "Entrez Gene: ESAM endothelial cell adhesion molecule".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

ESAM (gene)

Related Research Articles

References

Further reading